Table Of ContentTHE BASAL GANGLIA V
ADVANCES IN BEHAVIORAL BIOLOGY
Editorial Board
Jan Bures Institute of Physiology, Prague, Czech Republic
Irwin Kopin National Institute of Mental Health, Bethesda, Maryland
Bruce McEwen Rockefeller University, New York, New York
James McGaugh University of California, Irvine, California
Karl Prlbram Stanford University School of Medicine, Stanford, California
Jay Rosenblatt Rutgers University, Newark, New Jersey
Lawrence Weiskrantz University of Oxford, Oxford, England
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Volume 37 KINDLING 4
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Volume 38A BASIC, CLINICAL AND THERAPEUTIC ASPECTS OF ALZHEIMER'S AND
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Volume 38B BASIC, CLINICAL AND THERAPEUTIC ASPECTS OF ALZHEIMER'S AND
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Edited by Giorgio Bernardi, Malcolm B. Carpenter, Gaetano Di Chiara,
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Volume 40 TREATMENT OF DEMENTIAS: A New Generation of Progress
Edited by Edwin M. Meyer, James W. Simpkins, Jyunji Yamamoto, and
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Volume 43 NEUROTRANSMITTERS IN THE HUMAN BRAIN
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Volume 44 ALZHEIMER'S AND PARKINSON'S DISEASES: Recent Developments
Edited by Israel Hanin, Mitsuo Yoshida, and Abraham Fisher
Volume 45 EPILEPSY AND THE CORPUS CALLOSUM 2
Edited by Alexander G. Reeves and David W. Roberts
Volume 46 BIOLOGY AND PHYSIOLOGY OF THE BLOOD-BRAIN BARRIER: Transport,
Cellular Interactions, and Brain Pathologies
Edited by Pierre-Olivier Couraud and Daniel Scherman
Volume 47 THE BASAL GANGLIA V
Edited by Chihiro Ohye, Minoru Kimura, and John S. McKenzie
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THE BASAL GANGLIA V
Edited by
Chihiro Ohye
Gunma University
Maebashi, Gunma, Japan
Minoru Kimura
Osaka University
Toyonaka, Osaka, Japan
and
John S. McKenzie
The University of Melbourne
Parkville, Victoria, Australia
SPRINGER SCIENCE+BUSINESS MEDIA, LLC
Llbrary of Congress Cataloglng-ln-Publlcatlon Data
The basal ganglla V I edlted by Chlhlro Ohye. Minoru Klmura. and John
S. McKenzie.
p. cm. -- (Advances in behavloral blology : v. 47)
"Proceedings of the Flfth Triennlal Meetlng of the International
Ba sa 1 Gangl ia Society. held May 23-26. 1995. in Ne.uno-Sato. Japan"
-T.p. verso.
Includes bibliographical references and index.
1. Basal ganglia--Physiology--Congresses. 2. Basal ganglia
-Diseases--Congresses. I. Ohye. Chihiro. II. Ki.ura. M. (Minoru).
1947- III. McKenzie. John S. IV. International Basal Ganglia
Society. Symposiu. (5th 1995 Nemuno-Sato. Hamajlma-cho. Japan)
V. Series.
[ONLM, 1. Basal Ganglia--physiology--congresses. 2. Basal Ganglia
Oiseases--physiopathology--congresses. W3 A0215 v.47 1996 I WL 307
B29717 19961
OP383.3.B353 1996
612.8·2--dc20
ONLM/OLC
for Library of Congress 96-34816
CIP
Proceedings of the Fifth Triennial Meeting of the International Basal Ganglia Society, held May
23-26,1995, in Nemuno-Sato, Japan
ISBN 978-1-4899-0196-5 ISBN 978-1-4899-0194-1 (eBook)
DOI 10.1007/978-1-4899-0194-1
© Springer Science+Business Media New York 1996
Originally published by Plenum Press, New York in 1996
Softcover reprint of the hardcover Ist edition 1996
1098765432 1
AII rights reserved
No part of this book may be reprocluced, stored in retrieval system, or transmitted in any form or
by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise,
without written permission from the Publisher
INTERNATIONAL BASAL GANGLIA SOCIETY (I BAGS)
OFFICERS (1992-1995)
PRESIDENT
Chihiro Ohye, Japan
PAST PRESIDENT
Gerard Percheron, France
PRESIDENT ELECT
Ann M. Graybiel, U.S.A.
SECRETARY
Minoru Kimura, Japan
TREASURER
Stephen T. Kitai, U.S.A.
COUNCIL
J. Paul Bolam, UK
Alexander R. Cools, The Netherlands
Alan R. Crossman, U.K.
Gaetano DiChiara, Italy
Richard L. Faull, New Zealand
Jean Feger, France
Michel Filion, Canada
Wolfram Schultz, Switzerland
HONORARY PRESIDENT
Hirotaro Narabayashi, Japan
LOCAL COMMITTEE
Program Okihide Hikosaka
Treasurer Masaya Segawa
Management Katsuma Nakano
Takashi Shibasaki
Masafumi Hirato
Masaru Matsumura
v
vi
IBAGS V
The Vth triennial meeting of the International Basal Ganglia Society was held at
Nemuno-sato,
Mie, Japan
May 23rd to 26th, 1995
Honorary President of the Meeting Hirotaro Narabayashi
Organizer, IBAGS President Chihiro Ohye
Secretary Minoru Kimura
Local committee
Program Okihide Hikosaka
Treasurer Masaya Segawa
Management Katsuma Nakano
Takashi Shibasaki
Masafumi Hirato
Masaru Matsumura
The following organizations and institutions are gratefully acknowledged:
Commemorative Association for the Japan World Exposition (1970)
The Pharmaceutical Manufacturers' Association of Tokyo
Osaka Pharmaceutical Manufacturers Association
Mie University International Exchange Fund
PREFACE
This volume, The Basal Ganglia V, is derived from proceedings of the fifth Triennial
Meeting of the International Basal Ganglia Society (IBAGS). The Meeting was held from
23-26 May, 1995, at Nemuno-Sato, in the Mie Prefecture of central Japan, not far from the
traditional birth place of the country. As at previous Meetings, our aim was to hear and discuss
new ideas and data on the Basal Ganglia. About one hundred papers were presented, on
platform or as posters. We had valuable talks, stimulating discussions, and agreeable social
contacts.
Although just before this Meeting, there were several unusual accidents in Japan, a
big earthquake in the Kobe area, not far from the Meeting place, and toxic gas terrorism in
Tokyo, some hundred participants came from Europe, the United States, and elsewhere. All
through the Meeting days, we were together in a beautiful environment, surrounded by fresh
green vegetation, flowers and blue sea, as has been traditional for IBAGS meetings. We spent
happy and pleasant sunny days there, with superb accommodation and cuisine.
Also following the traditional policy of our Society, this volume has been edited to
include as many papers as possible, without any selection. New ideas and data may
sometimes be controversial and still immature, but we accepted all and put them together in
this volume. We hope that from these fascinating papers, further new principles of basal
ganglia action might emerge in the future.
We are very much indebted to the excellent cooperation of all authors in sending their
papers in time, or almost in time, for the quick publication of this volume. And certainly, the
Editors are happy and proud ofthe fact that, with the great aid ofthe Publishers, we realized
the goal of distributing the volume within one year after the meeting. Such a quick
publication of the Proceedings is quite valuable in this era of day to day development of all
sciences, including Neuroscience of the Basal Ganglia. So please enjoy this volume, and get
new inspiration from it.
Chihiro Ohye
Minoru Kimura
John S. McKenzie
vii
CONTENTS
SECTION I. FUNCTIONAL CONNECTIVITY OF THE BASAL
GANGLIA
1. The Thalamostriatal Projection System in Rodents: A Single-Axon Labeling
Study... ... ...... ........ ... .. ... .. ... ... ... . . .... . ..... . . . .. 3
Andre Parent, Jacques Bourassa, and Martin Deschenes
2. Overlapping Striatal Distribution of Cortical Inputs from the Primary and
Supplementary Motor Areas in the Macaque Monkey . . . . . . . . . . . . . . . . .. 11
Masahiko Inase, Sharleen T. Sakai, and Jun Tanji
3. The Basal Ganglia-Thalamo-Cortical Connections with Special Reference to
Output Neuronal Distributions in Macaque Monkeys .................. 19
Katsuma Nakano, Tetsuro Kayahara, Hiroshi Ushiro, and
Hirofumi Kuwabara
4. Reversed Somatotopical Representations in the Subthalamic Nucleus as
Revealed by Cortical Inputs from the Primary Motor Cortex and the
Supplementary Motor Area . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 27
Atsushi Nambu, Masahiko Takada, Hironobu Tokuno, and Masahiko Inase
5. The Amygdalostriatal Projection: An Analysis of Synaptic Inputs to
GABAergic Interneuron Subtypes ................................. 33
Abbas F. Sadikot, Teresa M. Rudkin, and Yoland Smith
6. Branching Pattern and Geometrical Properties of Dendritic and Axonal
Arborizations in the Striato-Pallido-Thalamic System in Macaques ....... 43
Chantal Fran~ois, Jerome Yelnik, Patricia Arecchi-Bouchhioua, and
Gerard Percheron
7. The Relationships between Subthalamic Nucleus, Globus Pallidus and
Thalamic Parafascicular Nucleus: Getting Flaws in the Dual Circuit
Model ........................................................ 51
Jean Feger, Oum-Kaltoum Hassani and Mireille Mouroux
ix
x Contents
8. Anatomical Investigations of the Pallidotegmental Pathway in Monkey and
Man ......................................................... 59
David B. Rye, Robert S. Turner, Jerrold L. Vitek, Roy A. E. Bakay,
Michael D. Crutcher, and Mahlon R. DeLong
9. Two Pathways Between the Cortex and the Basal Ganglia Output Nuclei and
the Globus Pallidus ........... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 77
Hitoshi Kita
SECTION II. CHARACTERISTICS OF BASAL GANGLIA
NEURONS, TRANSMITTERS, AND MODULATORS
10. Protein Phosphatases Regulate CREB Phosphorylation and Fos Expression in
the Developing Striatum: Evidence and a Hypothesis . . . . . . . . . . . . . . . . .. 97
Fu-Chin Liu and Ann M. Graybiel
11. Behavioural and Biochemical Evidence that Cholinergic or Dopaminergic
Stimulation in the Nucleus Accumbens Differentially Alters
Dopaminergic Activities in Rat Ventrolateral Striatum ................. 105
Noriaki Koshikawa, Yukihiro Yoshida, Makiko Kitamura, Tadashi Saigusa,
and Alexander R. Cools
12. Patchy Distribution of Substance P Receptor Immunoreactivity in Developing
Rat Striatum ................................................... 113
Masahiko Takada, Hironobu Tokuno, Takeshi Kaneko, Ryuichi Shigemoto,
and Noboru Mizuno
13. The Role of Adenosine A Receptors in Regulating GABAergic Synaptic
2a
Transmission in Striatal Medium Spiny Neurons ...................... 119
Akihisa Mori, Tomomi Shindou, Michio Ichimura, Hiromi Nonaka, and
Hiroshi Kase
14. Dopaminergic Neurotransmission and Drug Withdrawal: Relevance to Drug
Craving ...................................................... 123
Marco Diana
15. The Membrane Potential in the Up State of Striatal Neurons is Determined by
Voltage-Activated Potassium Currents .............................. 131
C. J. Wilson and Y. Kawaguchi
16. Electrophysiblogical Consequences of D2 and/or D3 Receptor Knockout by
Antisense Oligonucleotides in Nigrostriatal Dopaminergic Neurons ...... 141
James M. Tepper, Bao-Cun Sun, L. P. Martin, and Ian Creese
17. Substance P Excites Large Aspiny Neurons of the Rat Neostriatum ........... 151
Toshihiko Aosaki and Yasuo Kawaguchi
18. Synaptic Plasticity in the Rat Neostriatum after Unilateral 6-Hydroxydopamine
Lesion of the Nigrostriatal Dopaminergic Pathway .................... 157
C. A. Ingham, S. H. Hood, P. Taggart, and G. W. Arbuthnott
