Table Of ContentYing Xia E ditor
Translational
Acupuncture
Research
Translational Acupuncture Research
Ying Xia
Editor
Translational Acupuncture
Research
123
Editor
YingXia
ShanghaiKey Laboratory of Acupuncture
Mechanism andAcupoint Function
FudanUniversity
Shanghai, China
Laboratory of Molecular Neurology
ShanghaiResearch Center for Acupuncture
andMeridians
Shanghai, China
ISBN978-3-030-16087-6 ISBN978-3-030-16089-0 (eBook)
https://doi.org/10.1007/978-3-030-16089-0
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Preface
Acupuncturehasbeenbroadlyusedinmanyclinicalsettingsworldwide.Although
the precise mechanism underlying the therapy is not well understood yet, it is
generallyacceptedthatacupuncture,byeithermanualorelectricalstimulation,can
triggernervesignalsintheacupointsthatgettransmittedfromtheperipheraltothe
central nervous system and elicit a therapeutic effect through neural and humoral
regulation.Inrecentyears,ourserialbooks(XiaY.etal.:AcupunctureTherapyfor
Neurological Diseases—A Neurobiological View. Springer-Tsinghua Press, 2010;
Xia Y. et al.: Current Research in Acupuncture. Springer, 2012; Xia Y.: Neural
Functions of the Delta-opioid Receptor. Springer 2015) have presented compre-
hensive information on acupuncture mechanisms and provided future perspectives
in acupuncture research.
Thisnewbookfeaturesatranslationalviewofacupunctureresearch.Writtenby
many scientists and clinicians from China, USA, Canada, and other countries, this
monograph discusses translational research on acupuncture.Besides general topics
onacupuncturepractice(e.g.,differentstylesandtechniquesofacupuncture),topics
include some refractory diseases such as chronic fatigue syndrome, Parkinson’s
disease, cardiovascular dysfunction, chronic pain, post-concussion syndrome,
post-traumatic stress disorder, and cancer-related symptoms. The factors influenc-
ing acupuncture research are comprehensively addressed in the final chapter. This
unique book provides a translational perspective on modern acupuncture for not
onlyacupuncturists,butalsoneuroscientists,neurologists,andotherclinicians.For
medicalstudentsandundergraduateandgraduatestudentsmajoringinbiology,this
book is an advanced course for learning the progress in alternative and comple-
mentary medicine.
I hope that this book will help promote acupuncture research in both basic and
clinical sides and further improve our understanding of acupuncture mechanisms
and increase acupuncture efficacy.
v
vi Preface
I am very grateful to all authors for their significant contributions and consid-
erable efforts that made this book happen. I would also like to thank Ms. Simina
Calin of Springer for her support and help for making this book to actuality from
my proposal.
Shanghai, China Ying Xia
Acknowledgements
This book would not have been possible without the support from
Fudan University;
Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function;
Shanghai Research Center for Acupuncture and Meridians;
Shanghai Hudong Hospital;
Science and Technology Commission of Shanghai Municipality (18401970100,
15441903800 & 14DZ2260500);
National Natural Science Foundation of China (81873361).
vii
Contents
Acupuncture: A Therapeutic Modality, But not a Placebo. . . . . . . . . . . 1
Martin Wang
Acupuncture Styles in Current Practice. . . . . . . . . . . . . . . . . . . . . . . . . 75
Martin Wang
Acupuncture Treatment for Chronic Fatigue Syndrome . . . . . . . . . . . . 165
Fei Yao, Yanli You, Xuan Yin, Dhea Khiati and Ying Xia
Acupuncture Cardiovascular Regulation: Translational,
Clinical Studies and Underlying Mechanisms. . . . . . . . . . . . . . . . . . . . . 217
Stephanie C. Tjen-A-Looi, Peng Li, John C. Longhurst and Shaista Malik
Electroacupuncture Inhibition of Hypertension is Slow Onset
and Long-Lasting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241
Peng Li, Stephanie C. Tjen-A-Looi and John C. Longhurst
Acupuncture Treatment for Pain: Clinical and Laboratory
Research. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249
Ting Wang, Zhiyan Sui, Terry C. Xia, Guoqiang Wen and Ying Xia
Effect of Acupuncture on Parkinson’s Disease . . . . . . . . . . . . . . . . . . . . 309
Tao Chen, Yanhui Liu, Yidong Deng, Shan Zhang, Si Teng, Benchi Cai
and Jiali Su
Aung Vital Energetic Alignment: The Answer to Post-concussion
Syndrome and Post-traumatic Stress Disorder. . . . . . . . . . . . . . . . . . . . 335
Steven K. H. Aung
Acupuncture in Oncology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373
E. D’Alessandro
Electrotherapy-An Old Technique for a New Use . . . . . . . . . . . . . . . . . 407
Shu-Ming Wang
ix
xx CCoonntteennttss
Factors Influencing Acupuncture Research . . . . . . . . . . . . . . . . . . . . . . 421
Martin Wang and Ying Xia
Index .... .... .... .... .... ..... .... .... .... .... .... ..... .... 485
About the Editor
Ying Xia is a Fudan Distinguished Professor at Fudan
University, the Executive Director of Shanghai Key
Laboratory of Acupuncture Mechanism and Acupoint
Function,andDirectorofMolecularNeurologyLaboratory
at Shanghai Research Center for Acupuncture and
Meridians, Shanghai, China. He obtained his medical
trainingatSoochowMedicalCollege,China.Afterbeinga
clinical physician for almost 4 years, he pursued his
graduatestudyandobtainedaMasterDegreeofMedicine
and a Doctoral Degree of Medical Science (Ph.D.) in
Neurobiology and Integrative Medicine at Shanghai
Medical University (now Shanghai Medical College of
Fudan University), China. He was then appointed as a
lecturer of Integrative Medicine and Neurobiology there.
Dr.XiajoinedYaleUniversitySchoolofMedicinein1988
for his postdoctoral training and initiated his laboratory at
Yale in 1994. During his 22-yearacademic career at Yale
University School of Medicine, he was appointed as a
faculty member in 1993 and promoted to Associate
Professor in 2002. From May 2010 to August 2016, he
worked at the University of Texas Medical School at
Houston(nowtheUniversityofTexasMcGovernMedical
School) and the University of Texas Graduate School of
Biomedical Sciences at Houston as a Full Professor,
Chairman of Research and Promotion Committee, and
Vice-chairman for Research in the Department of
Neurosurgery. He was recruited by Fudan University in
September 2016.
Dr. Xia’s early research focused on cardiovascular
regulation, interactive modulation of endogenous opi-
oidsandotherneurotransmitters,andthemechanismof
xi
