Table Of ContentAdvances in Experimental Medicine and Biology 873
Neuroscience and Respiration
Mieczyslaw Pokorski Editor
Ventilatory
Disorders
Advances in Experimental Medicine
and Biology
Neuroscience and Respiration
Volume 873
Editorial Board
Irun R. Cohen, The Weizmann Institute of Science, Rehovot, Israel
N.S.AbelLajtha,KlineInstituteforPsychiatricResearch,Orangeburg,NY,USA
John D. Lambris, University of Pennsylvania, Philadelphia, PA, USA
Rodolfo Paoletti, University of Milan, Milan, Italy
Subseries Editor
Mieczyslaw Pokorski
Moreinformationabout thisseries athttp://www.springer.com/series/13457
Mieczyslaw Pokorski
Editor
Ventilatory Disorders
Editor
MieczyslawPokorski
PublicHigherMedicalProfessionalSchoolinOpole
InstituteofNursing
Opole,Poland
ISSN0065-2598 ISSN2214-8019 (electronic)
AdvancesinExperimentalMedicineandBiology
ISBN978-3-319-20193-1 ISBN978-3-319-20194-8 (eBook)
DOI10.1007/978-3-319-20194-8
LibraryofCongressControlNumber:2015958774
SpringerChamHeidelbergNewYorkDordrechtLondon
#SpringerInternationalPublishingSwitzerland2015
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Preface
The book series Neuroscience and Respiration presents contributions by
expert researchers and clinicians in the field of pulmonary disorders. The
chapters provide timely overviews of contentious issues or recent advances
in the diagnosis, classification, and treatment of the entire range of pulmo-
narydisorders,bothacuteandchronic.Thetextsarethoughtasamergerof
basic and clinical research dealing with respiratory medicine, neural and
chemical regulation of respiration, and the interactive relationship between
respiration and other neurobiological systems such as cardiovascular func-
tionorthemind-to-bodyconnection.Theauthorsfocusontheleading-edge
therapeutic concepts, methodologies, and innovative treatments. Pharmaco-
therapy is always in the focus of respiratory research. The action and
pharmacology of existing drugs and the development and evaluation of
new agents are the heady area of research. Practical, data-driven options to
manage patients will be considered. New research is presented regarding
older drugs, performed from a modern perspective or from a different
pharmacotherapeutic angle. The introduction of new drugs and treatment
approachesinbothadultsandchildrenalsoisdiscussed.
Lung ventilation is ultimately driven by the brain. However, neuropsy-
chologicalaspectsofrespiratorydisordersarestillmostlyamatterofconjec-
ture. After decades of misunderstanding and neglect, emotions have been
rediscovered as a powerful modifier or even the probable cause of various
somatic disorders. Today, the link between stress and respiratory health is
undeniable. Scientists accept a powerful psychological connection that can
directlyaffectourqualityoflifeandhealthspan.Psychologicalapproaches,
bydecreasingstress,canplayamajorroleinthedevelopmentandtherapyof
respiratorydiseases.
Neuromolecular aspects relating to gene polymorphism and epigenesis,
involvingbothheritablechangesinthenucleotidesequence,andfunctionally
relevantchangestothegenomethatdonotinvolveachangeinthenucleotide
sequence, leading to respiratory disorders will also be tackled. Clinical
advancesstemmingfrommolecularandbiochemicalresearcharebutpossi-
ble if the research findings are translated into diagnostic tools, therapeutic
procedures,andeducation,effectivelyreachingphysiciansandpatients.All
that cannot be achieved without a multidisciplinary, collaborative, bench-
to-bedsideapproachinvolvingbothresearchersandclinicians.
v
vi Preface
Thesocietalandeconomicburdenofrespiratoryailmentshasbeenonthe
rise worldwide leading to disabilities and shortening of life span. COPD
alone causes more than three million deaths globally each year. Concerted
efforts are required to improve this situation, and part of those efforts are
gaining insights into the underlying mechanisms of disease and staying
abreast with the latest developments in diagnosis and treatment regimens.
Itishopedthatthebookspublishedinthisserieswillassumealeadingrolein
the field of respiratory medicine and research and will become a source of
referenceandinspirationforfutureresearchideas.
I would like to express my deep gratitude to Mr. Martijn Roelandse and
Ms. Tanja Koppejan from Springer’s Life Sciences Department for their
genuineinterestinmakingthisscientificendeavorcomethroughandinthe
expertmanagementoftheproductionofthisnovelbookseries.
Opole,Poland MieczyslawPokorski
Volume 16: Ventilatory Disorders
Respiratory function is a major determinant of the overall quality of health
and well-being of an individual. This book runs the gamut of chapters
devoted to chronic cough-related conditions in children and adults, health
care quality and safety, environmental pollution health effects, efficiency
of therapeutic approaches and a mutual dependence of respiratory and
non-respiratory illnesses. An integrated approach to the investigation and
treatment of sleep disordered breathing as well as the use of new and more
efficientdiagnosticstrategiesforpleuraltuberculosisarepresented.Chapters
focus on translating science into practice, with an eye on presymptomatic
identification of serious ailments for which there could be more effective
therapy, leading to improved general health outcomes. This book includes
chapters about disorders which will be of interest to clinicians, family
practitionersandmedicalresearchers.
vii
Contents
GastroesophagealRefluxDiseaseinChildrenwith
CysticFibrosis. .. . . . .. . . .. . . .. . . .. . . .. . . .. . . . .. . . . 1
MarcinA.Dziekiewicz,AleksandraBanaszkiewicz,
AgnieszkaUrzykowska,AleksandraLisowska,MartaRachel,
DorotaSands,JaroslawWalkowiak,AndrzejRadzikowski,
andPiotrAlbrecht
Sleep-RelatedBreathingDisordersandBruxism. . . . . . . . . 9
J.Kostrzewa-Janicka,P.Jurkowski,K.Zycinska,
D.Przybyłowska,andE.Mierzwin´ska-Nastalska
AbsenceofTypicalSymptomsandComorbidities
inPatientswithCentralSleepApnea. . . . . . . . . . . . . . . . . . 15
JosefYayanandKurtRasche
CausesofChronicCoughinNon-smokingPatients. . . . . . . 25
M.Da˛browska,E.M.Grabczak,M.Arcimowicz,
A.Domeracka-Kołodziej,J.Domagała-Kulawik,R.Krenke,
M.Maskey-Warze˛chowska,B.Tarchalska,andR.Chazan
DiseasesoftheUpperRespiratoryTractinPreschool
andSchoolAgeChildreninAmbulatoryEarNose
ThroatPractice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
E.Dzie˛ciołowska-Baran,A.Gawlikowska-Sroka,
andM.Mularczyk
AssessmentofAirPollutionEffectsontheRespiratory
SystemBasedonPulmonaryFunctionTestsPerformed
DuringSpirometryDays. . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
PiotrDa˛browiecki,DominikaMucha,AnnaGayer,
ŁukaszAdamkiewicz,andArturJ.Badyda
DevelopmentandEvaluationoftheNewPredictiveModels
inTuberculousPleuritis. . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
J.Klimiuk,A.Safianowska,R.Chazan,P.Korczyn´ski,
andR.Krenke
ix
