Ultrastructure of the Male Urogenital Glands: Prostate, Seminal Vesicles, Urethral, and Bulbourethral Glands

207 Pages·1994·16.39 MB·English

by  Fred Sinowatz

Ultrastructure of Male Urogenital Glands
ELECTRON MICROSCOPY IN BIOLOGY
AND MEDICINE
Current Topics in Ultrastructural Research
SERIES EDITOR: P.M. MOTTA
Already published in this series
Vol. 1 Motta, P.M. (ed.): Ultrastructure of Endocrine Cells and Tissues. ISBN: 0-89838-568-7.
Vol. 2 Van Blerkom, J. and Motta, P.M. (eds.): Ultrastructure of Reproduction: Gametogenesis,
Fertilization, and Embryogenesis. ISBN: 0-89838-572-5.
Vol. 3 Ruggeri, A. and Motta, P.M. (eds.): Ultrastructure of the Connective Tissue Matrix. ISBN:
0-89838-600-4.
Vol. 4 Motta, P.M. and Fujita, H. (eds.): Ultrastructure of the Digestive Tract. ISBN: 0-89838-893-7.
Vol. 5 Van Blerkom, J. and Motta, P.M. (eds.): Ultrastructure of Human Gametogenesis and Early
Embryogenesis. ISBN: 0-89838-383-8.
Vol. 6 Riva, A. and Motta, P.M. (eds.): Ultrastructure ofthe Expatraparietal Glands of the Digestive
Tract. ISBN: 0-7923-0303-2.
Vol. 7 Bonucci, E. and Motta, P.M. (eds.): Ultrastructure of Skeletal Tissue. ISBN: 0-7923-0373-3.
Vol. 8 Motta, P.M. (ed.): Ultrastructure of Smooth Muscle. ISBN: 0-7923-0480-2.
Vol. 9 Familiari, G., Makabe, S., and Motta, P.M. (eds.): Ultrastructure ofthe Ovary. ISBN:
0-7923-1003-9.
Vol. 10 Motta, P.M., Murakami, T., and Fujita, H. (eds.): Scanning Electron Microscopy of Vascular
Casts: Methods and Applications. ISBN: 0-7923-1297-X.
Series Editor
P.M. MOTTA, Department of Anatomy, Faculty of Medicine, University of Rome "La Sapienza", via
A. Borelli, 50, 00161 Rome, Italy
Advisory Scientific Committee
D.J. ALLEN (Dahlonega, Georgia, USA)/ A. AMSTERDAM (Rehovot, Israel)/P.M. ANDREWS
(Washington, DC, USA)/L. BJERSING (Umea, Sweden)/I. BUCKLEY (Canberra, Australia)/F.
CARAMIA (Rome, Italy)/ A. COIMBRA (Porto, Portugal)1I. DICULESCU (Bucharest, Romania)/
L.J.A. DIDIO (Toledo, Ohio, USA)/M. DVORAK (Brno, Czechoslovakia)/H.D. FAHIMI (Heidel
berg, FRG)/H.V. FERNANDEZ-MORAN (Chicago, Illinois, USA)/H. FUJITA (Osaka, Japan)/T.
FUJITA (Niigata, Japan)/E. KLIKA (Prague, Czechoslovakia)/W. KOHNEL (Lubeck, FRG)/L.C.U.
JUNQUEIRA (Sao Paulo, Brazil)/R.G. KESSEL (Iowa City, Iowa, USA)/F.N. LOW (New Orleans,
Louisiana, USA)/B.L. MUNGER (Hersey, Pennsylvania, USA)/T. MURAKAMI (Okayama, Japan)/
O. NILSSON (Uppsala, Sweden)/ A. OKSCHE (Giessen, FRG)/K.R. PORTER (Philadelphia, Pen
nsylvania, USA)/J.A.G. RHODIN (Tampa, Florida, USA)/K. SMETANA (Prague, Czechoslovakia)/
K. TANAKA (Yonago, Japan)/K. TANIKAWA (Kurume, Japan)/I. TORO (Budapest, Hungary)/J.
VAN BLERKOM (Boulder, Colorado, USA)
Ultrastructure of the Male Urogenital
Glands: Prostate, Seminal Vesicles,
Urethral, and Bulbourethral Glands
edited by
Alessandra Riva, M.D.
Department of Cytomorphology, University of Cagliari,
Cagliari, ltaly
and
Francesca Testa Riva, Ph.D.
Department of Cytomorphology, University of Cagliary
Cagliari, ltaly
and
Pietro Matta, M.D., Ph.D.
Department of Human Anatomy, Faculty of Medicine, University of Rome "La Sapienza"
Rome,ltaly
Springer-Science+Business Media, LLC
Library of Congress Cataloging-in-Publication Data
Ultrastructure of the male urogemtal glands prostate, semmal
vcslcles, urethral, and bulbourethral glands / edlted by
Alessandro Rlva, Francesca Testa Rlva, Pletro Molta
p cm - (Electron mlcroscopy m blOlogy and medlcme,
EMBMII)
Include~ blbhographlcal references and mdex
ISBN 978-1-4613-6125-1 ISBN 978-1-4615-2624-7 (eBook)
DOI 10.1007/978-1-4615-2624-7
1 Generatlve organs, Male-
Ultrastructure 2 Andrology
I Rlva, Alessandro II Testa Rlva,
Francesca III Motta, Pletro M IV Se nes
[DNLM 1 Gemtaha, Malc-ultrastructurc WJ 701
U4719941
QP257 U58 1994
611' 63-dc20
DNLM/DLC
for Llbrary of Congress 94-11636
CIP
Copyright © 1994 by Springer Science+Business Media New York
Originally published by Kluwer Academic Publishers, New York in 1994
Softcover repdnt ofthe ha,-dcove,-Ist edition 1994
AII nghts reserved No part of thls pubhcatIon may bc
rcproduccd. storcd m d rctneval system or transmltted m dny
fonTI or by dny mc.ms. mcchamcdl, photo-copymg, recordmg,
or othcrwl~c. wlthout thc pnor wntten permlsslon of thc
pubhshcr. Springer Science+Business Media, LLC.
Prtll!ed UII il( Id-}ree papa
Preface
Male urogenital glands (also termed male accessory sex glands) have received relatively little attention
from electron microscopists, with perhaps the exception of the prostate gland. Moreover, even though
comparative studies have clearly shown that these glands exhibit species dependent features, very few
studies, scattered among various publications, are available on the urogenital glands of man.
This volume, the 11th of the series Electron Microscopy in Biology and Medicine, presents an
unprecedented collection of information on the functional microanatomy and cytoarchitecture of these
organs in humans.
Through the integration of transmission and scanning electron microscopy with a variety of modern
techniques, it documents the most important aspects of the histophysiology of these glands from their
development to some pathological alterations. In order to cover some key mechanisms of their cell
biology, such as the action of sex hormones, the epithelio-mesenchymal interactions, and the dynamic of
the secretory process, reports on human organs have been supplemented by some studies on experi
mental animals.
On the basis of the outstanding level of the contributions and the quality of the illustrations, we believe
that this book, which has been compiled by some of the world authorities on the topic, will serve not only
as a reference work for students, scientists, and professionals interested in biomedical foundations of
andrology, but also as a stimulus for future research in this exciting and relatively neglected chapter of
human reproduction.
Finally, we wish to thank Mr. J.K. Smith and his staff, who once again have fully demonstrated their
professional skill in the production of the book.
A. Riva, P.M. Motta, and F. Testa-Riva
Prof LIberato J A DIDIO
This book is dedicated to our friend Prof. Dr. Liberato J .A. DiDio as a tnbute to the first Honorary
President of the International Federation of Associations of Anatomists (1989), Ementus Professor
and Emeritus Dean of the Medical College of Ohio
A. Riva, F. Testa-Riva, and P.M. Motta, editors
Contents
Preface by the editors ................................................................. v
Contributing authors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl
1. Normal and abnormal development of human male accessory sex glands by F. Sinowatz,
P. Kellokumpu-Lehtinen, & W. Amselgruber . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
2. Role of mesenchymal-epithelial interactions in normal and abnormal development of
male urogenital glands by G. Cunha ................................................ 15
3. Epithelium of the distal portion of the human spermatic pathway: Seminal vesicle,
ampulla ductus deferentis, and ejaculatory duct by A. Riva & G. Aumiiller . . . . . . . . . . . . . . . 35
4. Secretion and endocytosis in the seminal vesicles by L. Mata. . . . . . . . . . . . . . . . . . . . . . . . . . . . 51
5. Functional morphology of prostate gland by G. Aumiiller, J. Seitz, & A. Riva. . . . . . . . . . . . . 61
6. Female prostatic glands: A comparative study by L.J.A. DiDio & S. Correr .............. 113
7. Histochemistry and electron microscopy for diagnosis of prostatic cancer by C. Capella,
B. Frigerio, G. Finzi, M. Salvadore, & A. Bono. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
8. A review of the ultrastructure of human prostatic and urethral endocrine-paracrine cells
and neuroendocrine differentiation in prostatic carcinoma by K.L. De Mesy Jensen &
P.A. Di Sant'Agnese . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139
9. Human bulbourethral and urethral glands by F. Testa-Riva, A. Riva, T. Congiu,
A. De Lisa, & P.M. Motta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163
10. ABH and Lewis antigens in human male accessory sex glands by M. Cossu, M.S. Lantini,
& R. Migliari ................................................................... 177
11. Autonomic innervation ofthe human male accessory sex glands by A. Vaalasti . . . . . . . . . . . . 187
Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197
Contributing Authors
Amselgruber, Werner, 2nd Chair of Veterinary Anatomy, Universitat Miinchen, Veterinarstrasse 13,
D 8000 Miinchen 22, Germany
Aumiiller, Gerhard, Department of Anatomy and Cell Biology, Klinikum der Philipps Universitat,
Robert Koch Strasse 6, D 35033 Marburg, Germany
Bono, Aldo, Division of Urology, Multizonal Hospital of Varese, Viale L. Borri 57, I 21100 Varese, Italy
Capella, Carlo, Department of Human Pathology, 2nd Faculty of Medicine, University of Pavia at
Varese, Viale L. Borri 57, 121100 Varese, Italy
Congiu, Terenzio, Department of Cytomorphology, University of Cagliari, Via Porcell 2, I 09124,
Cagliari, Italy
Correr, Silvia, Department of Anatomy, Faculty of Medicine, University "La Sapienza", Via A. Borelli
50, I 00161 Rome, Italy
Cossu, Margherita, Department of Cytomorphology, University of Cagliari, Via Porcell 2, I 09124,
Cagliari, Italy
Cunha, Gerald R., Anatomy Department, University of California, San Francisco, California, 94143
USA
De Lisa, Antonello, Clinic of Urology, University of Cagliari, Ospedale SS Trinita, 109100 Cagliari, Italy
De Mesy Jensen, Karen L., University of Rochester School of Medicine and Dentistry, Department of
Pathology and Laboratory Medicine, 575 Elmwood Ave., Rochester, New York 14642, USA
DiDio, Liberato J.A., Department of Morphology, Escola Paulista de Medicina, Rua Botucatu 740, Siiu
Paulo, SP 04023-900 Brasil
Di Sant'Agnese, P. Antony, University of Rochester School of Medicine and Dentistry, Department of
Pathology and Laboratory Medicine, 575 Elmwood Ave., Rochester, New York 14642, USA
Finzi, Giovanna, Department of Pathology, Multizonal Hospital of Varese, Viale L. Borri 57, 121100
Varese, Italy
xii
Frigerio, Bruno, Department of Pathology, General Hospital of Saronno, Piazzale Borella 3, I 21047
Saronno (Varese), Italy
Kellokumpu-Lehtinen, Pirkko, Department of Clinical Medicine/Oncology, University of Tampere, SF
33101 Tampere, Finland
Lantini, Maria Serenella, Department of Cytomorphology, University of Cagliari, Via Porce1l2, 109124,
Cagliari, Italy
Mata, Lucinda, Cell Biology Department, Gulbenkian Institute of Science, Apartado 14, 2781 Oeiras
of Codex, Portugal
Motta, Pietro M., Department of Anatomy, Faculty of Medicine, University "La Sapienza", Via A.
Borelli 50, I 00161 Rome, Italy
Migliari, Roberto, Clinic of Urology, University of Cagliari, Ospedale SS Trinita, 109100 Cagliari, Italy
Riva, Alessandro, Department of Cytomorphology, University of Cagliari, Via Porcell 2, I 09124,
Cagliari, Italy
Salvadore, Maurizio, Department of Pathology, Multizonal Hospital of Varese, Viale L. Borri 57, 121100
Varese, Italy
Seitz, Jiirgen, Department of Anatomy and Cell Biology, Klinikum der Philipps Universitat, Robert
Koch Strasse 6, D 35033 Marburg, Germany
Sinowatz, Fred, 2nd Chair of Veterinary Anatomy, Universitat Munchen, Veterinarstrasse 13, D 8000
Munchen 22, Germany
Testa-Riva, Francesca, Department of Cytomorphology, University of Cagliari, Via Porcell 2, 109124,
Cagliari, Italy
Vaalasti, Annikki, Department of Biomedical Sciences, University of Tampere, Box 2000, SF 33521
Tampere, Finland
Ultrastructure of Male Urogenital Glands