Western Biomedicine and Eastern Therapeutics - An Integrative Strategy for Personalized and Preventive Healthcare

379 Pages·2013·32.761 MB·English

by  Sun-Chong Wang

Western Biomedicine
and
Eastern Therapeutics
An Integrative Strategy for
Personalized and Preventive Healthcare
b1522 Western Biomedicine and Eastern Therapeutics
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Western Biomedicine
and
Eastern Therapeutics
An Integrative Strategy for
Personalized and Preventive Healthcare
Sun-Chong Wang
National Central University, Taiwan
World Scientific
NEW JERSEY • LONDON • SINGAPORE • BEIJING • SHANGHAI • HONG KONG • TAIPEI • CHENNAI
Published by
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
USA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601
UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE
Library of Congress Cataloging-in-Publication Data
Wang, Sun-Chong, 1963–
Western biomedicine and Eastern therapeutics : an integrative strategy for
personalized and preventive healthcare / by Sun-Chong Wang.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-9814412872 (hardcover : alk. paper)
I. Title.
[DNLM: 1. Integrative Medicine. 2. Medicine, Ayurvedic. 3. Medicine, Chinese Traditional.
WB 113]
616--dc23
2012046513
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library.
Copyright © 2013 by World Scientific Publishing Co. Pte. Ltd.
All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means,
electronic or mechanical, including photocopying, recording or any information storage and retrieval
system now known or to be invented, without written permission from the Publisher.
For photocopying of material in this volume, please pay a copying fee through the Copyright
Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to
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Typeset by Stallion Press
Email: [email protected]
Printed in Singapore
JQuek - Western Biomedicine.pmd 1 3/8/2013, 5:17 PM
b1522 Western Biomedicine and Eastern Therapeutics
To my mother, Gao-Yue Wang,
for her love and patience
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b1522 Western Biomedicine and Eastern Therapeutics
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b1522 Western Biomedicine and Eastern Therapeutics
Contents
Preface xvii
Part I: Basics 1
Chapter 1 Evidence-Based Practice 3
1.1 The FDA Drug Approval Process 4
1.2 Randomized Controlled Trial 5
1.3 Level of Evidence 7
1.4 Cochrane Review 9
1.5 Drug Development 12
1.6 Translational Medicine 13
Chapter 2 Modern Western Biomedicine 17
2.1 ATP Hydrolysis 17
2.2 Oxidative Phosphorylation, the Electron
Transport Chain, the Krebs Cycle 18
2.3 Glycolysis, Aerobic Respiration,
the Warburg Effect 20
2.4 Reactive Oxygen Species, Oxidative
Stress, Redox Signaling 21
2.5 Cell Metabolism 22
2.6 The Central Dogma of Molecular
Biology, the Genome 24
vii
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viii Western Biomedicine and Eastern Therapeutics
2.7 Eukaryotic Cell Division Cycle 25
2.8 Meiosis, Mendelian Inheritance,
Genetic Disorder 27
2.9 Chromatin Modification, Complex
Disorder 30
2.10 Immunity, Hematopoiesis 33
Chapter 3 Traditional Oriental Ethnomedicine 37
3.1 Ayurveda 38
3.2 Asana, Pranayama, Dhyana 41
3.3 Traditional Chinese Medicine 44
3.4 Acupuncture 49
Chapter 4 Integrative Medicine 51
4.1 Bioenergetics, Tridosha, Chronic Disorder 52
4.2 Complex Adaptive System, Yogic
Cognitive-Behavioral Practice,
Psychological Stress Management 54
4.3 Placebo Effect, Acupuncture Analgesia,
Chronic Pain 57
4.4 P eriodontitis: An Example of Holistic
Therapy 60
4.5 Practical Clinical Trial for the Effectiveness
of Integrative Therapy 63
Part II Herbal Medicine 67
Chapter 5 Safety and Regulation of Herbal Products 69
5.1 Plant Secondary Metabolites 70
5.2 P harmacodynamic and Pharmacokinetic
Herb–Drug Interactions 71
5.3 R egulation of TCM and Other Natural
Herbal Products in China 73
5.4 Kampo Medicine in Japan 74
5.5 Regulation of TCM Medicine in Taiwan 74
5.6 Regulation of Natural Health Products
in Canada 75
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b1522 Western Biomedicine and Eastern Therapeutics
Contents ix
5.7 Botanical Products as Dietary
Supplements in the United States 75
5.8 Regulation of Traditional Herbal
Medicinal Products in the European
Union 76
Chapter 6 Cancer 79
6.1 S ix Core and Two Emerging Hallmarks
of Cancer 80
6.2 M echanisms of Hallmark Acquisition:
Genomic and Epigenomic Instability,
Inflammation; Microenvironment 84
6.3 F rontiers of Conventional Treatment:
Drug Cocktail Cotargeting Multiple
Hallmarks; Personalized Targeted
Therapy 86
6.4 TCM Carbuncle-Treating, TCM
Mediating Formulas; TCM Cold
Herbs Against Neoplasms 88
6.5 Uterine Leiomyoma: Gui Zhi Fu
Ling Wan and Yi Mu Cao 93
6.6 Benign Nonfibroid Neoplasm
of the Uterus: Gui Zhi Fu Ling Wan
and E Shu 95
6.7 Benign Neoplasm of the Ovary:
Gui Zhi Fu Ling Wan and Yi Mu Cao 97
6.8 Benign Neoplasm of the Thyroid Gland:
San Zhong Kui Jian Tang and Xia Ku Cao 99
6.9 Benign Neoplasm of the Breast:
Jia Wei Xiao Yao San and Pu Gong Ying 101
6.10 Lipoma: San Zhong Kui Jian Tang
and Bai Jie Zi 103
6.11 Benign Neoplasm of Male Genital Organs:
Ji Sheng Shen Qi Wan and Che Qian Zi 105
6.12 Benign Neoplasm of the Lower GI Tract
Digestive System: Ban Xia Xie Xin Tang
and Yan Hu Suo 107
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