The Fetal Heart - Vrije Universiteit Amsterdam

172 Pages·2011·2.38 MB·English

by  Bart Smit

The Fetal Heart
Lukas Bastiaan Uittenbogaard
The studies described in this thesis were performed at the Division of Prenatal
Medicine and Screening, Department of Obstetrics and Gynecology, VU University
medical Center, Amsterdam, the Netherlands.
Financial support by the Netherlands Heart Foundation for the publication of this
thesis is gratefully acknowledged.
Financial support was also kindly provided by Bayer Schering Pharma, BMA BV
(Mosos), Esaote-Pie Medical Benelux BV, Medical Dynamics, Medimast, Posthumus
Meyjesfonds, Stichting perinatologisch onderzoek en onderwijs.
ISBN: 9789086595389
Thesis VU University medical center, Amsterdam with summary in Dutch.
design: Lukas Uittenbogaard (cover) and Bart Smit
print: Optima Grafische Communicatie, Rotterdam
© L.B. Uittenbogaard, Amsterdam, the Netherlands, 2011.
No part of this thesis may be reproduced in any form or by any means, by print,
photocopy, microfilm or any other means without permission of the author.
VRIJE UNIVERSITEIT
The Fetal Heart
ACADEMISCH PROEFSCHRIFT
ter verkrijging van de graad van Doctor aan
de Vrije Universiteit Amsterdam,
op gezag van de rector magnificus
prof. dr. L.M. Bouter,
in het openbaar te verdedigen
ten overstaan van de promotiecommissie
van de faculteit der Geneeskunde
op vrijdag 1 april 2011 om 13.45 uur
in de aula van de universiteit,
Boelelaan 1105
door
Lukas Bastiaan Uittenbogaard
geboren te Hilversum
promotor: prof.dr. J.M.G. van Vugt
copromotor: dr. M.C. Haak
5
with special gratitude to the review committee
Professor H.A.M. Brölmann, MD, PhD, VU University medical center, Amsterdam
Professor T. van der Steen, MD, PhD, Erasmus MC, Rotterdam
Professor J. Hruda, MD, PhD, VU University medical center, Amsterdam
J. Simpson, MD, FRCP, Evelina Chilrden’s Hospital, St. Thomas’ Hospital, London
D. Oepkes, MD, PhD, Leiden University Medical Center, Leiden
Ph. Stoutenbeek, MD, PhD, University Medical Center Utrecht, Utrecht
6 the fetal heart
CONTENT
1 General introduction 9
2 A systematic analysis of the feasibility of four-dimensional ultrasound 17
imaging using spatiotemporal image correlation in routine fetal
echocardiography
Adapted from Ultrasound Obstet Gynecol2008; 31: 625–632
3 Feasibility of automated 3-dimensional fetal cardiac screening in 35
routine ultrasound practice
Adapted from J Ultrasound Med2009; 28: 881–888
4 Validation of volume measurements for fetal echocardiography using 49
four-dimensional ultrasound imaging and spatiotemporal image
correlation
Adapted from Ultrasound Obstet Gynecol2010; 35: 324-331
5 Reliability of fetal cardiac volumetry using spatiotemporal image 67
correlation assessment of in-vivoand in-vitromeasurements
Adapted from Ultrasound Obstet Gynecol2010; Sep; 36(3): 308-14
6 STIC Hallucinations. Gating artefacts in an in vitromodel 81
Submitted for publication
7 Fetal cardiac function assessed with four-dimensional ultrasound 91
imaging using spatiotemporal image correlation
Adapted from Ultrasound Obstet Gynecol2009; 33: 272–281
8 Assessment of fetal cardiac function, an overview 109
Submitted for publication
9 General discussion and future prospects 141
10 Summary 151
7
APPENDICES
1 Summary in Dutch 157
Samenvatting
2 Words of thanks in Dutch 163
Dankwoord
3 Curriculum Vitae 169
8 the fetal heart
9
Chapter 1
General introduction
10 the fetal heart