Shifting ParadigmS in Live Kidney donation and tranSPLantation

236 Pages·2015·12.36 MB·English

Shifting ParadigmS in Live Kidney donation and tranSPLantation
Jef Lafranca
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The studies described in this thesis were performed at the Department of Surgery, Erasmus MC,
University Medical Center Rotterdam, Rotterdam, The Netherlands.
Printing of this thesis has been fnancially supported by:
Applied Medical
Astellas Pharma
Chiesi
Chipsoft
Covidien
Erasmus MC – Afdeling Heelkunde
Nederlandse Transplantatie Vereniging
Nierstichting
Olympus
ISBN:
Cover design by James Jardine
Layout and printing: Ridderprint, Ridderkerk, The Netherlands
Copyright J.A. Lafranca, Rotterdam, The Netherlands. No parts of this thesis may be reproduced, stored in
a retrieval system, or transmitted in any form or by any means without permission of the corresponding
journals or the author.
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SHIFTING PARADIGMS IN LIVE KIDNEY DONATION AND TRANSPLANTATION
Verschuivende gedachtepatronen betrefende nierdonatie bij leven en niertransplantatie
Proefschrift
ter verkrijging van de graad van doctor aan de
erasmus Universiteit rotterdam
op gezag van de
rector magnifcus
Prof.dr. H.A.P. Pols
en volgens besluit van het College voor Promoties.
de openbare verdediging zal plaatsvinden op
dinsdag 23 juni 2015 om 13.30 uur
door
Jefrey Anthony Lafranca
geboren te Rotterdam
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PromotieCommiSSie
Promotor Prof.dr. J.N.M. IJzermans
Overige leden Prof.dr. H.W. Tilanus
Prof.dr. W. Weimar
Prof.dr. T. van Gelder
Copromotor Dr. F.J.M.F. Dor
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Voor mijn ouders
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tabLe of ContentS
Chapter 1: General introduction, aim and outline of the thesis 9
Part 1 – extended Criteria Live Kidney donors: review & attitudes
Chapter 2: Shifting paradigms in eligibility criteria for live kidney donation: a systematic review 19
Kidney International 2015 (PMID: 24786706)
Chapter 3: Attitudes among transplant professionals towards shifting paradigms in live kidney 49
donation
Submitted
Chapter 4: The need for a standardized informed consent procedure in live donor nephrec- 69
tomy: a systematic review
Transplantation 2014 (PMID: 25436923)
Part 2 – obesity in live kidney donation
Chapter 5: Systematic review and meta-analysis of the relation between body mass index and 89
short-term donor outcome of laparoscopic donor nephrectomy
Kidney International 2013 (PMID: 23344469)
Chapter 6: Perirenal and intra-abdominal fat mass superior over body mass index in predicting 107
donor outcome in laparoscopic donor nephrectomy
Submitted
Part 3 – obesity in renal transplant recipients
Chapter 7: Body Mass Index and outcome in renal transplant recipients: a systematic review 119
and meta-analysis
Accepted for publication: BMC Medicine
Part 4 – other extended criteria in live kidney donation
Chapter 8: Complex vascular anatomy should not be a contra-indication for live kidney dona- 153
tion and transplantation
Submitted
Chapter 9: Donors with stone-bearing kidneys are eligible for living kidney donation: a system- 169
atic review and cohort analysis
Submitted
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Part 5 – Summary, general discussion & appendices
Chapter 10: Summary / samenvatting 197
Engels 198
Nederlands 202
Chapter 11: General discussion and future perspectives 207
Chapter 12: Appendices 217
Contributing authors 219
Acknowledgements / dankwoord 223
List of publications 227
Ph.D. Portfolio 231
Curriculum Vitae 235
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Chapter 1 1
2
General introduction,
aim and outline of the thesis 3
JA Lafranca1
5
1. Department of Surgery, Erasmus MC, University Medical Center Rotterdam,
The Netherlands 6
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