The Adhesive Interaction of Cells

428 Pages·1999·7.07 MB·English

by  E. Edward Bittar

ADVANCES IN
MOLECULAR AND
CELL BIOLOGY
Volume 28 1999
THE ADHESIVE INTERACTION OF CELLS
This Page Intentionally Left Blank
ADVANCES IN
MOLECULAR AND
CELL BIOLOGY
THE ADHESIVE INTERACTION OF CELLS
Series Editor: E. EDWARD BITTAR
Department of Physiology
University of Wisconsin-Madison
Madison, Wisconsin
Guest Editors: DAVID R. GARROD
ALISON J. NORTH
X~ARTYN
A.J. CHIDGEY
School of Biological Sciences
University of Manchester
Manchester, England
VOLUME 28 1999
@
JAl PRESS INC.
Stamford, Connecticut
Copyright 0 1999lAl PRfSS INC.
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Stamford, Connecticut 06907
All rights reserved. No part of this publication may be reproduced, stored on a retrieval
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recording, filming or othenvise without prior permission in writing from the publisher.
ISBN: 0-7623-0495-2
Manufactured in the United States of America
CONTENTS
LIST OF CONTRIBUTORS vii
PREFACE
David R. Carrod xi
PART 1. ADHESION MOLECULES AND THEIR LIGANDS
THE MOLECULAR ANATOMY OF INTEGRINS
Linda 1. Green and Martin 1. Humphries 3
THE CADHERIN SUPERFAMILY
Jorg Stappert and Rolf Kemler 27
THE SELECTINS AND THEIR LIGANDS:
ADHESION MOLECULES OF THE VASCULATURE
Thomas F. Tedder, Xuan Li, and Douglas A. Steeber 65
THE IMMUNOGLOBULIN SUPERFAMILY
David 1. Simmons 113
PART II. ORGANIZATION OF ADHESION COMPLEXES
FOCAL ADHESIONS AND ADHERENS JUNCTIONS:
THEIR ROLE IN TUMORIGENESIS
Avri Ben-Ze’ev 135
DESMOSOMAL ADHESION
David R. Carrod, Chris Tselepis, Sarah K. Runswick,
Alison J. North, Sarah R. Wallis, and Martyn A.J. Chidggey 165
V
vi CONTENTS
THE MOLECULAR BASIS FOR THE STRUCTURE, FUNCTION,
AND REGULATION OF TIGHT JUNCTIONS
Sandra Citi and Michelangelo Cordenonsi 203
PART 111. SIGNALING BY ADHESION MOLECULES
ACTIVATION OF INTEGRIN SIGNALING PATHWAYS BY
CELL INTERACTIONS WITH EXTRACELLULAR MATRIX
Cwynneth M. Edwards and Charles H. Streuli 237
SIGNALING AND PLATELET ADHESION
Xiaoping Du and Mark H. Cinsberg 269
SIGNALING BY CELL ADHESION MOLECULES
IN THE NERVOUS SYSTEM
john j. Hernperly 303
PART IV. ADHESIVE PROCESSES
VASCULAR ENDOTHELIAL CELL ADHESION MOLECULES
AND THE CONTROL OF LEUKOCYTE TRAFFIC IN
CUTAN EOUS IN F LAMMATION
Dorian 0.H askard, lustin C. Mason, and lulie McHale 323
THE ROLE OF ADHESION IN METASTASIS: POTENTIAL
MECHANISMS AND MODULATION OF INTEGRIN ACTIVITY
john F. Marshall and Ian R. Hart 345
INTEGRIN ADHESION IN CELL MIGRATION
Sean P. Palecek, Elisabeth A. Cox, Anna Huttenlocher,
Douglas A. Lauffenburger, and Alan F. Horwitz 367
ADHESION RECEPTORS: CRITICAL EFFECTORS OF
TROPHOB LAST DI FF E RE NTIA T ION DU RIN G
IM PLANTATI0 N AN D PLACE NTATl 0N
Caroline H. Darnsky, Yan Zhou, Olga Cenbacev,
lay Cross, and Susan I. Fisher 389
INDEX 409
LIST OF CONTRIBUTORS
Avri Ben-Ze'ev Department of Molecular Cell Biology
Weizmann institute of Science
Rehovot, Israel
Martyn A,]. Chidgey Division of Medical Sciences
University of Birmingham
Queen Elizabeth Hospital
Birmingham, England
Sandra Citi Dipartimento di Biologia
University of Padova
Padova, Italy
Michelangelo Cordenonsi Dipartimento di Biologia
University of Padova
Padova, Italy
Elisabeth A. Cox Department of Cell and Structural Biology
University of Illinois at Urbana-Champaign
Urhana. Illinois
Jay Cross Samuel Lunenfeld Research Center
Mount Sinai Hospital
Toronto, Canada
Caroline H. Damsky Department of Stoinatology
University of California
San Francisco, California
Xiaoping Du Department of Pharmacology
University of Illinois
Chicago, I I I in o is
vii
...
Vill LIST OF CONTRIBUTORS
Cwynneth M. Edwards School of Biological Sciences
University of Manchester
Manchester, England
Susan 1. Fisher Department of Stomatology
University of California
San Francisco, California
David R. Carrod School of Biological Sciences
University of Manchester
Manchester, England
Olga Cenbacev Department of Stomatology
University of California
San Francisco, California
Mark H. Cinsberg Department of Vascular Biology
Scripps Research Institute
La Jolla, California
Linda 1. Green School of Biological Sciences
University of Manchester
Manchester, England
Ian R. Hart Richard Dimbleby Department of Cancer
ResearchKRF
St. Thomas’ Hospital
London, England
Dorian 0. Haskard National Heart and Lung Institute
Imperial College School of Medicine at
Hammersmith Hospital
London, England
John I. Hemperly Becton Dickinson Research Center
Research Triangle Park, North Carolina
Alan F. Honvitz Department of Cell and Structural Biology
University of Illinois at Urbana-Champaign
Urbana, Illinois
Martin J. Humphries School of Biological Sciences
University of Manchester
Manchester, England
List of Contributors ix
Anna Huttenlocher Department of Cell and Structural Biology
University of Illinois at Urbana-Champaign
Urbana, Illinois
Rolf Kernler Max-Planck institute fur lmrnunobiologie
Frieburg, Germany
Douglas A. Lauffenburger Department of Chemical Engineering
Massachusetts Institute of Technology
Cambridge, Massachusetts
Xuan Li Department of Immunology
Duke University Medical Center
Durham, North Carolina
lustin C. Mason National Heart and Lung Institute
Imperial College School of Medicine at
Hammersmith Hospital
London, England
john F. Marshall Richard Dimbleby Department of Cancer
ResearchKRF
St. Thomas’ Hospital
London, England
lulie McHale National Heart and Lung Institute
Imperial College School of Medicine at
Hammersmith Hospital
London, England
Alison 1. North School of Biological Sciences
University of Manchester
Manchester, England
Sean P. Palecek Department of Chemical Engineering
Massachusetts Institute of Technology
Cambridge, Massachusetts
Sarah K. Runswick School of Biological Sciences
University of Manchester
Manchester, England
David 1. Simmons Department of Neurosciences
SmithKline Beecharn
New Harlow, Essex, England