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WHO Expert Committee on Biological Standardization PDF

354 Pages·2007·3.438 MB·English
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by World Health Organization| 2007| 354 pages| 3.438| English

About WHO Expert Committee on Biological Standardization

This report presents the recommendations of a WHO Expert Committee commissioned to coordinate activities leading to the adoption of international recommendations to assure the quality, safety and efficacy of vaccines, blood products and other biological medicines, and the establishment of international biological reference standards for these products and related diagnostic devices. The report, of particular relevance to manufacturers and national regulatory authorities, starts with a discussion of general issues brought to the Committee's attention.The second part of the report contains written specifications that establish international regulatory expectations for the following products; DNA vaccines, pertussis (whole cell) vaccine, plasma (human) for fractionation, rabies vaccine, and rotavirus vaccine. The report also provides a risk assessment and defines conditions for the safe production of pandemic strain influenza vaccines. The third part of the report provides information on the status and development of international reference materials for various antibodies, antigens, blood products and related substances, and in vitro diagnostic devices.

Detailed Information

Author:World Health Organization
Publication Year:2007
Pages:354
Language:English
File Size:3.438
Format:PDF
Price:FREE
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