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About Spina Bifida
This document is a systematic review of risk factors associated with the onset and progression of spina bifida. The review included 3 meta-analyses and 63 observational studies on risk factors for disease onset. The meta-analyses found that maternal obesity prior to pregnancy and paternal exposure to Agent Orange significantly increase the risk of spina bifida in offspring. One observational study examined risk factors for disease progression. While many potential risk factors have been studied, strong evidence currently only exists for the association between maternal obesity, paternal Agent Orange exposure, and spina bifida onset. The review aims to inform policymakers on modifiable risk factors to reduce the burden of this birth defect.
Detailed Information
| Author: | ['Constanzza Arellano Leiva'] |
|---|---|
| Publication Year: | 2019 |
| Pages: | 35 |
| Language: | English |
| Format: | |
| Price: | FREE |
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