Table Of Contenti
Schizophrenia and
Related Disorders
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Schizophrenia
and Related
Disorders
Edited by
Michael J. Marcsisin, MD
Assistant Professor
Department of Psychiatry
University of Pittsburgh School of Medicine
Jessica M. Gannon, MD
Assistant Professor
Department of Psychiatry
University of Pittsburgh School of Medicine
Jason B. Rosenstock, MD
Associate Professor
Department of Psychiatry
University of Pittsburgh School of Medicine
Director, Medical Student Education
Western Psychiatric Institute and Clinic
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1
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Published in the United States of America by Oxford University Press
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© Oxford University Press 2017
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You must not circulate this work in any other form
and you must impose this same condition on any acquirer.
Library of Congress Cataloging-in-Publication Data
Names: Marcsisin, Michael J., editor. | Gannon, Jessica M., editor. |
Rosenstock, Jason, editor.
Title: Schizophrenia and related disorders / edited by Michael J. Marcsisin,
Jessica M. Gannon, Jason B. Rosenstock.
Other titles: Pittsburgh pocket psychiatry series.
Description: Oxford ; New York : Oxford University Press, [2016] | Series:
Pittsburgh pocket psychiatry series | Includes bibliographical references.
Identifiers: LCCN 2016009493 (print) | LCCN 2016010135 (ebook) |
ISBN 9780199331505 (pbk. : alk. paper) | ISBN 9780199331512 (U-pdf) |
ISBN 9780199331529 (Epub)
Subjects: | MESH: Schizophrenia
Classification: LCC RC514 (print) | LCC RC514 (ebook) | NLM WM 203 |
DDC 616.89/8—dc23
LC record available at http://lccn.loc.gov/2016009493
This material is not intended to be, and should not be considered, a substitute for medical
or other professional advice. Treatment for the conditions described in this material is highly
dependent on the individual circumstances. And, while this material is designed to offer
accurate information with respect to the subject matter covered and to be current as of the
time it was written, research and knowledge about medical and health issues is constantly
evolving and dose schedules for medications are being revised continually, with new side
effects recognized and accounted for regularly. Readers must therefore always check the
product information and clinical procedures with the most up-to-date published product
information and data sheets provided by the manufacturers and the most recent codes
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in the material. The authors and the publisher do not accept, and expressly disclaim, any
responsibility for any liability, loss or risk that may be claimed or incurred as a consequence
of the use and/or application of any of the contents of this material.
9 8 7 6 5 4 3 2 1
Printed by Sheridan Books, Inc., United States of America
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Series Introduction
We stand on the threshold of a new golden age of clinical and
behavioral neuroscience with psychiatry at its fore. With the
Pittsburgh Pocket Psychiatry series, we intend to encompass
the breadth and depth of our current understanding of human
behavior in health and disease. Using the structure of resident
didactic teaching, we will be able to ensure that each subject
area relevant to practicing psychiatrists is detailed and described.
New innovations in diagnosis and treatment will be reviewed and
discussed in the context of existing knowledge, and each book
in the series will propose new directions for scientific inquiry
and discovery. The aim of the series as a whole is to integrate
findings from all areas of medicine and neuroscience previously
segregated as “mind” or “body,” “psychological” or “biological.”
Thus, each book from the Pittsburgh Pocket Psychiatry series will
stand alone as a standard text for anyone wishing to learn about
a specific subject area. The series will be the most coherent and
flexible learning resource available.
David Kupfer, MD
Michael Travis, MD
Michelle Horner, DO
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Contents
Contributors ix
1 History and Phenomenology of Schizophrenia
and Related Psychoses 1
Michael J. Marcsisin and Jessica M. Gannon
2 Diagnosis and Assessment of Schizophrenia
and Related Psychoses 53
Jason B. Rosenstock
3 Epidemiology of Schizophrenia 89
Jaspreet S. Brar
4 Course, Prognosis, and Outcomes
of Schizophrenia and Related Disorders 111
Konasale M. Prasad
5 Neurobiology of Schizophrenia 143
Gil D. Hoftman and Dean F. Salisbury
6 Somatic Treatments for Psychotic Disorders 185
Justin C. Ellison, Jason B. Rosenstock,
and Michael J. Marcsisin
7 Psychosocial Treatment for Psychotic
Disorders 247
Jessica M. Gannon and Shaun M. Eack
Answers 293
Index 295
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Contributors
Jaspreet S. Brar, Michael J. Marcsisin, MD
MD, PhD Department of Psychiatry
Department of Psychiatry University of Pittsburgh School
University of Pittsburgh of Medicine
School of Medicine Western Psychiatric Institute
Western Psychiatric Institute and Clinic
and Clinic Pittsburgh, Pennsylvania
Pittsburgh, Pennsylvania
Konasale M. Prasad, MD
Shaun M. Eack, PhD Department of Psychiatry
University of Pittsburgh University of Pittsburgh School
School of Social Work of Medicine
Pittsburgh, Pennsylvania Western Psychiatric Institute
Justin C. Ellison, and Clinic
PharmD, BCPP Pittsburgh, Pennsylvania
Department of Pharmacy Jason B. Rosenstock, MD
University of Pittsburgh Department of Psychiatry
School of Pharmacy University of Pittsburgh School
Western Psychiatric Institute of Medicine
and Clinic Western Psychiatric Institute
Pittsburgh, Pennsylvania and Clinic
Jessica M. Gannon, MD Pittsburgh, Pennsylvania
Department of Psychiatry Dean F. Salisbury, PhD
University of Pittsburgh Department of Psychiatry
School of Medicine University of Pittsburgh School
Western Psychiatric Institute of Medicine
and Clinic Western Psychiatric Institute
Pittsburgh, Pennsylvania and Clinic
Gil D. Hoftman, Pittsburgh, Pennsylvania
MD, PhD
Department of Psychiatry
University of Pittsburgh School
of Medicine
Western Psychiatric Institute
and Clinic
Pittsburgh, Pennsylvania
