Quality Controls in Allergy Diagnosis

69 Pages·2009·4.82 MB·English

Quality Controls in Allergy
Diagnosis
Alistair Crockard
Royal Hospitals
Belfast
Northern Ireland
Quality Controls in Allergy
Diagnosis
• What do we want?
• What can be controlled?
• What can be achieved?
What do we want?
1. A process that ensures that:
the results generated are correct
What do we want?
1. A process that ensures that:
the results generated are correct
QUALITY CONTROL
What do we want?
2. A process that ensures:
the quality of results is consistent and in line
with those determined for recognised
reference material (standards)
What do we want?
2. A process that ensures:
the quality of results is consistent and in line
with those determined for recognised
reference material (standards)
QUALITY ASSESSMENT
What do we want?
3. A process that ensures:
the correcttest is carried out on the correct
sample and the correctresult, with the
correctinterpretation, is delivered to the
correctperson at the correcttime.
What do we want?
3. A process that ensures:
the correcttest is carried out on the correct
sample and the correctresult, with the
correctinterpretation, is delivered to the
correctperson at the correcttime.
QUALITY ASSURANCE
What do we want?
4. Guidelines:
CLSI Approved Guidelines I/LA20-4 (1997)
“Evaluation methods and analytical performance characteristics
of immunology assays for human IgE antibodies of defined
specificities”
2nd Edition due late 2008
www.clsi.org
What can be controlled?
Steps in the Analytical Process