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G Y N E C O L O G Y
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STEP-UP
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gynecology
Frank W. Ling, MD Sandra Ann Carson, MD
Clinical Professor Adjunct Professor of Obstetrics and Gynecology
Department of Obstetrics and Gynecology Alpert Medical School of Brown University
Vanderbilt University School of Medicine and Meharry Providence, Rhode Island
Medical College Director, American Board of Obstetrics and Gynecology
Nashville, Tennessee Dallas, Texas
Partner, Women’s Health Specialists
Germantown, Tennessee Wesley C. Fowler, Jr., MD
Director, The Foundation for Exxcellence in Women's
Associate Dean for Medical Alumni Affairs
Health Care
Professor of Obstetrics And Gynecology
Dallas, Texas
University of North Carolina School of Medicine
Russell R. Snyder, MD Chapel Hill, North Carolina
President, The Foundation for Exxcellence in Women's
Vice-Chair and Director, Division of Gynecology Health Care
Department of Obstetrics and Gynecology Dallas, Texas
University of Texas Medical Branch
Galveston, Texas
Director, The Foundation for Exxcellence in Women's
Health Care
Dallas, Texas
^■j Woiters Kluwer
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1st Edition
Copyright © 2015 Wolters Kluwer Health | Lippincott Williams & Wilkins.
All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted
in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by
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Library of Congress Cataloging-in-Publication Data
Step-up to obstetrics and gynecology / [edited by] Frank W. Ling, Russell R. Snyder, Sandra Ann Carson,
Wesley C. Fowler. — 1st edition,
p.; cm. — (Step-up series)
Includes bibliographical references and index.
ISBN 978-1-4511-1244-3 (alk. paper)
I. Ling, Frank W., editor. II. Snyder, Russell R. editor. III. Carson, Sandra A. (Sandra Ann), editor. IV. Fowler,
Wesley C., Jr., 1940- editor. V. Series: Step up series.
[DNLM: 1. Pregnancy Complications—Examination Questions. 2. Pregnancy Complications—Outlines. 3.
Genital Diseases, Female—Examination Questions. 4. Genital Diseases, Female—Outlines. WQ 18.2]
RG111
618.076—dc23
2014008800
Care has been taken to confirm the accuracy of the information presented and to describe generally accepted
practices. However, the author(s), editors, and publisher are not responsible for errors or omissions or for any
consequences from application of the information in this book and make no warranty, expressed or implied,
with respect to the currency, completeness, or accuracy of the contents of the publication. Application of this
information in a particular situation remains the professional responsibility of the practitioner; the clinical treat
ments described and recommended may not be considered absolute and universal recommendations.
The author(s), editors, and publisher have exerted every effort to ensure that drug selection and dosage set
forth in this text are in accordance with the current recommendations and practice at the time of publication.
However, in view of ongoing research, changes in government regulations, and the constant flow of information
relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for
any change in indications and dosage and for added warnings and precautions. This is particularly important
when the recommended agent is a new or infrequently employed drug.
Some drugs and medical devices presented in this publication have Food and Drug Administration (FDA)
clearance for limited use in restricted research settings. It is the responsibility of the health care provider to
ascertain the FDA status of each drug or device planned for use in his or her clinical practice.
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Section Editors
FRANK W. LING, MD SANDRA ANN CARSON, MD
Section 2: Obstetrics Section 4: Reproductive Endocrinology and Infertility
Clinical Professor Adjunct Professor of Obstetrics and Gynecology
Department of Obstetrics and Gynecology Alpert Medical School of Brown University
Vanderbilt University School of Medicine and Providence, Rhode Island
Meharry Medical College Director, American Board of Obstetrics and
Nashville, Tennessee Gynecology
Partner, Women's Health Specialists, PLLC Dallas, Texas
Germantown, Tennessee
Director, The Foundation for Exxcellence in Women's WESLEY C. FOWLER, JR., MD
Health Care Section 5: Gynecologic Oncology
Dallas, Texas Associate Dean for Medical Alumni Affairs
Professor of Obstetrics And Gynecology
RUSSELL R. SNYDER, MD University of North Carolina School of Medicine
Section 1: Overview of Women's Health Chapel Hill, North Carolina
Section 3: Gynecology President, The Foundation for Exxcellence in
Vice-Chair and Director, Division of Gynecology Women's Health Care
Department of Obstetrics and Gynecology Dallas, Texas
University of Texas Medical Branch
Galveston, Texas
Director, The Foundation for Exxcellence in Women's
Health Care
Dallas, Texas
v
Contributing Authors
✓
MICHAEL T. ADLER, MD BETTY CHOU, MD
Chapter 25: Postterm Pregnancy and Intrauterine Fetal Chapter 16: Common Medical and Surgical Problems in
Demise Pregnancy
Chapter 26: Obstetric Procedures Chapter 20: Fetal Growth Abnormalities: Fetal Growth
Assistant Professor of Obstetrics and Gynecology Restriction and Macrosomia
Department of Obstetrics and Gynecology Director, Johns Hopkins Women's Services at
University of Texas Medical School at Houston Odenton
Houston, Texas Assistant Professor
Department of Obstetrics and Gynecology
PAMELA D. BERENS, MD Johns Hopkins Bayview Medical Center
Chapter 2: The Obstetrician/Gynecologist's Role in Baltimore, Maryland
Screening and Preventive Care
Chapter 14: Postpartum Care/Complications ALICE CHUANG, MD
Professor, Vice Chair of Clinical Affairs Chapter 45: Cell Biology and Principles of Cancer
Department of Obstetrics and Gynecology Therapy
University of Texas Medical School at Houston Chapter 46: Gestational Trophoblastic Neoplasia
Houston, Texas Chapter 50: Ovarian and Adnexal Disease
Associate Professor
MOSTAFA A. BORAHAY, MD, FACOG Department of Obstetrics and Gynecology
Chapter 34: Dysmenorrhea and Chronic Pelvic Pain University of North Carolina
Assistant Professor Chapel Hill, North Carolina
Women's Reproductive Health Research (WRHR)
Scholar LESLIE CLARK, MD
Department of Obstetrics and Gynecology Chapter 45: Cell Biology and Principles of Cancer
University of Texas Medical Branch Therapy
Galveston, Texas Resident
Department of Obstetrics and Gynecology
University of North Carolina
AMY M. BURKETT, MD
Chapel Hill, North Carolina
Chapter 18: Hypertension in Pregnancy
Department of Obstetrics and Gynecology
BRENDAN D. CONNEALY, MD
Summa Health Systems
Chapter 6: Endocrinology of Pregnancy
Northeastern Ohio Universities College of
Chapter 12: Immediate Care of Newborn
Medicine
MFM Fellow
Akron, Ohio
Department of Obstetrics and Gynecology
University of Texas Medical School at Houston
CHRISTINNE CANELA, MD
Houston, Texas
Chapter 41: Hirsutism and Virilization
Physician Director of Medical Quality DOUGLAS R. DANFORTH, PHD
Department of Obstetrics and Gynecology Chapter 5: Reproductive Physiology
Carilion Roanoke Memorial Hospital Associate Professor
Roanoke, Virginia Department of Obstetrics and Gynecology
The Ohio State University Medical Center
Columbus, Ohio
CONTRIBUTING AUTHORS • VÍ¡
JILL EDWARDSON, MD, MPH JAOU-CHEN HUANG, MD
Chapter 16: Common Medical and Surgical Problems in Chapter 43: Infertility
Pregnancy Reproductive Endocrinologist
Assistant Professor Department of Obstetrics and Gynecology
Department of Obstetrics and Gynecology Memorial Hermann Hospital
Johns Hopkins Medical Center Houston, Texas
Baltimore, Maryland
NANCY A. HUEPPCHEN, MD
CYNTHIA B. EVANS, MD Chapter 16: Common Medical and Surgical Problems
Chapter 42: Menopause in Pregnancy
Associate Professor Chapter 20: Fetal Growth Abnormalities: Fetal Growth
Department of Obstetrics and Gynecology Restriction and Macrosomia
The Ohio State University Medical Center Director of Medical Education
Columbus, Ohio Associate Professor
Department of Obstetrics and Gynecology
JASON FRANASIAK, MD Johns Hopkins University School of Medicine
Chapter 49: Cancer of the Uterine Corpus Baltimore, Maryland
Physician at Reproductive Medicine Associates of
New Jersey PATRICIA HUGUELET, MD, FACOG
Obstetrics and Gynecology Chapter 17: Infectious Diseases in Pregnancy
Gladstone, New Jersey Assistant Professor
Department of Obstetrics and Gynecology
MELISSA M. GOIST, MD University of Colorado, Anschutz Medical Center
Chapter 15: Ectopic Pregnancy Aurora, Colorado
Assistant Professor
Department of Obstetrics and Gynecology ANDREW F. HUNDLEY, MD
The Ohio State University Medical Center Chapter 32: Pelvic Support Defects, Urinary
Columbus, Ohio Incontinence, and Urinary Tract Infection
Division Director, Female Pelvic Medicine and
SUSAN GOLDSMITH, MD Reconstructive Surgery
Chapter 8: Preconception and Antepartum Care Department of Obstetrics and Gynecology
Assistant Professor The Ohio State University Medical Center
Department of Obstetrics and Gynecology Columbus, Ohio
Northwestern University Feinberg School of Medicine
Chicago, Illinois MICHELLE M. ISLEY, MD, MPH
Chapter 28: Sterilization
MATTHEW GRACE, MD Assistant Professor
Chapter 47: Benign Vulvar Disease Department of Obstetrics and Gynecology
Assistant Professor The Ohio State University Medical Center
Department of Obstetrics and Gynecology Columbus, Ohio
University of North Carolina
Chapel Hill, North Carolina CHERYL J. JOHNSON, MD
Chapter 1: The Woman's Health Examination
CATHERINE HANSEN, MD, MPH Department of Obstetrics and Gynecology
Chapter 37: Sexual Function and Dysfunction Summa Health System
Assistant Professor Ohio State University
Department of Obstetrics and Gynecology Akron, Ohio
University of Texas Medical Branch
Galveston, Texas BENJAMIN A. KASE, MD
Chapter 7: Maternal-Fetal Physiology
GERI D. HEWITT, MD Department of Obstetrics and Gynecology
Chapter 39: Puberty Tripler Army Medical Center
Assistant Professor Honolulu, Hawaii
Department of Obstetrics and Gynecology
The Ohio State University Medical Center
Columbus, Ohio
viii • CONTRIBUTING AUTHORS
AMANTIA KENNEDY, MD SILKA PATEL, MD
Chapter 46: Gestational Trophoblastic Neoplasia Chapter 13: Abnormal Labor and Malpresentation
Assistant Professor Assistant Professor
Department of Obstetrics and Gynecology Department of Obstetrics and Gynecology
University of North Carolina Johns Hopkins School of Medicine
Chapel Hill, North Carolina Baltimore, Maryland
SAMI GOKHAN KILIC, MD, FACOG, FACS PAMELA A. PROMECENE, MD
Chapter 36: Gynecologic Procedures Chapter 3: Ethics in Obstetrics and Gynecology
Assistant Professor Chapter 10: Normal Labor and Delivery
Department of Obstetrics and Gynecology Associate Professor of Obstetrics and Gynecology-
University of Texas Medical Branch Clinical
Galveston, Texas Assistant Dean for Graduate Medical Education
Department of Obstetrics and Gynecology
EDUARDO LARA-TORRE, MD University of Texas Medical School at Houston
Chapter 41: Hirsutism and Virilization Houston, Texas
Chapter 44: Premenstrual Syndrome and Premenstrual
Dysphoric Disorder TRACY L. PROSEN, MD
Residency Program Director Chapter 19: Multifetal Gestation
Department of Obstetrics and Gynecology Assistant Professor
Carilion Roanoke Memorial Hospital Department of Obstetrics, Gynecology and Women's
Roanoke, Virginia Health
University of Minnesota
FRANK W. LING, MD Minneapolis, Minnesota
Chapter 35: Breast Disorders
Clinical Professor KELLIE S. RATH, MD
Department of Obstetrics and Gynecology Chapter 4: Embryology and Anatomy
Vanderbilt University School of Medicine and OhioHealth Gynecologic Cancer Surgeons
Meharry Medical College Columbus, Ohio
Nashville, Tennessee
Partner, Women's Health Specialists BRITTON D. RINK, MD
Germantown, Tennessee Chapter 9: Prenatal Diagnosis, Genetic Disorder
Director, The Foundation for Exxcellence in Women's Assessment, and Teratology
Health Care Director, Prenatal Genetics and Ultrasound
Dallas, Texas Assistant Professor
Department of Obstetrics and Gynecology
QUINN LIPPMANN, MD, MPH The Ohio State University Medical Center
Chapter 48: Cervical Dysplasia and Carcinoma Columbus, Ohio
Oth Post-MD
Department of Reproductive Medicine ANA M. RODRIGUEZ, MD
University of California San Diego Chapter 27: Contraception
San Diego, California Assistant Professor
Department of Obstetrics and Gynecology
AMANDA B. MURCHISON, MD University of Texas Medical Branch
Chapter 22: Preterm Labor Galveston, Texas
Chapter 23: Third-Trimester Bleeding
Assistant Residency Program Director JACQUELINE ROHL, MD, MPH
Department of Obstetrics and Gynecology Chapter 29: Reproductive Tract Congenital
Carilion Roanoke Memorial Hospital Anomalies
Roanoke, Virginia Assistant Professor
Department of Obstetrics and Gynecology
JESSICA L. NYHOLM, MD The Ohio State University Medical Center
Chapter 11: Intrapartum Fetal Surveillance Columbus, Ohio
Assistant Professor
Department of Obstetrics, Gynecology and Women's
Health
University of Minnesota
Minneapolis, Minnesota
