Textbook of Immunology

286 Pages·2014·28.529 MB·English

by  Sunil Kumar Mohanty, K. Sai Leela, K. C. Nathsarma

Textbook of
Immunology

Textbook of
Immunology
Second Edition
Sunil Kumar Mohanty MD
Professor and Head
Department of Microbiology
Kalinga Institute of Medical Sciences
Bhubaneswar, Odisha, India
K Sai Leela MD
Professor
Department of Microbiology
Kamineni Institute of Medical Sciences
Narketpally, Nalgonda, Andhra Pradesh, India
Foreword
KC Nathsarma
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Textbook of Immunology
First Edition: 2007
Second Edition: 2014
ISBN 978-93-5090-474-9
Printed at
Dedicated to
The loving memory of my colleague
Late Dr Subrat Mishra
whose inspiration and encouragement
prompted me to write a book on immunology
—Sunil Kumar Mohanty
The teachers and the taught
—K Sai Leela

Foreword
It is my immense pleasure to write the foreword to the Textbook of Immunology authored by
Dr Sunil Kumar Mohanty and Dr K Sai Leela.
The immunology as a subject has grown immensely in the last 50 years. The amount of detail
knowledge that has been accumulated has already reached paroxysmal proportion. If there has
been a remarkable progress, then it is in the domain vaccinology, which led to the control of
a number of infectious diseases. But, there remains a crying need for vaccine against others.
It is hoped that the immunologists of today, using the tools of molecular and cellular biology,
genomics, and proteonomics will make inroads in preventing these diseases. Presently, the
immunodiagnostic measures are of great utility in diagnosis and monitoring the treatment of
various diseases. The Textbook of Immunology serves a great purpose not only in understanding
the fundamentals of immunology but also to delve into the depth to explore the fascinating
aspects of the immune system, that will make them doctors, researchers and teachers. Very few
books are complete in all aspects.
The authors have made every effort to present the text in a lucid and readable style with
illustrative graphics and colored diagrams without sacrificing the important details.
I congratulate the authors for the compendium, which is bound to be of great interest and
utility for students, researchers, teachers and doctors of medical and other allied sciences.

KC Nathsarma md (New Zealand)
Ex-Professor and Head
Department of Microbiology
MKCG Medical College
Cuttack, Odisha, India

Preface to the Second Edition
The goals for the second edition of Textbook of Immunology have remained the same as those
of the first edition published in 2007 to provide a brief, accurate and updated presentation of
those aspects of immunology that are of particular significance in the fields of clinical infections,
diagnostic immunology, vaccinology, transplantation immunology and in other allied fields of
biological sciences.
In the last few years, we have received certain comments from our readers, expressing
satisfaction on some parameters and also pointing out certain inadequacies. We acknowledge
their inputs with humility and utmost respect and have acted on the shortcomings meticulously
in the second edition of Textbook of Immunology.
Initially, the book was designed, mainly, for the use of undergraduate students. Therefore, we
stressed more on basics than going deeply into the intricacy.
In honoring the recommendation of a number of learned teachers, in the fields of immunology,
we have not only included certain topics such as HIV infection (AIDS), immunology of fungal
infections, etc. but also updated the knowledge on various subjects such as antigen receptors,
cytokines, their receptors and future prospects, ‘B’ cell and ‘T’ cell repertoires, autoimmune disease,
etc. Almost in every chapter, there has been addition, deletion and correction of inadvertent
errors without compromising the lucidity, clarity and consistency. We have also included some
more figures and tables wherever required.
Perfection is too vast for comprehension. But striving for perfection is the triumph of human
intelligence. We have worked hard to minimize the shortcomings. However, we fervently desire
to get the regular inputs from our readers to smoothen the angularities.
We have consulted friends, especially, Dr SS Mishra, Professor of Pharmacology; Dr Shruti
Mohanty, Professor of Biochemistry, and colleagues with relevant expertise to advise us and to
those we owe our sincere gratitude.
We hope that the second (revised) edition of Textbook of Immunology will invite today’s
students not only to acquire familiarity but also to delve into the depth to explore the fascinating
aspects of the immune system, that will make them doctors, researchers and teachers.
Sunil Kumar Mohanty
K Sai Leela