Recent Advances in Breast Imaging, Mammography, and Computer-Aided Diagnosis of Breast Cancer

1011 Pages·2006·63.77 MB·English

by  Jasjit S. Suri

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RECENT ADVANCES IN
Breast Imaging, Mammography,
and Computer-Aided Diagnosis
of Breast Cancer
RECENT ADVANCES IN
Breast Imaging, Mammography,
and Computer-Aided Diagnosis
of Breast Cancer
Jasjit S. Suri
Rangaraj M. Rangayyan
Editors
Bellingham, Washington USA
Library of Congress Cataloging-in-Publication Data

Recent advances in breast imaging, mammography, and computer-aided diagnosis of breast
cancer/ Jasjit S. Suri, Rangaraj M. Rangayyan, editors.
p. cm.
Includes bibliographical references and index.
ISBN 0-8194-6081-8
1. Breast–Radiography. 2. Breast–Imaging. 3. Breast–Cancer–Diagnosis. [DNLM: 1. Breast
Neoplasms–diagnosis. 2. Diagnosis, Computer-Assisted–methods. 3. Diagnostic Imaging–
methods. 4. Mammography–methods. WP 870 R295 2006] I. Suri, Jasjit S. II. Rangayyan,
Rangaraj M. III. Society of Photo-optical Instrumentation Engineers.

RC280.B8R43 2006
616.99'4490757–dc22 2005037907

Published by

SPIE—The International Society for Optical Engineering
P.O. Box 10
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Copyright © 2006 The Society of Photo-Optical Instrumentation Engineers

All rights reserved. No part of this publication may be reproduced or distributed
in any form or by any means without written permission of the publisher.

The content of this book reflects the work and thought of the author(s).
Every effort has been made to publish reliable and accurate information herein,
but the publisher is not responsible for the validity of the information or for any
outcomes resulting from reliance thereon.

Printed in the United States of America.

Dr.JasjitS.SuridedicatesthisbooktohischildrenHarmanandNeha,hiswifeMalvika,
andhisdearfriendsandcollaboratorsallaroundtheworldwhohavemadethispossible.
Dr.RangarajM.Rangayyandedicatesthisbooktohisstudents,fellowresearchers,and
clinicalcollaborators.

Contents
List of Contributors / xvii
Preface / xxi
Acknowledgments / xxxi
Chapter 1. The Subgross Morphology of Normal and Pathologically
Altered Breast Tissue / 1
TiborTot
1.1 Introduction / 2
1.2 SubgrossBreast Anatomy / 3
1.3 The Normal Mammogram / 15
1.4 In Situ Developmentof Malignant Tumors / 20
1.5 Invasive Carcinomas / 30
1.6 Time as MorphologicFactor / 45
References / 47
Chapter 2. Fundamentals of Achieving Functional and Anatomical
Imaging with Breast MRI: Physical and Clinical Concepts / 51
DeeH.Wu,AnnG.Archer,L.JillHast,BrendaElledge,DouglasBeall,
MaxWalter,SusanM.Edwards,HeatherR.Webb,BarryJ.Greer,
andErikaRubesova
2.1 Introduction / 52
2.2 Consequencesof Composition, Architectural, and Functional
Evaluation in Breast MR Imaging / 59
2.3 Breast Composition and Hormonal Influences (Fat, Ducts,
Secretions, and Breast Implants) / 60
2.4 Region of Interest Definition of Tumors / 63
2.5 Technological Fundamentalsof Breast MRI / 64
2.6 Summary / 102
Acknowledgments / 102
References / 103
Chapter 3. An Indexed Atlas of Digital Mammograms for
Computer-Aided Diagnosis of Breast Cancer / 109
HilaryAlto,RangarajM.Rangayyan,RamanB.Paranjape,
J.E.LeoDesautels,andHeatherBryant
vii
viii CONTENTS
3.1 Introduction / 110
3.2 Databasesof Mammograms / 111
3.3 The Indexed Atlas Concept / 112
3.4 Design of the University of Calgary Indexed Atlas of
Mammograms / 114
3.5 Use of Mobile Software Agents with the Indexed Atlas / 119
3.6 Discussion / 120
Acknowledgments / 122
References / 122
Chapter 4. Genetic Algorithms in CAD Mammography / 129
RenatoCampaniniandNicoLanconelli
4.1 Introduction / 130
4.2 CAD Critical Issues / 133
4.3 Genetic Algorithms: A Brief Overview / 136
4.4 GA for ParametersOptimization / 141
4.5 GA for Feature Selection / 151
References / 156
Chapter 5. Mammographic Mass Detection by Robust Learning
Algorithms / 159
AizeCao,QingSong,XuleiYang,ZhiminWang,andYanShui
5.1 Introduction / 160
5.2 Robust Information Clustering for Automatic Mass Detection / 161
5.3 Vicinal Support Vector Machine for Mass-Pattern Analysis / 178
References / 192
Chapter 6. Analysis of Bilateral Asymmetry in Mammograms via
Directional Filtering with Gabor Wavelets / 197
RicardoJ.Ferrari,RangarajM.Rangayyan,J.E.LeoDesautels,
andAnnieF.Frère
6.1 Introduction / 198
6.2 Bilateral Asymmetry in Mammograms / 200
6.3 Construction of Gabor Wavelets / 200
6.4 Directional Analysis / 205
6.5 Analysis of Asymmetry in Mammograms / 211
6.6 Results / 215
6.7 Discussion and Conclusions / 224
Acknowledgments / 224
References / 224