Recent Developments in Alcoholism: Volume 12: Alcoholism and Women (Recent Developments in Alcoholism)

473 Pages·1995·3.12 MB·English

by  Marc Galanter

RECENTDEVELOPMENTS IN
ALCOHOLISM
VOLUME12
ALCOHOLISMAND WOMEN
RECENT
DEVELOPMENTS IN
Editedby
MARC GALANTER
New York University School of Medicine
New York, New York
Associate Editors
HENRI BEGLEITER, RICHARD DEITRICH,
DONALD GALLANT, DONALD GOODWIN,
EDWARD GOTTHEIL, ALFONSO PAREDES,
MARCUS ROTHSCHILD, and DAVID VAN THIEL
Assistant Editor
HELENEDWARDS
AnOfficial Publication ofthe American SocietyofAddictionMedicine
andtheResearchSocietyonAlcoholism.
Thisseries was founded bytheNational Council onAlcoholism.
ALCOHOLISM
VOLUME 12
ALCOHOLISM AND WOMEN
KLUWER ACADEMIC PUBLISHERS
NEW YORK / BOSTON / DORDRECHT / LONDON / MOSCOW
eBookISBN: 0-306-47138-8
Print ISBN: 0-306-44921-8
©2002 Kluwer Academic Publishers
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Print ©1995 KluwerAcademic / Plenum Publishers
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EditorialBoard
Chair: ChairEmeritusandFounder:
JamesD.Beard,Ph.D. CharlesS.Lieber,M.D.
Ronald L.Alkana,Ph.D. JudithS.Gavaler,Ph.D. MackC.Mitchell,M.D.
IrinaAnokhina,Ph.D. H.WernerGoedde, M.D. YasuhikoMizoi,M.D.
MarleneO.Berman,Ph.D. AdrienneS.Gordon,Ph.D. RogerNordmann, M.D.,Ph.D.
StefanBorg,M.D. KathleenA.Grant,Ph.D. BarryJ.Potter,Ph.D.
AllanC.Collins,Ph.D. ConsueloGuerri,Ph.D. MarciaRussell,Ph.D.
DavidW.Crabb,M.D. AnastacioM.Hoyumpa,M.D. MikkoSalaspuro,M.D.
JohnCrabbe,Ph.D. HiromasaIshii,M.D. StevenSchenker,M.D.
CarolC.Cunningham,Ph.D. ThomasR.Jerrells,Ph.D. MichaelF.Sorrell,M.D.
PhilipeA.J.DeWitte,Ph.D. Harold Kalant,M.D., Ph.D. JalieA.Tucker,Ph.D.
MichaelJ.Eckardt, Ph.D. Ting-KaiLi,M.D. DeanJ.Tuma,Ph.D.
DanielFlavin,M.D. JohnM.Littleton,Ph.D. JoanneWeinberg,Ph.D.
Richard Fuller,M.D. BarbaraS.McCrady,Ph.D. JamesR.West,Ph.D.
ResearchSocietyonAlcoholism AmericanSocietyof
AddictionMedicine
President:
R.AdronHarris,Ph.D. President:
Vice President: AnneGeller,M.D.
IvanDiamond,M.D.,Ph.D. President-Elect:
Secretary: DavidE.Smith,M.D.
CarrieL.Randall,Ph.D. Secretary:
Treasurer: LynnHankes,M.D.
JamesD.Beard,Ph.D. Treasurer:
ImmediatePastPresident: WilliamB.Hawthorne,M.D.
FloydBloom,M.D. ImmediatePastPresident:
AnthonyB.Radcliffe,M.D.
BoardofDirectors:
HenriBegleiter,M.D.,Ph.D. Boardof Directors
FloydBloom,M.D.
Directors-at-large:
JohnCrabbe,Ph.D.
MargaretBean-Bayog,M.D.
V.GeneErwin,Ph.D. LeClairBissell, M.D.
Harold Holder,Ph.D. SheilaB.Blume, M.D.
StevenW.Leslie,Ph.D.
StanleyE.Gitlow,M.D.
Ting-KaiLi,M.D.
ChristineL.Kasser,M.D.
OscarParsons,Ph.D.
Max A. Schneider,M.D.
TinaVanderveen,Ph.D.
G.DouglasTalbott,M.D.
JoanneWeinberg,Ph.D.
RegionalDirectors:
MarcGalanter,M.D.
P.JosephFrawley, M.D.
AlanA.Wartenberg, M.D.
BruceK.Branin,D.O.
Richard A.Beach,M.D.
AndreaG.Barthwell,M.D.
J.ThomasPayte,M.D.
WalterE.Byrd, M.D.
RayP.Baker, M.D.
Contributors
KimberlyT. Ackerman,California School of Professional Psychology, Los
Angeles Campus, Alhambra, California 91803-1360
Catherine R. Ager, Institute of Health and Aging, Department of Social and
Behavioral Sciences, UniversityofCalifornia, San Francisco, California 94143
Andrea G. Barthwell, Interventions, Chicago, Illinois 60605
Fred Beauvais, Tri-Ethnic Center for Prevention Research, Department of
Psychology, Colorado State University, Fort Collins, Colorado 80523
Linda J. Beckman, California School of Professional Psychology, Los Angeles
Campus, Alhambra, California 91803-1360
Betty A. Blanchard, Department of Pathology and Anatomical Studies,
School of Medicine, University of Missouri, Columbia, Missouri 65212
Frederic C. Blow, University of Michigan Alcohol Research Center, Ann Ar-
bor, Michigan 48108-3318
Terry C. Blum, School of Management, Georgia Institute of Technology,
Atlanta, Georgia 30332-0520
Karen T. Britton, Department of Psychiatry, VA Medical Center and Univer-
sity of California, San Diego, California 92161
Michelle D. Brot, Department of Neuropharmacology, Scripps Research In-
stitute, La Jolla, California 92037
James H. Carter, Department of Psychiatry, Duke University Medical Center,
Durham, North Carolina 27710
Richard A. Deitrich, Department of Pharmacology, Alcohol Research Center,
University of Colorado Health Sciences Center, Denver, Colorado 80262
William R. Downs, Center for the Study of Adolescence, University of
Northern Iowa, Cedar Falls, Iowa 50614
Mary C. Dufour, Division of Biometry and Epidemiology, National Institute
on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville,
Maryland 20892
vii
viii Contributors
Ruth W. Edwards, Tri-Ethnic Center for Prevention Research, Department of
Psychology, Colorado State University, Fort Collins, Colorado 80523
Heidi P. Ferrer, Institute of Health and Aging, Department of Social and
Behavioral Sciences, University of California, San Francisco, California 94143
Kaye Middleton Fillmore, Institute of Health and Aging, Department of
Social and Behavioral Sciences, University of California, San Francisco, Cali-
fornia 94143
Richard K. Fuller, Division of Clinical and Prevention Research, National
institute on Alcohol Abuse and Alcoholism, National Institutes of Health,
Rockville, Maryland 20892
Judith S. Gavaler, Oklahoma Medical Research Foundation, and Oklahoma
Transplantation Institute, Baptist Medical Center, Oklahoma City, Oklahoma
73112
Susan Wagner Glenn, Department of Psychiatry and Behavioral Sciences,
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
73104
Stanley D. Glick, Department of Pharmacology and Toxicology, Albany
Medical College, Albany, New York 12210
Jacqueline M. Golding, Institute of Health and Aging, Department of Social
and Behavioral Sciences, University of California, San Francisco, California
94143
Edith S. Lisansky Gomberg, Department of Psychiatry, Alcohol Research
Center, University of Michigan, Ann Arbor, Michigan 48104
Edward Gottheil, Department of Psychiatry and Human Behavior, Thomas
Jefferson University, Philadelphia, Pennsylvania 19107
Ellen F. Gottheil, Department of Psychiatry and Behavioral Sciences, Univer-
sity of Washington Medical School, Seattle, Washington 98195
Eileen M. Harwood, Institute for Behavioral Research, University of Georgia,
Athens, Georgia 30602-2401
Shirley Y. Hill, Alcohol and Genetics Research Program, Department of Psy-
chiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylva-
nia 15213
Byron C. Jones, Program in Biobehavioral Health, Pennsylvania State Univer-
sity, University Park, Pennsylvania 16802-6508
Contributors ix
Steven Kneip, Institute of Health and Aging, Department of Social and Be-
havioral Sciences, University of California, San Francisco, California 94143
George F. Koob, Department of Neuropharmacology, Scripps Research Insti-
tute, LaJolla, California92037
Francine E. Lancaster, Department of Biology, Texas Woman's University,
Denton, Texas 76204
E. Victor Leino, Institute of Health and Aging, Department of Social and
Behavioral Sciences, University of California, San Francisco, California 94143
Gerald E. McClearn, Department of Biobehavioral Health and Center for
Developmental and Health Genetics, Pennsylvania State University, Univer-
sity Park, Pennsylvania 16802
Brenda A. Miller, Research Institute on Addictions, Buffalo, New York 14203
Sara Jo Nixon, Department of Psychiatry and Behavioral Sciences, University
of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104
Alfonso Paredes, Residential Treatment Center, West Los Angeles Veterans
Administration Medical Center, University of California School of Medicine,
Los Angeles, California 90024
Sylvia Rodriquez-Andrew, College of Social Work, San Jose State University,
San Jose, California 95192
Paul M. Roman, Institute for Behavioral Research, University of Georgia,
Athens, Georgia 30602-2401
Beatrice A. Rouse, Office of Applied Studies, Substance Abuse and Mental
Health Services Administration, Rockville, Maryland 20857
Laura Schmidt, Alcohol Research Group and Department of Sociology, Uni-
versity of California, Berkeley, California 94709
Carlisle Shoemaker, Institute of Health and Aging, Department of Social and
Behavioral Sciences, University California, San Francisco, California 94143
Holly S. Thomasson,Eli Lilly and Company, Lilly Laboratory for Clinical
Research, Wishard Memorial Hospital, Indianapolis, Indiana 46202
Pamela Jumper Thurman, Tri-Ethnic Center for Prevention Research, Depart-
ment of Psychology, Colorado State University, Fort Collins, Colorado 80523
x Contributors
Patricia F. Waller, University of Michigan Transportation Research Institute,
Ann Arbor, Michigan 48109-2150
Constance Weisner, Alcohol Research Group and School of Public Health,
University of California, Berkeley, California 94709
Keith E. Whitfield, Program in Biobehavioral Health, Pennsylvania State
University, University Park, Pennsylvania 16802-6508
Sharon C. Wilsnack, Department of Neuroscience, University of North Dako-
ta School of Medicine, Grand Forks, North Dakota 58202
Richard W. Wilsnack, Department of Neuroscience, University of North Da-
kota School of Medicine, Grand Forks, North Dakota 58202
Preface
From the Presidentof the Research Societyon Alcoholism
This twelfth volume of the Recent Developments in Alcoholism series highlights
the remarkable evolution of alcoholism research during the past few years.
The importance of gender in alcohol actions and consequences is finally re-
ceiving the attention it deserves. Furthermore, epidemiological, clinical, and
psychosocial approaches are assuming increasing importance in alcohol re-
search and investigators on the leading edge are beginning to integrate these
formerly segregated approaches. I am impressed at how the content of these
volumes reflects the changes in the Research Society on Alcoholism: our
membership is increasingly female and the diversity of research interests has
grown even more rapidly than our Society.
From the viewpoint of a basic scientist, gender differences are critically
important because they provide clues to the biological and thus genetic basis
of alcohol actions. The remarkably consistent observations that women drink
less than men but are more sensitive to harmful actions of alcohol should
provide a powerful approach to dissecting out the factors that contribute to
both consumption and organ damage. Section II presents the physiological
data on gender differences in alcohol action as well as the genetic underpin-
ning of these differences. The application of animal genetic and neurochemi-
cal approaches shows that the strong foundation established by so many
alcohol researchers during the past decade will be fruitfully applied to analy-
sis of gender differences. Section II, on epidemiology, raises the important,
and doubly neglected, area of alcoholism in older women. Many of the issues
presented in the epidemiological and sociocultural sections will have impor-
tant consequences for treatment and are discussed in Section III.
The editor and associate editors deserve thanks and congratulations from
our field for providing excellent coverage of such timely topics.
R. Adorn Harris, Ph.D.
President, Research Society on Alcoholism
From the President of the American Society of Addiction Medicine
The American Society of Addiction Medicine is honored to be cosponsoring
with the Research Society on Alcoholism the current issue of Recent Develop-
ment in Alcoholism, Volume 12, Alcoholism and Women. It is only in the last
xi