Table Of ContentJames Goh · Chwee Teck Lim
Hwa Liang Leo (Eds.)
Volume 61
The 17th International
Conference on Biomedical
Engineering
ICBME 2016, 7th to 10th December 2016,
Singapore
IFMBE Proceedings
Volume 61
Series editor
Ratko Magjarevic
Deputy Editors
Fatimah Ibrahim
Igor Lacković
Piotr Ładyżyński
Emilio Sacristan Rock
The International Federation for Medical and Biological Engineering, IFMBE, is a federation of national and transnational
organizations representing internationally the interests of medical and biological engineering and sciences. The IFMBE is a
non-profitorganizationfosteringthecreation,disseminationandapplicationofmedicalandbiologicalengineeringknowledge
andthemanagementoftechnologyforimprovedhealthandqualityoflife.Itsactivitiesincludeparticipationintheformulation
of public policy and the dissemination of information through publications and forums. Within the field of medical, clinical,
and biological engineering, IFMBE’s aims are to encourage research and the application of knowledge, and to disseminate
information and promote collaboration. The objectives of the IFMBE are scientific, technological, literary, and educational.
TheIFMBEisaWHOaccreditedNGOcoveringthefullrangeofbiomedicalandclinicalengineering,healthcare, healthcare
technology and management. It is representing through its 60 member societies some 120.000 professionals involved in the
various issues of improved health and health care delivery.
IFMBE Officers
President: James Goh, Vice-President: Shankhar M. Krishnan
Past President: Ratko Magjarevic
Treasurer: Marc Nyssen, Secretary-General: Kang Ping LIN
http://www.ifmbe.org
More information about this series at http://www.springer.com/series/7403
James Goh Chwee Teck Lim
(cid:129)
Hwa Liang Leo (Eds.)
The 17th International Conference
on Biomedical Engineering
ICBME 2016, 7th to 10th December 2016, Singapore
123
Editors
James Goh HwaLiang Leo
Department ofBiomedical Engineering Department ofBiomedical Engineering
National University ofSingapore National University ofSingapore
Singapore Singapore
ChweeTeck Lim
Department ofBiomedical Engineering
National University ofSingapore
Singapore
ISSN 1680-0737 ISSN 1433-9277 (electronic)
IFMBE Proceedings
ISBN 978-981-10-4219-5 ISBN978-981-10-4220-1 (eBook)
DOI 10.1007/978-981-10-4220-1
LibraryofCongressControlNumber:2017935840
©SpringerNatureSingaporePteLtd.2017
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Preface
TheInternationalConferenceonBiomedicalEngineeringisaseriesofinternationalconferenceinbiomedicalengineeringheld
in Singapore and is jointly organised by the Faculty of Engineering of the National University of Singapore (NUS) and the
Biomedical Engineering Society (Singapore) (BES). The objective of ICBME 2016, held from 7 – 10 December, was to
providelocalandinternationalparticipantsaninvaluableopportunitytostaycurrentonthelatestscientificdevelopmentsand
emerging challenges of the biomedical engineering field.
Biomedicalengineeringisappliedinmostaspectsofourhealthcareecosystem.Fromelectronichealthrecordstodiagnostic
tools to therapeutic, rehabilitative and regenerative treatments, the work of biomedical engineers is evident. Biomedical
engineers work at the intersection of engineering, life sciences and healthcare. The engineers would use principles from
appliedscienceincludingmechanical,electrical,chemicalandcomputerengineeringtogetherwithphysicalsciencesincluding
physics,chemistryandmathematicstoapplythemtobiologyandmedicine.Applyingsuchconceptstothehumanbodyisvery
much the same concepts that go into building and programming a machine. The goal is to better understand, replace or fix a
target system to ultimately improve the quality of healthcare.
ICBME 2016 received some 350 abstracts from 25 countries and the programme featured more than 120 speakers who
spoke on new research and developments in six themes including BioImaging and BioSignals, Bio-Micro/Nanotechnologies,
BioRobotics and Medical Devices, Biomaterials and Regenerative Medicine, BioMechanics and Mechanobiology,
Engineering/Synthetic Biology across the four-day programme comprising 60 sessions.
SpecialsessionsincludedthetopicsofAdvancesinMicrofluidicsandNanofluidics,BioelectronicDevices,Bioengineering
the Heart, Bioimaging, Biomedical Engineering/Clinical Engineering, Biomedical Nanotechnology, Cardiovascular Flows,
EngineeringBiology/SyntheticBiology,FlexibleandWearableTechnologies,HealthInformatics,IFMBEHealthTechnology
Assessment, Integrated Nano-biomechanics: Biological Flow, Mechanobiology, Rehabilitation Robotics, Stem Cells and
Organs-on-Chips, Surgical Robotics and Navigation.
The programme was also headlined by seven plenary lectures which include “Cell Therapy of Diabetes Mellitus and its
Complications: How Far are we?” by Bernat Soria Escoms, “Bio-integrated and Bio-inspired Stretchable Electronics” by
Yonggang Huang, “Recent Advances on Nature Inspired Tissue Engineering Approaches for the Regeneration of Different
Tissues”byRuiL.Reis,“InnovativeHealthcareisinthePalmofyourHand”byLukeLee,“DropletMicrofluidicsforSingle
CellStudies”byDavidA.Weitz,“MakingMRISafeforImplantedDevices”byJohnM.Pauly,and“NeedDrivenInnovation
in Medical Technology: From I to I” by Lawrence Ho.
ICBMEhasattractedagreaternumberofparticipantsoneveryoccasionthatithasmetandweareproudtohavereceived
thecontinuedendorsementofInternationalFederationforMedicalandBiologicalEngineering(IFMBE)andforthefirsttime,
theendorsementoftheAgencyforScience,TechnologyandResearch(A*STAR),aswellasthoseofmanylocalandregional
societies.Their supportisatestamenttothequalityoftheconferenceandwe areheartened tohavetheparticipation froman
impressive roster of highly respected and internationally renowned speakers to lead the programme. The faculty represented
theregion’sbestofbiomedicalengineeringandwehopeithasprovidedanexcellentopportunityforourfellowcolleaguesto
contribute research and to keep abreast of the exciting developments in our field.
February 2017 Prof. James GOH
Chairman
Prof. Chwee Teck LIM
Scientific Programme Chair
Assoc. Prof. Hwa Liang LEO
Scientific Programme Co-Chair
16th ICBME Organising Committee
Acknowledgements
Organised by
National University of Singapore
Biomedical Engineering Society (Singapore)
Supporting Partners
Agency for Science, Technology and Research
IFMBE
Supporting Organizations
Biomedical Engineering Society
Consortium for Medical Device Technologies
The Korean Society of Medical & Biological Engineering
VIII Acknowledgements
The Institution of Engineers Singapore
Society for Biomaterials
Springer
Sponsored by
AIP Publishing
Supporting Media
Bioengineering
Organization
Organising Committee
Chairperson James Goh
Co-chair & Treasurer Siew Lok Toh
Scientific Programme Chair Chwee Teck Lim
Scientific Programme Co-chair Hwa Liang Leo
International Advisory Panel
Kai-Nan An Mayo Clinic
Dominique Barthes-Biesel Université de Technologie de Compiegne
Shu Chien University of California San Diego
Yubo Fan Beihang University
Jing Fang Peking University
Benny Geiger Weizmann Institute of Science
Peter Hunter University of Auckland
Zhonglai Jiang Shanghai Jiao Tong University
Roger Kamm Massachusetts Institute of Technology
Andrew F. Laine Columbia University
Mark Pearcy Queensland University of Technology
Fong-Chin Su National Cheng Kung University
Geert Schmid-Schobein University of California San Diego
David F. Williams Wake Forest Institute of Regenerative Medicine
Takami Yamaguchi Tohoku University
International Scientific Committee
Taiji Adachi Kyoto University
Gang Bao Rice University
Rashid Bashir University of Illinois Urbana-Champaign
Markus J. Buehler Massachusetts Institute of Technology
Anthony M.J. Bull Imperial College London
Hsueh-Chia Chang University of Notre Dame
Cheng-Kung Cheng National Yang Ming University
Mian Long Institute of Mechanics, Chinese Academy of Sciences
Nigel Lovell University of New South Wales
Ratko Magjarević University of Zagreb
Takeo Matsumoto Nagoya University
Josep Samitier Institute for Bioengineering of Catalonia
Karol Miller University of Western Australia
Arthur Mak Chinese University of Hong Kong
Dennis Discher University of Pennsylvania
David Elad Tel Aviv University
C. Ross Ethier Georgia Institute of Technology
Shih-Kang Fan National Taiwan University
Huajian Gao Brown University
X Organization
Amit Gefen Tel Aviv University
Guy Genin Washington University in St. Louis
J. Justin Gooding University of New South Wales
Farshid Guilak Washington University in St. Louis
X. Ed Guo Columbia University
Walter Herzog University of Calgary
Gerhard Holzapfel Graz University of Technology
Dean Ho University of California Los Angeles
I-Ming Hsing Hong Kong University of Science and Technology
Fatimah Binti Ibrahim University of Malaya
Takuji Ishikawa Tohoku University
Noo Li Jeon Seoul National University
Michael Khoo University of Southern California
Eng Hin Lee National University of Singapore
Sang-Hoon Lee Korea University
Marcus Pandy University of Melbourne
Heinz Redl Ludwig Boltzmann Institute of Experimental and Clinical Traumatology
Robert O. Ritchie University of California Berkeley
John A. Rogers University of Illinois Urbana-Champaign
Masaaki Sato Tohoku University
Masahiro Sokabe Nagoya University
Joachim P. Spatz University of Heidelberg
Masao Tanaka Osaka University
Ichiro Sakuma University of Tokyo
Sehyun Shin Korea University
Jackrit Suthakom Mahidol University
Nitish Thakor National University of Singapore
David W. Townsend A*STAR-NUS Clinical Imaging Research Centre
Herbert Voigt Boston University
Shigeo Wada Osaka University
Jaw-Lin Wang National Taiwan University
David A. Weitz Harvard University
Ed X. Wu Hong Kong University
Chaoyong Yang Xiamen University
Guang-Zhong Yang Imperial College London
Kam Leong Columbia University
Feng-Huei Lin National Taiwan University
Kang-Ping Lin Chung Yuan Christian University
Hao Liu Chiba University
Ajit Yoganathan Georgia Institute of Technology
Sun Yu University of Toronto
Haishan Zeng University of British Columbia
Local Scientific Committee
Scientific Programme Chair
Chwee Teck Lim National University of Singapore
Scientific Programme Co-chair
Hwa Liang Leo National University of Singapore
