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The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development (Wiley Series on Technologies for the Pharmaceutical Industry) PDF

281 Pages·2010·20.619 MB·English
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by Michael J. Rosenberg| 2010| 281 pages| 20.619| English

About The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development (Wiley Series on Technologies for the Pharmaceutical Industry)

Apply adaptive research to improve results in drug developmentThe pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently.With a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current practices, and the advantages of adaptive research technology and methods. He explains the concepts, principles, and specific techniques of adaptive research, and demonstrates why it is an essential evolutionary step toward improving drug research and development.Chapters explore such subjects as:The adaptive conceptDesign and operational adaptationsSample-size reestimationAgile clinical developmentSafety and dose findingStatistics in adaptive research, including frequentist and Bayesian approachesData management technologiesThe future of clinical developmentBy combining centuries-old intellectual foundations, recent technological advances, and modern management techniques, adaptive research preserves the integrity and validity of clinical research but dramatically improves efficiency.

Detailed Information

Author:Michael J. Rosenberg
Publication Year:2010
ISBN:9780470247518
Pages:281
Language:English
File Size:20.619
Format:PDF
Price:FREE
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