Transcriptional and Translational Regulation of Stem Cells

370 Pages·2013·8.83 MB·English

by  Gary R. Hime

Advances in Experimental Medicine and Biology 786
Gary Hime
Helen Abud Editors
Transcriptional
and Translational
Regulation of
Stem Cells
Transcriptional and Translational
Regulation of Stem Cells
Advances in Experimental Medicine and Biology
Volume 786
Editorial Board:
IRUN R. COHEN, The Weizmann Institute of Science
ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research
JOHN D. LAMBRIS, University of Pennsylvania
RODOLFO PAOLETTI, University of Milan
For further volumes:
http://www.springer.com/series/5584
Gary Hime (cid:129) Helen Abud
Editors
Transcriptional
and Translational
Regulation
of Stem Cells
Editors
Gary Hime Helen Abud
Anatomy and Neuroscience Anatomy and Developmental Biology
University of Melbourne Monash University
Parkville , VIC , Australia Clayton , VIC , Australia
ISSN 0065-2598
ISBN 978-94-007-6620-4 ISBN 978-94-007-6621-1 (eBook)
DOI 10.1007/978-94-007-6621-1
Springer Dordrecht Heidelberg New York London
Library of Congress Control Number: 2013939599
© Springer Science+Business Media Dordrecht 2013
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Contents
1 The Stem Cell State ...................................................................... 1
Gary R. Hime and Helen E. Abud
2 Induction of Pluripotency............................................................ 5
Corey Heffernan, Jun Liu, Huseyin Sumer,
Luis F. Malaver-Ortega, Rajneesh Verma,
Edmund Carvalho, and Paul J. Verma
Part I Model Stem Cell Systems
(A) Invertebrate
3 Germline Stem Cells and Their Regulation
in the Nematode Caenorhabditis elegans .................................... 29
Aaron Kershner, Sarah L. Crittenden, Kyle Friend,
Erika B. Sorensen, Douglas F. Porter, and Judith Kimble
4 Transcriptional and Post-transcriptional Regulation
of Drosophila Germline Stem Cells and Their
Differentiating Progeny ............................................................... 47
Helen White-Cooper and Simona Caporilli
5 Stem Cells in the Drosophila Digestive System .......................... 63
Xiankun Zeng, Chhavi Chauhan, and Steven X. Hou
6 Mechanisms of Asymmetric Progenitor Divisions
in the Drosophila Central Nervous System ................................ 79
Rita Sousa-Nunes and W. Gregory Somers
Part II Model Stem Cell Systems
(B) Vertebrate
7 Transcriptional/Translational Regulation
of Mammalian Spermatogenic Stem Cells ................................. 105
Cathryn A. Hogarth
vv
vi Contents
8 Transcriptional Regulation and Specification
of Neural Stem Cells .................................................................... 129
Kimberly J. Christie, Ben Emery, Mark Denham,
Helena Bujalka, Holly S. Cate, and Ann M. Turnley
9 Transcriptional Control of Epidermal Stem Cells .................... 157
Briana Lee and Xing Dai
10 Regulation of Intestinal Stem Cells by Wnt
and Notch Signalling .................................................................... 175
Katja Horvay and Helen E. Abud
11 Transcriptional regulation of haematopoietic stem cells ......... 187
Adam C. Wilkinson and Berthold Göttgens
12 Regulation of Mesenchymal Stem Cell Differentiation ............ 213
David Cook and Paul Genever
Part III Molecular Families Implicated in Stem Cell Regulation
13 The Musashi Family of RNA Binding Proteins:
Master Regulators of Multiple Stem Cell Populations ............. 233
Jessie M. Sutherland, Eileen A. McLaughlin,
Gary R. Hime, and Nicole A. Siddall
14 JAK-STAT Signaling in Stem Cells ............................................ 247
Rachel R. Stine and Erika L. Matunis
15 Myc in Stem Cell Behaviour: Insights from Drosophila ........... 269
Leonie M. Quinn, Julie Secombe, and Gary R. Hime
16 The Role of Nuclear Receptors in Embryonic Stem Cells ........ 287
Qin Wang and Austin J. Cooney
17 Epigenetic Regulation of Stem Cells:
The Role of Chromatin in Cell Differentiation ......................... 307
Anton Wutz
18 Regulation of Stem Cell Populations by microRNAs ................ 329
Julie Mathieu and Hannele Ruohola-Baker
19 Myb and the Regulation of Stem Cells
in the Intestine and Brain: A Tale of Two Niches ...................... 353
Jordane Malaterre, Lloyd Pereira, and Robert G. Ramsay
Index ...................................................................................................... 369
Contributors
Helen E. Abud Department of Anatomy and Developmental Biology ,
Monash University , Clayton , VIC , Australia
Helena Bujalka Department of Anatomy and Neuroscience, Centre for
Neuroscience Research , The University of Melbourne , Parkville, Melbourne ,
VIC , Australia
Simona Caporilli Cardiff School of Biosciences , Cardiff University ,
Cardiff , UK
Edmund Carvalho Reprogramming and Stem Cell Laboratory, Centre for
Reproduction and Development , Monash Institute of Medical Research,
Monash University , Clayton , VIC , Australia
Holly S. Cate Department of Anatomy and Neuroscience, Centre for
Neuroscience Research , The University of Melbourne , Parkville, Melbourne ,
VIC , Australia
Chhavi Chauhan The Mouse Cancer Genetics Program , National Cancer
Institute at Frederick, National Institutes of Health , Frederick , MD , USA
Kimberly J. Christie Department of Anatomy and Neuroscience, Centre
for Neuroscience Research , The University of Melbourne , Parkville,
Melbourne , VIC , Australia
David Cook Department of Biology , University of York , York , UK
Austin J. Cooney Department of Molecular and Cellular Biology , Baylor
College of Medicine , Houston , TX , USA
Sarah L. Crittenden Howard Hughes Medical Institute, Department of
Biochemistry, University of Wisconsin , Madison , WI , USA
Xing Dai Department of Biological Chemistry, School of Medicine ,
University of California , Irvine , CA , USA
Mark Denham Department of Anatomy and Neuroscience, Centre for
Neuroscience Research , The University of Melbourne , Parkville, Melbourne ,
VIC , Australia
vii
viii Contributors
Ben Emery Department of Anatomy and Neuroscience, Centre for
Neuroscience Research , The University of Melbourne , Parkville, Melbourne ,
VIC , Australia
Kyle Friend Department of Biochemistry , University of Wisconsin-Madison ,
Madison , WI , USA
Paul Genever Department of Biology , University of York , York , UK
Berthold Göttgens Department of Haematology, Cambridge Institute for
Medical Research , University of Cambridge , Cambridge , UK
Corey Heffernan Reprogramming and Stem Cell Laboratory, Centre for
Reproduction and Development , Monash Institute of Medical Research,
Monash University , Clayton , VIC , Australia
Gary R. Hime Department of Anatomy and Neuroscience , University of
Melbourne , Parkville, Melbourne , VIC , Australia
Cathryn A. Hogarth School of Molecular Biosciences and the Centre for
Reproductive Biology , Washington State University , Pullman , WA , USA
Katja Horvay Department of Anatomy and Developmental Biology ,
Monash University , Clayton , VIC , Australia
Steven X. Hou The Mouse Cancer Genetics Program , National Cancer
Institute at Frederick, National Institutes of Health , Frederick , MD , USA
Aaron Kershner Department of Biochemistry , University of Wisconsin-
Madison , Madison , WI , USA
Judith Kimble Howard Hughes Medical Institute, Department of
Biochemistry , University of Wisconsin-Madison , Madison , WI , USA
Program in Cellular and Molecular Biology , U niversity of Wisconsin-Madison ,
Madison , WI , USA
Briana Lee Department of Biological Chemistry, School of Medicine ,
University of California , Irvine , CA , USA
Jun Liu Reprogramming and Stem Cell Laboratory, Centre for Reproduction
and Development , Monash Institute of Medical Research, Monash University ,
Clayton , VIC , Australia
Jordane Malaterre Cancer Cell Biology Program, Peter MacCallum Cancer
Centre , East Melbourne , VIC , Australia
Pathology Department , The University of Melbourne , Parkville, Melbourne ,
VIC , Australia
Luis F. Malaver-Ortega Reprogramming and Stem Cell Laboratory, Centre
for Reproduction and Development , Monash Institute of Medical Research,
Monash University , Clayton , VIC , Australia
Julie Mathieu Department of Biochemistry, Institute for Stem Cell and
Regenerative Medicine , University of Washington , Seattle , WA , USA
Contributors ix
Erika L. Matunis Department of Cell Biology , Johns Hopkins University
School of Medicine , Baltimore , MD , USA
Eileen A. McLaughlin Priority Research Centre in Reproductive Science,
School of Environmental and Life Sciences , University of Newcastle ,
Callaghan , NSW , Australia
Lloyd Pereira Cancer Cell Biology Program, Peter MacCallum Cancer
Centre , East Melbourne , VIC , Australia
Pathology Department , The University of Melbourne , Parkville, Melbourne ,
VIC , Australia
Douglas F. Porter Program in Cellular and Molecular Biology , University
of Wisconsin-Madison , Madison , WI , USA
Leonie M. Quinn Department of Anatomy and Neuroscience , University of
Melbourne , Parkville, Melbourne , VIC , Australia
Robert G. Ramsay Cancer Cell Biology Program, Peter MacCallum Cancer
Centre , East Melbourne , VIC , Australia
Pathology Department , The University of Melbourne , Parkville, Melbourne ,
VIC , Australia
Hannele Ruohola-Baker Department of Biochemistry, Institute for Stem Cell
and Regenerative Medicine , University of Washington , Seattle , WA , USA
Julie Secombe Department of Genetics, Albert Einstein College of
Medicine , Bronx, New York , NY , USA
Nicole A. Siddall Department of Anatomy and Neuroscience , University of
Melbourne , Parkville, Melbourne , VIC , Australia
W. Gregory Somers Department of Genetics , La Trobe Institute for
Molecular Science (LIMS), La Trobe University , Melbourne , VIC , Australia
Erika B. Sorensen Howard Hughes Medical Institute , D epartment of
Biochemistry, University of Wisconsin, Madison , WI , USA
Rita Sousa-Nunes Medical Research Council , National Institute for Medical
Research , Mill Hill, London , UK
Medical Research Council Centre for Developmental Neurobiology , King’s
College London , London , UK
Rachel R. Stine Department of Cell Biology , Johns Hopkins University
School of Medicine , Baltimore , MD , USA
Huseyin Sumer Reprogramming and Stem Cell Laboratory, Centre for
Reproduction and Development , Monash Institute of Medical Research,
Monash University , Clayton , VIC , Australia
Jessie M. Sutherland Priority Research Centre in Reproductive Science,
School of Environmental and Life Sciences , University of Newcastle ,
Callaghan , NSW , Australia