Tarek Ahmed bw.indd

218 Pages·2011·1.71 MB·English

Innovative therapies for optimizing
outcomes of coronary artery disease
Tarek A.N. Ahmed
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The studies described in this thesis were performed at the department of Cardiology of the
Leiden University Medical Center, Leiden, the Netherlands.
Copyright © 2011 Tarek A.N. Ahmed, Leiden, the Netherlands. All rights reserved. No part
of this book may be reproduced or transmitted in any form or by any means, without prior
written permission of the author.
Layout and printing: Optima Grafi sche Communicatie, Rotterdam, the Netherlands
ISBN: 978-94-6169-183-5
Financial support to the costs associated with the publication of this thesis from the depart-
ment of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
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Innovative therapies for optimizing
outcomes of coronary artery disease
PROEFSCHRIFT
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van de Rector Magnifi cus prof. mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties
te verdedigen op donderdag 15 December 2011
klokke 15:00 uur
door
Tarek Abdel-Hameed Nagib Ahmed
Geboren te Asyut, Egypte
1976
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PROMOTIECOMMISSIE
Promotors: Prof. Dr. J.W.Jukema
Prof. Dr. M.J.Schalij
Overige leden: Prof. Dr. E.E. van der Wall
Prof. Dr. A. van der Laarse
Dr. H.F. Verwey
Dr. B.L. van der Hoeven
Dr. S.A.M. Said, Ziekenhuis Groep Twente, Hengelo
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To Heba and Ayah
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CONTENTS OF THE THESIS
Chapter 1: General introduction and outline of the thesis. 9
Chapter 2: Aspiration thrombectomy during primary percutaneous coronary inter- 27
vention as adjunctive therapy to early (in-ambulance) abciximab administration in
patients with acute ST elevation myocardial infarction: An analysis from Leiden MIS-
SION! Acute Myocardial Infarction Treatment Optimization Program.
Journal of Interventional Cardiology 2011 Nov 8 [Epub ahead of print]
Chapter 3: Pre-infarction angina predicts thrombus burden in patients admitted for 47
ST-segment elevation myocardial infarction.
Submitted for publication
Chapter 4: Clinical performance of drug eluting stents with Biodegradable polymeric 67
coating, a meta-analysis and systematic review.
EuroIntervention 2011; Aug; 7(4):505-16
Chapter 5: Emerging drugs for coronary artery disease. From past achievements and 89
current needs to clinical promises.
Expert Opinion on Emerging Drugs. 2011 Jun; 16(2):203-233.
Chapter 6: Restenosis after PCI- Part II: Prevention and therapy. 145
Nature Reviews Cardiology 2011 Oct 11[Epub ahead of print]
Chapter 7: Late stent malapposition in the bare metal stent and drug eluting stent era. 173
Book Chapter In: Coronary Stent Restenosis (eds. Tintoiu IC, Popma JJ, Bae J-H, Rivard A,
Galassi AR, Gabrie C. – Bucharest: The Publishing House of the Romanian Academy, 2011,
ISBN 978-973-27-2034-9. Chapter 16)
Chapter 8: Summary, conclusions and future perspectives. 187
Chapter 9: Samenvatting, conclusies en toekomstperspectief. 195
Acknowledgement 205
Curriculum Vitae 209
List of Publications 215
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Ch apter 1
General introduction
and outline of the thesis
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