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The Aptamer Handbook: Functional Oligonucleotides and Their Applications PDF

520 Pages·2006·4.353 MB·English
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by Sven Klussmann| 2006| 520 pages| 4.353| English

About The Aptamer Handbook: Functional Oligonucleotides and Their Applications

In The Aptamer Handbook, leading scientists from academia as well as biotech and pharma companies introduce the revolutionary concept of designing RNA and DNA oligonucleotides with novel functions by in vitro selection. These functions comprise high affinity binding (aptamers), catalytic activity (ribozymes and deoxyribozymes) or combinations of binding and catalytic properties (aptazymes).Basic concepts and technologies describing in detail how these functional oligonucleotides can be identified are presented. Numerous examples demonstrate the versatility of in vitro selected oligonucleotides. Special emphasis has been put on a section that shows the broad applicability of aptamers, e. g. in target validation, for analytics, or as new therapeutics.This first overview in the field is of prime interest for a broad audience of scientists both in academia and in industry who wish to expand their knowledge on the potential of new oligonucleotide functions and their applications.

Detailed Information

Author:Sven Klussmann
Publication Year:2006
ISBN:9783527310593
Pages:520
Language:English
File Size:4.353
Format:PDF
Price:FREE
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