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The Chemical Biology of DNA Damage PDF

473 Pages·2010·6.844 MB·English
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by Nicholas E. Geacintov, Suse Broyde| 2010| 473 pages| 6.844| English

About The Chemical Biology of DNA Damage

Bringing the power of biochemical analysis to toxicology, this modern reference explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or organismic response. Clearly divided into two main sections, Part 1 focuses on selected examples of important DNA lesions and their biological impact, while the second part covers current advances in assessing and predicting the genotoxic effects of chemicals, taking into account the biological responses mediated by the DNA repair, replication and transcription machineries.A ready reference for biochemists, toxicologists, molecular and cell biologists, and geneticists seeking a better understanding of the impact of chemicals on human health.

Detailed Information

Author:Nicholas E. Geacintov, Suse Broyde
Publication Year:2010
ISBN:9783527322954
Pages:473
Language:English
File Size:6.844
Format:PDF
Price:FREE
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