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Tumor Necrosis Factor PDF

260 Pages·2009·4.153 MB·English
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by Toma P. Rossard| 2009| 260 pages| 4.153| English

About Tumor Necrosis Factor

Tumor Necrosis Factor (TNF) is a member of a super family of proteins, each with 157 amino acids, which induce necrosis (death) of tumor cells and possess a wide range of proinflamTumor actions. Tumour necromulti functional multifunctional cytokine with effects on lipid metabolism, coagulation, insulin resistance, and the function of endothelial cells lining blood vessels. Blocking the action of TNF has been shown to be beneficial in reducing the inflammation in inflammatory diseases such as Crohn's disease and rheumatoid arthritis. Inappropriate production of TNF or sustained acsignalingf TNF signalling has been implicated in the pathogenesis of a wide spectrum of human diseases that include cancer, osteoporosis, sepsis, diabetes, and auto-immune diseases such as multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease. Extensive research within the last two decades has shown that TNF can be a potential therapeutic agent in various diseases. This new important book gathers the latest research from around the globe in this field.

Detailed Information

Author:Toma P. Rossard
Publication Year:2009
ISBN:9781607417088
Pages:260
Language:English
File Size:4.153
Format:PDF
Price:FREE
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