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Third Edition
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This Study Guide was written by Brian Kipp, PhD, APPLYING YOUR KNOWLEDGE
to accompany the third edition of Essentials of
Pathophysiology: Concepts of Altered Health Statesby
The second section of each Study Guide chapter
Carol Mattson Porth. The Study Guide is designed
consists of case study-based exercises that ask you
to help you practice and retain the knowledge
to begin to apply the knowledge you’ve gained
you’ve gained from the textbook, and give you a
from the textbook chapter and reinforced in the
basis for applying it in your practice. The following
first section of the Study Guide chapter. A case
types of exercises are provided in each chapter of
study scenario based on the chapter’s content is
the Study Guide.
presented, and then you are asked to answer some
questions, in writing, related to the case study. The
questions could cover lab values, next steps in
ASSESSING YOUR treatment, anticipated diagnoses, and the like.
UNDERSTANDING
PRACTICING FOR NCLEX
The first section of each Study Guide chapter
concentrates on the basic information of the
textbook chapter and helps you to remember key The third and final section of the Study Guide
concepts, vocabulary, and principles. helps you practice NCLEX-style questions while
further reinforcing the knowledge you have been
■ Fill in the Blanks: Fill-in-the-blank exercises
gaining and testing for yourself through the
test important chapter information, encourag-
textbook chapter and the first two sections of the
ing you to recall key points.
study guide chapter. In keeping with the NCLEX,
■ Labeling: Labeling exercises are used where the questions presented are multiple-choice and
you need to remember certain visual represen- scenario-based, asking you to reflect, consider,
tations of the concepts presented in the and apply what you know and to choose the best
textbook. answer out of those offered.
■ Matching: Matching questions test you
knowledge of the definition of key terms.
ANSWER KEYS
■ Sequencing: Sequencing exercises ask you to
remember particular sequences or orders, for
The answers for all of the exercises and questions
instance of normal or abnormal physiologic
in the Study Guide are provided at the back of
processes.
the book, so you can assess your own learning as
■ Short Answers: Short-answer questions cover you complete each chapter.
facts, concepts, procedures, and principles of We hope you will find this Study Guide to be
the chapter. These questions ask you to recall helpful and enjoyable, and we wish you every
information as well as demonstrate your success in your studies and future profession.
comprehension of the information.
The Publishers
iii
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CCoonntteennttss
1 CHAPTER 9
UNIT
Stress and Adaptation 49
CELL AND TISSUE FUNCTION 1
CHAPTER 10
CHAPTER 1
Disorders of Nutritional Status 53
Cell Structure and Function 1
3
CHAPTER 2 UNIT
Cellular Responses to Stress, Injury, HEMATOPOIETIC FUNCTION 57
and Aging 6
CHAPTER 11
CHAPTER 3
Disorders of White Blood Cells and
Inflammation, the Inflammatory Response, Lymphoid Tissues 57
and Fever 12
CHAPTER 12
CHAPTER 4
Disorders of Hemostasis 62
Cell Proliferation and Tissue Regeneration
and Repair 17
CHAPTER 13
Disorders of Red Blood Cells 67
CHAPTER 5
Genetic Control of Cell Function
and Inheritance 20 UNIT 4
INFECTION AND IMMUNITY 73
CHAPTER 6
Genetic and Congenital Disorders 26
CHAPTER 14
CHAPTER 7 Mechanisms of Infectious Disease 73
Neoplasia 32
CHAPTER 15
Innate and Adaptive Immunity 78
2
UNIT
INTEGRATIVE BODY FUNCTIONS 39 CHAPTER 16
Disorders of the Immune Response 84
CHAPTER 8
Disorders of Fluid, Electrolyte,
and Acid-Base Balance 39
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vi CONTENTS
5 CHAPTER 27
UNIT
Disorders of the Bladder and
CIRCULATORY FUNCTION 90
Lower Urinary Tract 152
CHAPTER 17
8
UNIT
Control of Cardiovascular Function 90
GASTROINTESTINAL AND HEPATOBILIARY
CHAPTER 18 FUNCTION 157
Disorders of Blood Flow and
Blood Pressure 96 CHAPTER 28
Structure and Function
CHAPTER 19 of the Gastrointestinal System 157
Disorders of Cardiac Function 104
CHAPTER 29
CHAPTER 20 Disorders of Gastrointestinal
Function 162
Heart Failure and Circulatory Shock 112
CHAPTER 30
6 Disorders of Hepatobiliary and
UNIT
Exocrine Pancreas Function 169
RESPIRATORY FUNCTION 118
9
UNIT
CHAPTER 21
Control of Respiratory System 118 ENDOCRINE SYSTEM 176
CHAPTER 22 CHAPTER 31
Respiratory Tract Infections, Neoplasms, Mechanisms of Endocrine Control 176
and Childhood Disorders 124
CHAPTER 32
CHAPTER 23 Disorders of Endocrine Control
Disorders of Ventilation of Growth and Metabolism 180
and Gas Exchange 130
CHAPTER 33
Diabetes Mellitus and the Metabolic
7 Syndrome 187
UNIT
KIDNEY AND URINARY TRACT FUNCTION 137
10
UNIT
CHAPTER 24
NERVOUS SYSTEM 194
Structure and Function of the Kidney 137
CHAPTER 34
CHAPTER 25
Organization and Control of Neural
Disorders of Renal Function 142 Function 194
CHAPTER 26 CHAPTER 35
Acute Renal Failure and Chronic Somatosensory Function, Pain, and
Kidney Disease 148 Headache 201
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CONTENTS vii
CHAPTER 36 12
UNIT
Disorders of Neuromuscular Function 210
MUSCULOSKELETAL FUNCTION 253
CHAPTER 37
CHAPTER 42
Disorders of Brain Function 218
Structure and Function of the
Skeletal System 253
CHAPTER 38
Disorders of Special Sensory Function:
CHAPTER 43
Vision, Hearing, and Vestibular
Disorders of the Skeletal System:
Function 226
Trauma, Infections, Neoplasms, and
Childhood Disorders 258
11
UNIT
CHAPTER 44
GENITOURINARY AND
REPRODUCTIVE FUNCTION 237 Disorders of the Skeletal System:
Metabolic and Rheumatic Disorders 264
CHAPTER 39
Disorders of the Male UNIT 13
Genitourinary System 237
INTEGUMENTARY FUNCTION 269
CHAPTER 40
CHAPTER 45
Disorders of the Female
Structure and Function of the Skin 269
Genitourinary System 242
CHAPTER 46
CHAPTER 41
Disorders of Skin Integrity and Function 273
Sexually Transmitted Infections 249
Answer Key 280
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Description:This Study Guide is designed to accompany Essentials of Pathophysiology, Third Edition. The study guide follows the outline of the text, containing 45 chapters. Each chapter offers learning objectives that match the text; Assessing Your Understanding activities including fill-in-the-blanks, labeling