RSSDI Textbook of Diabetes Mellitus

1492 Pages·2014·93.281 MB·English

by  Hemraj B Chandalia

RSSDI
TEXTBOOK OF
DIABETES MELLITUS

RSSDI
TEXTBOOK OF
DIABETES MELLITUS
Third Edition
Editor-in-Chief
Hemraj B Chandalia
Executive Editor
Gumpeny Ramachandra Sridhar
Editors
Ashok Kumar Das
Sri Venkata Madhu
Viswanathan Mohan
Paturi Vishnupriya Rao
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© 2014, Research Society for the Study of Diabetes in India
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of editor(s) of the book.
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matter in question. However, readers are advised to check the most current information available on procedures included and check information
from the manufacturer of each product to be administered, to verify the recommended dose, formula, method and duration of administration,
adverse effects and contraindications. It is the responsibility of the practitioner to take all appropriate safety precautions. Neither the publisher
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RSSDI Textbook of Diabetes Mellitus
Second Edition: 2008
Revised and Reprint: 2012
Third Edition: 2014
ISBN: 978-93-5152-090-0
Printed at:
DEDICATION
RSSDI Textbook of Diabetes Mellitus
Third Edition
(1929 to 1998)
Prof MMS Ahuja was one of the major driving forces behind this textbook. It is unfortunate
that he passed away on July 12, 1998, when the first edition of this textbook was in its initial
stages of preparation. It took us a great deal of time to pick the threads of editorial process where
Prof Ahuja had left them and ultimately put the first edition together. Prof Ahuja was Head of
the Departments of Medicine and Endocrinology at the prestigious All India Institute of Medical
Sciences for several decades. He combined the qualities of a compassionate physician, an
inspiring teacher and an inquisitive researcher—a combination difficult to find in modern times.
He was a prolific writer and edited a highly popular series of review books entitled “Progress in
Medicine”. In the areas of diabetology, his research work covered epidemiology, ketosis resistant
diabetes in young, cardiovascular complications, nutrition and patient education. He has left his
distinctive stamp in these fields. Prof Ahuja was one of the founders of Research Society for the
Study of Diabetes in India and the major working force behind this society’s progress. He founded
and edited the ‘International Journal of Diabetes in Developing Countries’ from 1980 onwards,
until the time of his collaboration in 1991 with other editors. This textbook continues to bear
the stamp of his excellence. We, the editors of this textbook owe a great deal of gratitude to our
pioneering colleague, Prof Ahuja and pay him a respectful tribute.

DEDICATION
RSSDI Textbook of Diabetes Mellitus
Third Edition
(1923 to 2010)
Prof BB Tripathy was a doyen among physicians and diabetologists. He was an outstanding
researcher and an astute clinician who produced some of the best epidemiological research at
a time when the field of epidemiology was in its nascent stage in India. His work was highly
signi ficant in describing the clinical features of an atypical form of ketosis-resistant diabetes
which was associated with malnutrition. Prof Tripathy organized a landmark international
workshop “Diabetes peculiar to the Tropics” in 1995 at Cuttack. His knowledge was extensive
and encompassed the fields of medicine, biochemistry, pharmaco logy, nutrition and epidemiology.
He was Editor-in-Chief of RSSDI Textbook of Diabetes, First and Second editions. He was the
Founder Vice President of the Research Society for Study of Diabetes in India (RSSDI) and was
connected with this organization till his demise as an Executive Patron. RSSDI is heavily indebted
to Prof Tripathy for his contributions and inspiring leadership.

Editors
Prof (Dr) Hemraj B Chandalia MD FACP
• Director, Endocrinology, Diabetes and Metabolism, Jaslok Hospital
and Research Centre, Mumbai
• Director, Dr Chandalia’s Diabetes Endocrine Nutrition Management
and Research Centre, Mumbai
• Honorary Professor of Medicine and Diabetes, Grant Medical College
and Sir JJ Group of Hospitals, Mumbai (1971–2000)
• Patron and Past President, Research Society for the Study of Diabetes
in India
• Founding Editor, International Journal of Diabetes in Developing
Countries
• Research Interests: Glycated Hemoglobin, Lactic Acidosis, Nutrition in
Diabetes, Patient-Education, Prevention of Type 2 Diabetes.
• RSSDI Textbook—First, Second and Second Revised Edition: Executive
Editor
• RSSDI Textbook—Third Edition: Editor-in-Chief
• Chapters authored: 16, 43, 48, 53, 88, 92, 94; Section Editor: Sections
1, 2, 3, 4, 5, 9
Prof (Dr) Gumpeny Ramachandra Sridhar MD DM FACE
FRCP (Glasgow)
• Director, Endocrine and Diabetes Centre, Vishakhapatnam
• Adjunct Professor, Bioinformatics, Andhra University, College of
Engineering
• President, Research Society for the Study of Diabetes in India (2010)
• President, Endocrine Society of India (2013–2014)
• Founding Editor, Indian Journal of Endocrinology and Metabolism
(1997–2000)
• Editor-in-Chief, International Journal of Diabetes in Developing
Countries (2013 onwards)
• Research Interests: Clinical Informatics, Computational Biology and
Bioinformatics, Psychological Aspect of Diabetes
• RSSDI Textbook—Third Edition: Executive Editor
• Chapters authored: 33, 71, 81, 82, 85; Section Editor: Sections 10, 11,
12, 13, 14, 15