Table Of ContentAdvances in Experimental Medicine and Biology 1142
Qing Yang
Tamo Fukamizo Editors
Targeting
Chitin-
containing
Organisms
Advances in Experimental Medicine and Biology
Volume 1142
Editorial Board
IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel
ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research,
Orangeburg, NY, USA
JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA
RODOLFO PAOLETTI, University of Milan, Milan, Italy
NIMA REZAEI, Children’s Medical Center Hospital, Tehran University
of Medical Sciences, Tehran, Iran
More information about this series at http://www.springer.com/series/5584
Qing Yang Tamo Fukamizo
(cid:129)
Editors
Targeting Chitin-containing
Organisms
123
Editors
QingYang TamoFukamizo
State Laboratory of Biology for Plant Biochemistry−Electrochemistry Research
Diseases andInsect Pests Unit, Institute of Science
Institute of Plant Protection at Chinese Suranaree University of Technology
Academy of Agricultural Sciences Nakhon Ratchasima, Thailand
Beijing,China
Schoolof Bioengineering
DalianUniversity ofTechnology
Dalian, China
ISSN 0065-2598 ISSN 2214-8019 (electronic)
Advances in Experimental Medicine andBiology
ISBN978-981-13-7317-6 ISBN978-981-13-7318-3 (eBook)
https://doi.org/10.1007/978-981-13-7318-3
©SpringerNatureSingaporePteLtd.2019
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Contents
1 An Introduction to the Book. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Qing Yang and Tamo Fukamizo
2 Chitin: Structure, Chemistry and Biology. . . . . . . . . . . . . . . . . . . . 5
Bernard Moussian
3 Chitin Prevalence and Function in Bacteria, Fungi
and Protists. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Lea Steinfeld, Ali Vafaei, Janin Rösner and Hans Merzendorfer
4 ImmuneResponsesofMammalsandPlantstoChitin-Containing
Pathogens . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
Xi Jiang, Han Bao, Hans Merzendorfer and Qing Yang
5 Chitin Organizing and Modifying Enzymes and Proteins
Involved In Remodeling of the Insect Cuticle . . . . . . . . . . . . . . . . . 83
SubbaratnamMuthukrishnan,HansMerzendorfer,YasuyukiArakane
and Qing Yang
6 Chitin-Active Lytic Polysaccharide Monooxygenases . . . . . . . . . . . 115
Gaston Courtade and Finn L. Aachmann
7 Bacterial Chitinase System as a Model of Chitin
Biodegradation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131
Takafumi Itoh and Hisashi Kimoto
8 Chitin Synthesis and Degradation in Fungi:
Biology and Enzymes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153
Jinkui Yang and Ke-Qin Zhang
9 Chitin in Arthropods: Biosynthesis, Modification,
and Metabolism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169
Xiaojian Liu, Jianzhen Zhang and Kun Yan Zhu
v
vi Contents
10 Nematode Chitin and Application. . . . . . . . . . . . . . . . . . . . . . . . . . 209
Qi Chen and Deliang Peng
11 Human Chitinases: Structure, Function, and Inhibitor
Discovery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221
Ashutosh Kumar and Kam Y. J. Zhang
12 Chitin/Chitosan-Active Enzymes Involved in Plant–Microbe
Interactions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253
Tamo Fukamizo and S. Shinya
13 Chitinous Structures as Potential Targets for Insect
Pest Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273
Guillaume Tetreau and Ping Wang
Contributors
Finn L. Aachmann DepartmentofBiotechnologyandFood Science, NOBIPOL,
NTNU Norwegian University of Science and Technology, Trondheim, Norway
Yasuyuki Arakane Department of Applied Biology, Chonnam National
University, Gwangju, South Korea
Han Bao School of Bioengineering, Dalian University of Technology, Dalian,
China
QiChen InstituteofPlantProtection,ChineseAcademyofAgriculturalSciences,
Beijing, China
Gaston Courtade Department of Biotechnology and Food Science, NOBIPOL,
NTNU Norwegian University of Science and Technology, Trondheim, Norway
Tamo Fukamizo Biochemistry-Electrochemistry Research Unit, School of
Chemistry, Suranaree University of Technology, Nakhon Ratchasima, Thailand
Takafumi Itoh Faculty of Bioscience and Biotechnology, Fukui Prefectural
University, Eiheiji-cho, Yoshida-gun, Fukui, Japan
Xi Jiang School of Bioengineering, Dalian University of Technology, Dalian,
China
Hisashi Kimoto Faculty of Bioscience and Biotechnology, Fukui Prefectural
University, Eiheiji-cho, Yoshida-gun, Fukui, Japan
Ashutosh Kumar Laboratory for Structural Bioinformatics, Center for
Biosystems Dynamics Research, RIKEN, Tsurumi, Yokohama, Kanagawa, Japan
Xiaojian Liu Research Institute of Applied Biology, Shanxi University, Taiyuan,
Shanxi, China
HansMerzendorfer DepartmentofChemistryandBiology–MolecularBiology,
University of Siegen, Siegen, Germany;
Institute of Biology, University of Siegen, Siegen, Germany
vii
viii Contributors
Bernard Moussian Université Côte d’Azur, CNRS, Inserm, Institute of Biology
Valrose, Parc Valrose, Nice, France
Subbaratnam Muthukrishnan Department of Biochemistry and Molecular
Biophysics, Kansas State University, Manhattan, KS, USA
Deliang Peng Institute of Plant Protection, Chinese Academy of Agricultural
Sciences, Beijing, China
Janin Rösner Department of Chemistry and Biology – Molecular Biology,
University of Siegen, Siegen, Germany
S. Shinya Laboratory of Molecular Biophysics, Institute of Protein Research,
Osaka University, Osaka, Japan
Lea Steinfeld Department of Chemistry and Biology – Molecular Biology,
University of Siegen, Siegen, Germany
Guillaume Tetreau University of Grenoble Alpes, CNRS, CEA, IBS, Grenoble,
France
AliVafaei DepartmentofChemistryandBiology–MolecularBiology,University
of Siegen, Siegen, Germany
Ping Wang Department of Entomology, Cornell University, Geneva, NY, USA
Jinkui Yang State Key Laboratory for Conservation and Utilization of
Bio-Resources in Yunnan, and Key Laboratory for Microbial Resources of the
Ministry of Education, Yunnan University, Kunming, Yunnan, China
Qing Yang State Laboratory of Biology for Plant Diseases and Insect Pests,
InstituteofPlantProtectionatChineseAcademyofAgriculturalSciences,Beijing,
China;
School of Bioengineering, Dalian University of Technology, Dalian, China
Jianzhen Zhang Research Institute of Applied Biology, Shanxi University,
Taiyuan, Shanxi, China
Kam Y. J. Zhang Laboratory for Structural Bioinformatics, Center for
Biosystems Dynamics Research, RIKEN, Tsurumi, Yokohama, Kanagawa, Japan
Ke-Qin Zhang State Key Laboratory for Conservation and Utilization of
Bio-Resources in Yunnan, and Key Laboratory for Microbial Resources of the
Ministry of Education, Yunnan University, Kunming, Yunnan, China
Kun Yan Zhu Department of Entomology, Kansas State University, Manhattan,
KS, USA
Chapter 1
An Introduction to the Book
Qing Yang and Tamo Fukamizo
Abstract Chitin is a linear biopolymer composed of b-1,4-linked N-acet-
ylglucosamine(GlcNAc),andanessentialcomponentinexoskeletonofinsectsand
crustaceans, the egg shells of parasitic nematodes, and the fungal cell wall. Since
the chitin-containing organisms often threaten human health, food safety, and
agricultural production, it has been highly desirable to control the hazardous
chitin-containing organisms. This book will provide researchers and students with
information on the recent research progress about the biology of chitin-containing
organisms and their cross-talk with other organisms. This book also contains
essentialknowledgeofdrugdesignforcontrollingchitin-containingorganisms.The
authors deeply hope this book brings more attention to the fascinating yet unex-
ploited world of chitin. We would like to thank all contributors for their expertise
and generous support.
(cid:1) (cid:1) (cid:1) (cid:1)
Keywords Chitin Structure remodeling Biodegradation Cross-talk Drug
design
This book contains comprehensive contributions to chitin biology and
chitin-metabolism-related enzymes. Chitin, the second most abundant biopolymer
next to cellulose in nature, is a linear biopolymer composed of b-1,4-linked
N-acetylglucosamine (GlcNAc) (Chap. 2), and an essential component in
Q.Yang(&)
StateLaboratoryofBiologyforPlantDiseasesandInsectPests,
InstituteofPlantProtectionatChineseAcademyofAgriculturalSciences,
No.2YuanmingyuanWestRoad,Beijing100193,China
e-mail:[email protected]
SchoolofBioengineering,DalianUniversityofTechnology,No.2LinggongRoad,
Dalian116023,China
T.Fukamizo
Biochemistry-ElectrochemistryResearchUnit,SchoolofChemistry,
SuranareeUniversityofTechnology,111,UniversityAvenue,MuangDistrict,
NakhonRatchasima30000,Thailand
e-mail:[email protected]
©SpringerNatureSingaporePteLtd.2019 1
Q.YangandT.Fukamizo(eds.),TargetingChitin-containing
Organisms,AdvancesinExperimentalMedicineandBiology1142,
https://doi.org/10.1007/978-981-13-7318-3_1
