Table Of ContentSubject  index  of volume  108 
Abstinence  495  Chick  235  Facilitation  443 
Acetylcholine  417  Chlordiazepoxide  72, 263  Fear  352 
Acetylcholinesterase-inhibitor  103  Chlorpromazine  289, 338, 345  FG 7142  185, 205 
Acoustic startle response  40, 189  Cholinomimetics  11  Flumazenil  147 
ACTH  27  Chronic cocaine treatment  263  Fluphenazine  338 
Addiction  218, 397, 408  Chronic exposure  51  Food consumption  501 
Adrenalectomy  27  Chronic treatment  33  FR  115 
a-Adrenergic antagonists, atipamezole  Cigarette  452 
229  Cigarette smoking  1, 460, 495, 512  GABA  196 
a-Adrenergic receptor  313  Clonazepam  131  Genetic  136 
a,-Adrenergic antagonists,  prazosin  Clonidine  159, 283  Gepirone  289 
229  Clovoxamine  327  Guanfacine  159 
a&2-Adrenergic agonists, dexmedetomi-  Cocaine  256, 295 
dine  229  Cocaine abuse  289  Haloperidol  141, 338 
Aerosol  519  Cocaine discontinuation  263  5-HT. receptor  387 
Aggression  177, 196, 276  Cold pressor pain  60  5-HT3  333 
Agonistic behavior  196  Conditioning  218  5-HT,,  123, 320 
Alcohol  276  Conflict schedule  185  5-HT,, agonists  47 
Alternative reinforcer  295  Consolidation  448  5-HT,, receptor  110 
Alzheimer's disease  103, 480, 485  Continuous performance task reaction  5-HT,, receptors  85, 380 
Ambulatory activity  271  time  437  5-HT,,  123 
Amitriptyline  327  Controlled dosing  519  Human  103, 225, 345, 371 
Amygdala  189  Corticosteroids  11  Human brain  16 
Analgesia  60  Corticosterone  27, 33  Humans  51, 60 
Animal behavior  196  Cortisol  153, 313 
Animal model  352  Cortisol response  519  Idazoxan  313 
Animal model of alcoholism  136  Cotinine  507  Imipramine  23 
Animal models of anxiety  205  Cue learning  147  In vitro autoradiography  16 
Antagonist  320  "C  16  Individuality  67 
Anticholinergic  327  Infantile stimulation  170 
Antidepressants  23, 93  Information  processing  485 
Defensive behavior  205 
Antidepressants  327  Inhibitory avoidance learning  131 
Demand  1 
Antiepileptic drugs  131  Insomnia  67 
Dementia  103 
Antipredator defense  352  Inverse agonist  185 
Dependence  218, 333, 408, 507 
Antipsychotics  98 
Depression  93 
Anxiety  213, 313, 333, 352, 387  Kappa opioid receptor  235 
Desipramine  363 
Anxiogenic property  205  Ketanserin  27 
Development  256 
Anxiolysis  229  Ketanserine  210 
Diazepam  131, 147, 301, 371 
Apomorphine  47, 72, 367 
Discrete-trials choice  295 
Arginine-vasopressin  225  Late luteal phase dysphoric disorder 
DO!  27 
Arousal  456  153 
Dopa decarboxylase  98 
Attention  159, 485  Lateralisation  473 
Dopamine  72, 177, 189, 256, 345, 367 
Aversion  110  Learning  345, 480 
Dopamine antagonists  289 
Lithium  93 
Dose-related  460 
Locomotion  177, 196 
Behavioral economics  1  Doxazosine  283 
Locomotor activity  352, 367 
Behaviour  283  DRL  115 
Locus coeruleus  23 
Benzodiazepine  72, 333  Drug abuse  60 
Long-term memory  448 
Benzodiazepine agonist, midazolam  Drug discrimination  85 
Lorazepam  345, 371 
229  Drug interactions  115 
Benzodiazepine antagonist, flumazenil  Drug selfadministration  1 
m-chlorophenylpiperazine  225 
229  Drug stimulus exposure  495 
MCPP  320 
Benzodiazepine physical dependence  Dynorphin  235 
Mecamylamine  417, 480 
301  D2 receptors  47 
Memory  159, 235, 327, 345, 371, 417, 
Benzodiazepine receptors  16 
443, 452 
Benzodiazepines  147, 196, 248, 371 
EEG  473  Memory improvement  11 
Beta-CCE  205 
Electroconvulsive treatment  367  Mesolimbic dopamine system  141 
Blood pressure  313 
Elevated  plus-maze  229  Methamphetamine sensitivity  271 
Body weight  501 
Emotional reactivity  170  MHPG  313 
Brain levels  338 
B-endorphin  153  Mice  131, 271, 276, 367 
Bromperidol  338 
Ethanol  301  Microeconomics  1 
Bungarotoxin-receptors  33 
Ethanol  intake  136  MK-801  115, 271, 352, 367 
Buspirone  289, 380 
Etoperidone  320  Monkey brain  16 
Euphoriant effects  460  Mood  60 
Caffeine  51  Examination  anxiety  456  Morphine  40, 60, 147, 283 
Carbamazepine  131  Excitatory amino acid  110  Morphine-6-glucuronide  60 
Carbon monoxide  466  Exploration  170  Morris water maze  147
Subject  index  of volume  108 
Abstinence  495  Chick  235  Facilitation  443 
Acetylcholine  417  Chlordiazepoxide  72, 263  Fear  352 
Acetylcholinesterase-inhibitor  103  Chlorpromazine  289, 338, 345  FG 7142  185, 205 
Acoustic startle response  40, 189  Cholinomimetics  11  Flumazenil  147 
ACTH  27  Chronic cocaine treatment  263  Fluphenazine  338 
Addiction  218, 397, 408  Chronic exposure  51  Food consumption  501 
Adrenalectomy  27  Chronic treatment  33  FR  115 
a-Adrenergic antagonists, atipamezole  Cigarette  452 
229  Cigarette smoking  1, 460, 495, 512  GABA  196 
a-Adrenergic receptor  313  Clonazepam  131  Genetic  136 
a,-Adrenergic antagonists,  prazosin  Clonidine  159, 283  Gepirone  289 
229  Clovoxamine  327  Guanfacine  159 
a&2-Adrenergic agonists, dexmedetomi-  Cocaine  256, 295 
dine  229  Cocaine abuse  289  Haloperidol  141, 338 
Aerosol  519  Cocaine discontinuation  263  5-HT. receptor  387 
Aggression  177, 196, 276  Cold pressor pain  60  5-HT3  333 
Agonistic behavior  196  Conditioning  218  5-HT,,  123, 320 
Alcohol  276  Conflict schedule  185  5-HT,, agonists  47 
Alternative reinforcer  295  Consolidation  448  5-HT,, receptor  110 
Alzheimer's disease  103, 480, 485  Continuous performance task reaction  5-HT,, receptors  85, 380 
Ambulatory activity  271  time  437  5-HT,,  123 
Amitriptyline  327  Controlled dosing  519  Human  103, 225, 345, 371 
Amygdala  189  Corticosteroids  11  Human brain  16 
Analgesia  60  Corticosterone  27, 33  Humans  51, 60 
Animal behavior  196  Cortisol  153, 313 
Animal model  352  Cortisol response  519  Idazoxan  313 
Animal model of alcoholism  136  Cotinine  507  Imipramine  23 
Animal models of anxiety  205  Cue learning  147  In vitro autoradiography  16 
Antagonist  320  "C  16  Individuality  67 
Anticholinergic  327  Infantile stimulation  170 
Antidepressants  23, 93  Information  processing  485 
Defensive behavior  205 
Antidepressants  327  Inhibitory avoidance learning  131 
Demand  1 
Antiepileptic drugs  131  Insomnia  67 
Dementia  103 
Antipredator defense  352  Inverse agonist  185 
Dependence  218, 333, 408, 507 
Antipsychotics  98 
Depression  93 
Anxiety  213, 313, 333, 352, 387  Kappa opioid receptor  235 
Desipramine  363 
Anxiogenic property  205  Ketanserin  27 
Development  256 
Anxiolysis  229  Ketanserine  210 
Diazepam  131, 147, 301, 371 
Apomorphine  47, 72, 367 
Discrete-trials choice  295 
Arginine-vasopressin  225  Late luteal phase dysphoric disorder 
DO!  27 
Arousal  456  153 
Dopa decarboxylase  98 
Attention  159, 485  Lateralisation  473 
Dopamine  72, 177, 189, 256, 345, 367 
Aversion  110  Learning  345, 480 
Dopamine antagonists  289 
Lithium  93 
Dose-related  460 
Locomotion  177, 196 
Behavioral economics  1  Doxazosine  283 
Locomotor activity  352, 367 
Behaviour  283  DRL  115 
Locus coeruleus  23 
Benzodiazepine  72, 333  Drug abuse  60 
Long-term memory  448 
Benzodiazepine agonist, midazolam  Drug discrimination  85 
Lorazepam  345, 371 
229  Drug interactions  115 
Benzodiazepine antagonist, flumazenil  Drug selfadministration  1 
m-chlorophenylpiperazine  225 
229  Drug stimulus exposure  495 
MCPP  320 
Benzodiazepine physical dependence  Dynorphin  235 
Mecamylamine  417, 480 
301  D2 receptors  47 
Memory  159, 235, 327, 345, 371, 417, 
Benzodiazepine receptors  16 
443, 452 
Benzodiazepines  147, 196, 248, 371 
EEG  473  Memory improvement  11 
Beta-CCE  205 
Electroconvulsive treatment  367  Mesolimbic dopamine system  141 
Blood pressure  313 
Elevated  plus-maze  229  Methamphetamine sensitivity  271 
Body weight  501 
Emotional reactivity  170  MHPG  313 
Brain levels  338 
B-endorphin  153  Mice  131, 271, 276, 367 
Bromperidol  338 
Ethanol  301  Microeconomics  1 
Bungarotoxin-receptors  33 
Ethanol  intake  136  MK-801  115, 271, 352, 367 
Buspirone  289, 380 
Etoperidone  320  Monkey brain  16 
Euphoriant effects  460  Mood  60 
Caffeine  51  Examination  anxiety  456  Morphine  40, 60, 147, 283 
Carbamazepine  131  Excitatory amino acid  110  Morphine-6-glucuronide  60 
Carbon monoxide  466  Exploration  170  Morris water maze  147
Vil 
Motor activity  177, 196  Place learning  147  Sleep  67, 213 
mRNA levels  98  Platelet  210  Sleep-wakefulness  263 
Positron emission tomography  16, 380  Slow wave sleep  387 
N-allylnormetazocine  115  Prefrontal cortex  159  Smokers  519 
Naloxone  40, 141, 147  Premenstrual  symptoms  153  Smoking  408, 432, 437, 448, 456, 473 
Naltrexon  79  Prenatal exposure  256  Snuff  507 
Nasal nicotine spray  512  Prepulse inhibition  189  Social status  276 
Nicotine  397, 408, 417, 443, 448, 452,  Progressive-ratio  295  Spinal cord  123 
456, 460, 466, 473, 480, 485, 501,  Proponent process  79  Spinal reflexes  123 
507, 519  Psychomotor performance  432  Statistical  parametric mapping  380 
Nicotine effects  512  Psychopharmacological effects  466  Stress  23, 276, 456 
Nicotine gum  432  Punishment  185  Striatum  189 
Nicotine pharmacokinetics  512  Subjective effects  51 
Nicotine regulation  1  Quazepam  248  Subjective response  519 
Nicotine replacement treatment  512  Quinpirole  72, 256  Substance withdrawal syndrome  67 
Nicotine-tolerance  33  Sulpiride  72 
Nicotinic  417  Radial arm maze  72  (+) S-20499  47 
Nicotinic cholinergic-stress  33  Rat  40, 47, 147, 185, 229, 263, 283 
NMDA antagonist  352  Rat brain  363  Tar  466 
NMDA receptor  367  Rats  320  Tobacco use  397 
Nociception  123  Rebound  insomnia  67, 248  Tolerance  51, 218 
Non-match-to-sample task  72  Reinforcement  51  Tomography, single photon emission 
Nootropics  11  Reinstatement  79  computed  103 
nor-binaltorphimine  235  Relapse  79, 218, 495  Trazodone  320 
Norepinephrine  313  Repeated administration  271  Triazolam  67, 301 
Nucleus accumbens  189  Repetition priming  371  Tricyclics  327 
RFT (Reciprocal  Forepaw Treading)  Tryon rats  136 
8-OH-DPAT  85  320  Tryptophan  60 
Opiate  218  Rhesus monkey  289, 295  Tyrosine hydroxylase  23, 98 
Opiates  177  Ritanserin  213, 263, 387  ['?5!] Tyr’ '-somatostatin  binding sites 
Opioid  218  Ro 15-4513  16  363 
Opioid peptides  235  Roman high- and low-avoidance rats 
Opioid receptor  141  170  UK-14.304  283 
Opioids  79, 147  Unit price  1 
Opponent process  79  Schedule-controlled  behavior  115  U-50,488  235 
Oral self-administration  301  Schizophrenia  98 
Orbital cortex  189  SCH23390  72  Water consumption  501 
Selective breeding  136  Wet-dog shakes  27 
Peck-avoidance  235  Self-administration  79, 295  Withdrawal  40, 177, 218, 283 
Penile erections  47  Self-administration  of drugs  289  Withdrawal-deficit  437 
Periaqueductal gray  110  Sensorimotor gating  189  Withdrawal  effects  213 
Perinatal flumazenil  (Ro 15-1788)  170  Serotonin  60, 93, 110, 123, 153, 225,  Working/episodic  memory  72 
FET  16  320 
Pharmacological  challenge  380  Serotonin  receptors  210  Yawning  47 
Phencyclidine  115  Serotonin-2  (5-HT2 ) binding site  27  Yohimbine  313 
Phenylpropanolamine  501  Sex differences  352 
Phenytoin  131  Short-term memory  485  Zacopride  333 
Physical dependence  40, 51  SKF38393  72  Zolpidem  248 
Physiological  response  519  SKF104078  159  Zopiclone  248