The synthesis and characterization of novel platinum and palladium diimene compounds for use as anticancer drugs and CO2 reduction catalyst

370 Pages·2003·5.1 MB·English

by  Payne, Emma Kate

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The Synthesis and Characterization ofNovel Platinum and Palladium
Diimene Compounds ForUse as Anticancer Drugs and COiReduction
Catalyst
A SeniorHonorsResearch Thesis in the
DepartmentofChemistry
SubmittedtotheHonors Committee of
SweetBriarCollege
ByEmmaKatePayne
In PartialFulfillmentoftheRequirements
FortheHonorsDegreeofBachelorofScience
in Chemistry
May2003
ResearchAdvisorsandThesis Committee:
Dr. RobertM. Granger, SweetBriarCollege
Dr. Robin L. Davies, SweetBriarCollege
OutsideReader:
Dan Derringer, Hollins University,

Formyparents, mybrother.Papa, andall myfriends forunderstanding andsupportwhen
Ineededit.

Acknowledgements
Iamthankful to manypeoplethroughoutthis work. Thank youDr. Robert
Granger, my advisor, throughoutthe summer2001, thejunioryear2002, the summer
2002, andthe seniorhonors research. Youhave helpedme immensely. Yourguidance
hasenabledme tofindcourageandstrength within myselftobelieve in the talents thatI
possess. The knowledge andskills thatyoutaughtmein the laboratory will be invaluable
throughout myfuture in graduate school. Thankyou foryoursupportandbeliefin me.
Tothe Chemistryfacultyandstaff, thankyou also foryoursupportandthe knowledge
that youpassedon to me. Dr. John Beck, thank you forpushingmetoreach beyondthe
norm. Dr. Susan Piepho. thankyouformakingphysical chemistryinterestingandfor
supportingme in mypursuittostudyabroad. Mytime abroadwill neverbe forgotten.
Dr. Jill Granger, thank you forpushing me tounderstandall aspectsofbiochemistry and
forbelievingthatIcouldsucceed. Thank you alsoto the Honors Departmentforworking
with meduringthe past fouryears toensure that I was on task. Thank you to my friends
at SweetBriarCollege. You haveremainedtrue andhaveprovidedsupport and love
when Ineededitthe most. Thankyouespeciallyto myroommate,Christy Pitts, whohas
stoodbeside me through all the ups anddowns. Thank you also to my familyandPapa.
You have always toldme that Ican accomplish anythingandneverdoubtedthat Icould
even when Idid. You have helpedme become the woman thatI amtoday, andforthatI
am verygrateful. I love, admire, respect, andcherish you all.
Numerous grants have made thisprojectpossible includingtheJeffress Memorial
TrustResearch Grant andtheCommonwealth Health Research Board. Also the SBC
SummerHonors Research Fellowship, which supportedmeduringthe summerof2001.