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TRAIL (TNF-Related Apoptosis-Inducing Ligand) PDF

492 Pages·2004·6.545 MB·English
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by Gerald Litwack (Eds.)| 2004| 492 pages| 6.545| English

About TRAIL (TNF-Related Apoptosis-Inducing Ligand)

The discovery of TRAIL (TNF Related Apoptosis Inducing Ligand), also referred to as Apo-2, is in an era of intense research because TRAIL induces many cancer cells to undergo programmed cell death (apoptosis), while having no effect on normal cells. This important protein deserves extensive review at a formative time in the devlopement of our knowledge concerning its mechanism of action and the ways in which it can be used as a cancer chemotherapeutic agent. Consequently, this voume reviews the current status of research on TRAIL. Selected Contents:* Crystal Structure of RANK Ligand involved in bone metabolism* Promoter of TRAIL-R2 Gene* Monoclonal Antibodies against TRAIL* Modulation of TRAIL signaling complex* TRAIL in the airways* FLIP Protein and TRAIL-Induced Apoptosis* TRAIL and Ceramide* TRAIL and Viral Infection* TRAIL and Malignant Glioma

Detailed Information

Author:Gerald Litwack (Eds.)
Publication Year:2004
ISBN:9780127098678
Pages:492
Language:English
File Size:6.545
Format:PDF
Price:FREE
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