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Telomerase: Composition, Functions, and Clinical Implications PDF

172 Pages·2014·2.1 MB·English
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by Aiden N Gagnon| 2014| 172 pages| 2.1| English

About Telomerase: Composition, Functions, and Clinical Implications

Telomerase is a ribonucleoprotein enzyme that catalyzes the cellular synthesis of telomeric DNA during cellular division resulting in maintenance of telomere length and increased proliferative potential Several studies suggest that the telomerase may play an important role in the diagnosis and prognosis of cancer because its expression strongly correlates with the potential tumor progression Ninety percent of human cancers on different organs have shown high telomerasa activity This book reviews research in the field of telomerase including functions of telomerase independent of its interaction with telomeres on gene expression and chromatin structure histone deacetylase inhibition as an anticancer telomerase targeting strategy and others

Detailed Information

Author:Aiden N Gagnon
Publication Year:2014
ISBN:9781617283390
Pages:172
Language:English
File Size:2.1
Format:PDF
Price:FREE
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