Proteolytic Enzymes in Coagulation, Fibrinolysis, and Complement Activation Part B: Complement Activation, Fibrinolysis, and Nonmammalian Blood Coagulation Factors and Inhibitors

456 Pages·1993·8.373 MB·English

by  Laszlo Lorand, Kenneth G. Mann (Eds.)

Contributors to Volume 223
Article numbers are ni sesehtnerap gniwollof eht seman of .srotubirtnoc
snoitailiffA listed era .tnerruc
NoBuo AOKI (11), The First Department of Foundation, Cincinnati, Ohio 45229, and
Internal Medicine, Tokyo Medical and Department of Pediatrics, University of
Dental University, Tokyo 113, Japan Cincinnati College of Medicine, Cincin-
G~RARD J. ARLAUD (4), lnstitut de Biologic nati, Ohio 92254
Structurale, Laboratoire d'Enzymologie A. J. DAY (1), Department of Biochemistry,
Mol~culaire, 38027 Grenoble Cedex ,1 University of Oxford, Oxford OXI 3QU,
France United Kingdom
KULWANT S. AULAK (6), Division of Ne- ALISTER W. DODDS (3), Medical Research
phrology, Children's Hospital Research Council, Immunochemistry Unit, Depart-
Foundation, Cincinnati, Ohio 45229, and ment of Biochemistry, University of -xO
Department of Pediatrics, Univeristy of ford, Oxford OXI 3QU, United King-
Cincinnati College of Medicine, Cincin- dom
nati, Ohio 92254 CHRISTOPHER T. DUNWIDDIE (18), Depart-
SCOTT R. BARNUM (5), Department of Mi- ment of Cardiovascular Biology, Rhone-
crobiology, University of Alabama at Bir- Poulenc Rorer, Collegeville, Pennsylva-
mingham, Birmingham, Alabama 49253 ain 62491
DETLEV BEHNKE (9), Zentralinstitutfiir Mi- YAJ M. EDELBERG (17), Department of
krobiologie und Experimentelle Thera- Medicine, Massachusetts General, Bos-
pie, D-6900 Jena, Germany ton, Massachusetts 41120
NIELS BEHRENDT (13, 14), ehT Finsen Lab- VINCENT ELLIS (14), ehT Finsen Labora-
oratory, Rigshospitalet, DK-2100 Copen- tory, Rigshospitalet, DK-2100 Copenha-
hagen ,O Denmark gen ,O Denmark
JOHN J. BISSLER (6), Division of Nephrol- JAN J. ENGHILD (7), Pathology Depart-
ogy, Children's Hospital Research Foun- ment, Duke University Medical Center,
dation, Cincinnati, Ohio 99254 Durham, North Carolina 01772
FRANCIS J. CASTELLINO (8, 10), Thrombo- M. FONTAINE (1), INSERM-Unit~ ,87 03267
lytics Venture Group, Abbott Laborato- Bois-Guillaume, France
ries, Abbott Park, Illinois 60044 PAUL A. FRIEDMAN (15, 18), Merck Re-
~IRIS~ID COLLEN (Introduction, 12), Center search Laboratories, West Point, Penn-
for Molecular and Vascular Biology, Uni- sylvania 68491
versity of Leuven, Leuven B-3000, Bel- STEPHEN J. GARDELL (15), Department of
gium Biological Chemistry, Merck Research
KELD DANe (13, 14), The Finsen Labora- Laboratories, West Point, Pennsylvania
tory, Rigshospitalet, DK-2100 Copenha- 68491
gen ,~( Denmark DIETER GERLACH (9), Zentralinstitutfiir Mi-
DONALD J. DAVIDSON (8, 10), Department krobiologie und Experimentelle Therapie,
of Chemistry and Biochemistry, Univer- 0096-D Jena, Germany
sity of Notre Dame, Notre Dame, Indiana RICHARD A. HARRISON (6), Molecular lm-
65564 munopathology Unit, Medical Research
ALVIN E. DAVIS III (6), Division of Ne- Council, Cambridge 2BC 2QH, United
phrology, Children's Hospital Research Kingdom
ix
X CONTRIBUTORS TO VOLUME 223
RYUJl OTOMIHSAH (22), Department of -iB IHSUSTAT MUTA (20, 21,22), Department of
ology, Faculty of Science, Kyushu Uni- Biology, Faculty of Science, Kyushu Uni-
versity, Fukuoka-812, Japan versity, Fukuoka-812, Japan
UKASNIHS HIROSAWA (11), ehT First De- IRONAKAT ARUMAKAN (20, 21, 22), ehT In-
partment of Internal Medicine, Tokyo stitute for Enzyme Research, ehT Univer-
Medical and Dental University, Tokyo sity of Tokushima, Tokushima 770, Japan
,311 Japan NORIKAZU NISHINO (24), Department of
GUNILLA NESNAH-REYCH (13), ehT Finsen Applied Chemistry, Faculty of Engineer-
Laboratory, Rigshospitalet, DK-2100 -oC ing, Kyushu Institute of Technology, Ki-
penhagen ~, Denmark takyushu 804, Japan
IKAADAS lWANAGA (20, 21, 22, 23, 24, 25), NEELHTAK F. NOLAN (Introduction, 2),
Department of Biology, Faculty of Sci- Medical Research Council, Immuno-
ence, Kyushu University, Fukuoka 812, chemistry Unit, Department of Biochem-
Japan istry, University of Oxford, Oxford 1XO
J. MICHAEL KCIRTAPEIK (5), Department of 3QU, United Kingdom
Medicine, University of Alabama at Bir- OIHSOT ODA (21), Department of Biology,
mingham, Birmingham, Alabama 49253 Faculty of Science, Kyushu University,
NOOJ-GNUOY LEE (17), Department of Pa- Fukuoka-812, Japan
thology, Duke University Medical Center, USTOMAT OMORI-SATOH (24), Department
Durham, North Carolina 01772 of Biochemistry and Cell Biology, Na-
H. ROGER LIJNEN (Introduction, 12), Center tional Institute of Health, Toyama ,1-32-1
Shinjuku-ku, Tokyo 162, Japan
for Molecular and Vascular Biology, Uni-
versity of Leuven, Leuven B-3000, Bel- EROTAVLAS V. PIZZO (17), Department of
gium Pathology, Duke University Medical Cen-
EDWIN L. MADISON (16), Department of ter, Durham, North Carolina 01772
Vascular Biology, Scripps Research Insti- LEAHCIM PLOUG (13), ehT Finsen Labora-
tute, La Jolla, California 73029 tory, Rigshospitalet, DK-2100 Copenha-
JOHN M. ERONAGARAM (19), Department of gen ,O Denmark
Biological Research, Biogen, Inc., Cam-
SEMAJ T. RADEK (8), Department of Bio-
bridge, Massachusetts 24120
chemistry, Molecular Biology and Cell Bi-
SEMAJ MCLINDEN (10), Department of Mo- ology, Northwestern University, Evan-
lecular Biology, American Biogenetic Sci-
ston, Illinois 80206
ences, Notre Dame, Indiana 65564
KENNETH B. M. REID (Introduction, 2),
UMASO MIU~ (11), ehT First Department
Medical Research Council, lmmuno-
of Internal Medicine, Tokyo Medical and
chemistry Unit, Department of Biochem-
Dental University, Tokyo 113, Japan
istry, University of Oxford, Oxford 1XO
IKUYIHSOT MIYATA (24), Laboratory of 3QU, United Kingdom
Thrombosis Research, National Cardio-
vascular Center, Research Institute, EBBE RCNNE (13), The Finsen Laboratory,
Rigshospitalet, DK-2100 Copenhagen ,O
Suita 565, Japan
Denmark
B. E. MOFEATT (1), Medical Research
Council, lmmunochemistry Unit, Depart- ELLIOT ROSEN (10), Department of Gene
ment of Biochemistry, University of -xO Expression, American Biogenetic Sci-
ford, Oxford 1XO 3QU, United Kingdom ences, Notre Dame, Indiana 65564
IHSAKAT MORITA (20, 21, 22), Department GuY NESEVEAS (7), Pathology Department,
of Biochemistry, MeUi College of Phar- Duke University Medical Center, Dur-
macy, Tokyo-188, Japan ham, North Carolina 27710
CONTRIBUTORS TO VOLUME 223 xi
JOSEPH F. SAMBROOK (16), Department of FUMINORI TOKUNAGA (20, 25), Department
Biochemistry, University of Texas, South- of Life Science, Faculty of Science, Hi-
western Medical Center at Dallas, Dallas, meji Institute of Technology, Harima Sci-
Texas 53257 ence Park City, Kamigori, Hyogo ,21-876
R. B. SIM (1), Medical Research Council, Japan
lmmunochemistry Unit, Department of THANG TRIEU I (9), Protein Studies Pro-
Biochemistry, University of Oxford, -xO gram, Oklahoma Medical Research
ford 1XO 3QU, United Kingdom Foundation, Oklahoma City, Oklahoma
STUART R. STONE (19), MRC Centre, Uni- 40137
versity of Cambridge, Cambridge 2BC
GEORGE P. VLASUK (18), Corvas Inter-
2TS, United Kingdom
national, Inc., San Diego, California
YOSHIHIKO SUMI (11), Biotechnology Re- 12129
search Laboratory, Te(iin Limited, Tokyo
JOHN E. VOLANAKIS (5), Department of
,191 Japan
Medicine, University of Alabama at Bir-
HIROYUKI TAKEYA (24), Department of Mo- mingham, Birmingham, Alabama 49253
lecular Biology, Mie University School of
Medicine, Tsu, Mie 514, Japan LLOYD WAXMAN (18), Merck Research
Laboratories, West Point, Pennsylvania
SnIGENORI TANAKA (23), Research Labora-
68491
tory, Seikagaku Corporation, Higashi-
yamato City, Tokyo-207, Japan TIMOTHY N. YOUNG (17), Department of
JORDAN TANG (9), Protein Studies Pro- Pathology, Duke University Medical Cen-
gram, Oklahoma Medical Research ter, Durham, North Carolina 01772
Foundation, Oklahoma City, Oklahoma KAMYAR ZAHEDI (6), Division of Nephrol-
40137 ogy, Children's Hospital Research Foun-
NICOLE M. THIELENS (4), Institut de Biolo- dation, Cincinnati, Ohio 45229, and De-
gie Structurale, Laboratoire d'Enzymolo- partment of Pediatrics, University of
gie Mol(culaire, 38027 Grenoble Cedex ,1 Cincinnati College of Medicine, Cincin-
France nati, Ohio 92254
i Deceased.
Preface
Originally, a single volume was planned to cover the field of Proteoly-
tic Enzymes in Coagulation, Fibrinolysis, and Complement Activation,
but it soon became evident that--related though these topics may be--the
material would have to be published in two parts. In this volume of
Methods in Enzymology (223, Part B) the important fields of complement
activation and fibrinolysis and the esoteric area of increasing pharmaco-
logical interest nonmammalian blood coagulation factors and inhibitors
are covered. Its companion Volume 222, Part A deals with mammalian
coagulation factors and inhibitors.
OLZSAL DNAROL
HTENNEK G. MANN
iiix
METHODS IN ENZYMOLOGY
EMULOV I. Preparation and Assay of Enzymes
Edited by SIDNEY P. KClWOLOC DNA NATHAN O. KAPLAN
EMULOV II. Preparation and Assay of Enzymes
Edited by SIDNEY P. COLOWICK DNA NATHAN O. KAPLAN
EMULOV III. Preparation and Assay of Substrates
Edited by SIDNEY P. COLOWICK DNA NATHAN O. KAPLAN
EMULOV IV. Special Techniques for the Enzymologist
Edited by SIDNEY P. COLOWICK DNA NATHAN O. KAPLAN
EMULOV V. Preparation and Assay of Enzymes
Edited by SIDNEY P. COLOWICK DNA NATHAN O. KAPLAN
EMULOV VI. Preparation and Assay of Enzymes (Continued)
Preparation and Assay of Substrates
Special Techniques
Edited by SIDNEY P. COLOWICK DNA NATHAN O. KAPLAN
EMULOV VII. Cumulative Subject Index
Edited by SIDNEY P. COLOWICK DNA NATHAN O. KAPLAN
EMULOV VIII. Complex Carbohydrates
Edited by ELIZABETH F. NEUFELD DNA GINSBURG VICTOR
VOLUME IX. etardyhobraC Metabolism
Edited by WILLIS A. WOOD
EMULOV X. Oxidation and Phosphorylation
Edited by RONALD W. KOORBATSE DNA MAYNARD E. PULLMAN
VOLUME XI. Enzyme Structure
Edited by C. H. W. HIRS
EMULOV XII. Nucleic Acids (Parts A and B)
Edited by LAWRENCE NAMSSORG DNA KIVIE MOLDAVE
EMULOV XIII. Citric Acid Cycle
Edited by J. M. NIETSNEWOL
VOLUME XIV. Lipids
Edited by J. M. NIETSNEWOL
EMULOV XV. Steroids and Terpenoids
Edited by RAYMOND B. CLAYTON
VOLUME XVI. Fast Reactions
Edited by KUSTIN KENNETH
VX
xvi SDOHTEM IN YGOLOMYZNE
VOLUME XVII. Metabolism of Amino Acids and Amines (Parts A and B)
Edited yb HERBERT TABOR DNA CELIA WHITE ROBAT
VOLUME XVIII. Vitamins and Coenzymes (Parts A, B, and C)
Edited yb DONALD B. McCORMICK DNA LEMUEL D. WRIGHT
VOLUME XlX. Proteolytic Enzymes
Edited yb GERTRUDE E. PERLMANN AND LASZLO LORAND
VOLUME XX. Nucleic Acids and Protein Synthesis (Part C)
Edited yb KIVIE MOLDAVE AND LAWRENCE NAMSSORG
VOLUME XXI. Nucleic Acids (Part D)
Edited by LAWRENCE GROSSMAN DNA KIVIE MOLDAVE
VOLUME XXII. Enzyme Purification and Related Techniques
Edited by WILLIAM B. JAKOBY
VOLUME XXIII. Photosynthesis (Part A)
Edited by ANTHONY SAN PIETRO
VOLUME XXIV. Photosynthesis and Nitrogen Fixation (Part B)
Edited yb ANTHONY SAN PIETRO
VOLUME XXV. Enzyme Structure (Part B)
Edited yb C. H. W. HIRS AND SERGE N. TIMASHEFF
VOLUME XXVI. Enzyme Structure (Part C)
Edited yb C. H. W. HIRS DNA SERGE N. TIMASHEFF
VOLUME XXVII. Enzyme Structure (Part D)
Edited yb C. H. W. HIRS DNA SERGE N. TIMASHEFF
VOLUME XXVIII. Complex Carbohydrates (Part B)
Edited yb VICTOR GINSBURG
VOLUME XXIX. Nucleic Acids and Protein Synthesis (Part E)
Edited yb LAWRENCE GROSSMAN DNA KIVIE MOLDAVE
VOLUME XXX. Nucleic Acids and Protein Synthesis (Part F)
Edited by KIVIE MOLDAVE DNA LAWRENCE NAMSSORG
VOLUME XXXI. Biomembranes (Part A)
Edited by SIDNEY FLEISCHER AND LESTER PACKER
VOLUME XXXII. Biomembranes (Part B)
Edited yb SIDNEY FLEISCHER DNA LESTER PACKER
VOLUME XXXIII. Cumulative Subject Index Volumes I-XXX
Edited yb MARTHA G. DENNIS DNA EDWARD A. DENNIS
VOLUME XXXIV. Affinity Techniques (Enzyme Purification: Part B)
Edited by WILLIAM B. JAKOBY DNA MEIR WILCHEK
VOLUME XXXV. Lipids (Part B)
Edited by JOHN M. LOWENSTEIN
METHODS IN ENZYMOLOGY xvii
EMULOV XXXVI. Hormone Action (Part A: Steroid Hormones)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMDRAH
EMULOV XXXVII. Hormone Action (Part B: Peptide Hormones)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMDRAH
EMULOV XXXVIII. Hormone Action (Part C: Cyclic Nucleotides)
Edited by JOEL G. NAMDRAH DNA BERT W. O'MALLEY
EMULOV XXXlX. Hormone Action (Part D: Isolated Cells, Tissues, and Organ
Systems)
Edited by JOEL G. NAMDRAH DNA BERT W. O'MALLEY
EMULOV XL. Hormone Action (Part E: Nuclear Structure and Function)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMORAH
EMULOV XLI. Carbohydrate Metabolism (Part B)
Edited by W. A. DOOW
EMULOV XLII. Carbohydrate Metabolism (Part C)
Edited by W. A. DOOW
EMULOV XLIII. Antibiotics
Edited by JOHN H. HSAH
EMULOV XLIV. Immobilized Enzymes
Edited by SUALK HCABSOM
EMULOV XLV. Proteolytic Enzymes (Part B)
Edited by OLZSAL DNAROL
EMULOV XLVI. Affinity Labeling
Edited by WILLIAM B. YBOKAJ DNA MEIR KEHCLlW
EMULOV XLVII. Enzyme Structure (Part E)
Edited by C. H. W. HIRS DNA EGRES N. FFEHSAMIT
EMULOV XLVIII. Enzyme Structure (Part F)
Edited by C. H. W. HIRS DNA EGRES N. FFEHSAMIT
EMULOV XLIX. Enzyme Structure (Part G)
Edited by C. H. W. HIRS DNA EGRES N. FFEHSAMIT
EMULOV L. Complex Carbohydrates (Part C)
Edited by ROTCIV GRUBSNIG
EMULOV LI. Purine and Pyrimidine Nucleotide Metabolism
Edited by AlCIRTAP A. HOFFEE DNA YRAM ELLEN SENOJ
EMULOV LII. Biomembranes (Part C: Biological Oxidations)
Edited by YENDIS REHCSIELF DNA RETSEL REKCAP
EMULOV LIII. Biomembranes (Part D: Biological Oxidations)
Edited by SIDNEY REHCSIELF DNA RETSEL REKCAP
EMULOV LIV. Biomembranes (Part E: Biological Oxidations)
Edited by YENDIS REHCSIELF DNA RETSEL REKCAP
°°,
XVlll METHODS IN ENZYMOLOGY
EMULOV LV. Biomembranes (Part F: Bioenergetics)
Edited yb SIDNEY REHCSIELF DNA RETSEL REKCAP
EMULOV LVI. Biomembranes (Part G: Bioenergetics)
Edited by SIDNEY REHCSIELF DNA RETSEL REKCAP
EMULOV LVII. Bioluminescence and Chemiluminescence
Edited yb ENELRAM A. DELUCA
EMULOV LVIII. Cell Culture
Edited by WILLIAM B. YBOKAJ DNA ARI NATSAP
EMULOV LIX. Nucleic Acids and Protein Synthesis (Part G)
Edited by KIVIE EVADLOM DNA ECNERWAL NAMSSORG
EMULOV LX. Nucleic Acids and Protein Synthesis (Part H)
Edited yb KIVlE EVADLOM DNA ECNERWAL NAMSSORG
EMULOV .16 Enzyme Structure (Part H)
Edited by C. H. W. HIRS DNA EGRES N. FFEHSAMIT
EMULOV 62. Vitamins and Coenzymes (Part D)
Edited by DLANOD B. McCoRMICK DNA LEUMEL D. THGIRW
EMULOV .36 Enzyme Kinetics and Mechanism (Part A: Initial Rate and Inhibi-
tor Methods)
Edited yb DANIEL L. HCIRUP
EMULOV 64. Enzyme Kinetics and Mechanism (Part B: Isotopic Probes and
Complex Enzyme Systems)
Edited by DANIEL L. HCIRUP
EMULOV 65. Nucleic Acids (Part I)
Edited yb ECNERWAL NAMSSORG DNA KIVIE EVADLOM
EMULOV .66 Vitamins and Coenzymes (Part E)
Edited by DLANOD B. McCoRMICK DNA LEUMEL D. THGIRW
EMULOV .76 Vitamins and Coenzymes (Part F)
Edited by DLANOD B. McCoRMICK DNA LEUMEL D. THGIRW
EMULOV 68. Recombinant DNA
Edited yb YAR Wu
EMULOV .96 Photosynthesis and Nitrogen Fixation (Part C)
Edited yb YNOHTNA NAS ORTEIP
EMULOV .07 Immunochemical Techniques (Part A)
Edited yb HELEN NAV SIKANUV DNA NHOJ J. ENOGNAL
EMULOV .17 Lipids (Part C)
Edited by JOHN M. NIETSNEWOL
EMULOV .27 Lipids (Part D)
Edited by JOHN M. NIETSNEWOL
EMULOV 73. Immunochemical Techniques (Part B)
Edited by JOHN J. ENOGNAL DNA HELEN NAV SIKANUV
METHODS IN ENZYMOLOGY xix
EMULOV 74. Immunochemical Techniques (Part C)
Edited yb JOHN J. LANGONE DNA HELEN NAV SIKANUV
EMULOV 75. Cumulative Subject Index Volumes XXXI, XXXII, XXXIV-LX
Edited yb EDWARD A. DENNIS DNA AHTRAM G. DENNIS
EMULOV 76. Hemoglobins
Edited yb ODLARE ANTONINI, LUIGI ,IDRANREB-ISSOR DNA EMILIA CHIAN-
ENOC
EMULOV 77. Detoxication and Drug Metabolism
Edited yb WILLIAM B. YBOKAJ
EMULOV 78. Interferons (Part A)
Edited yb SIDNEY AKTSEP
EMULOV 79. Intefferons (Part B)
Edited yb SIDNEY AKTSEP
EMULOV 80. Proteolytic Enzymes (Part C)
Edited yb OLZSAL DNAROL
EMULOV 81. Biomembranes (Part H: Visual Pigments and Purple Mem-
branes, I)
Edited yb LESTER REKCAP
EMULOV 82. Structural and Contractile Proteins (Part A: Extracellular Matrix)
Edited yb LEON W. MAHGNINNUC DNA DIXIE W. NESKIREDERF
EMULOV 83. Complex Carbohydrates (Part D)
Edited yb VICTOR GRUBSNIG
EMULOV 84. Immunochemical Techniques (Part D: Selected Immunoassays)
Edited yb JOHN J. LANGONE DNA HELEN NAV SIKANUV
EMULOV 85. Structural and Contractile Proteins (Part B: The Contractile Appa-
ratus and the Cytoskeleton)
Edited yb DIXIE W. NESKIREDERF DNA LEON W. MAHGNINNUC
EMULOV 86. Prostaglandins and Arachidonate Metabolites
Edited yb WILLIAM E. M. LANDS DNA WILLIAM L. SMITH
EMULOV 87. Enzyme Kinetics and Mechanism (Part C: Intermediates, Stereo-
chemistry, and Rate Studies)
Edited yb DANIEL L. PURICH
EMULOV 88. Biomembranes (Part I: Visual Pigments and Purple Mem-
branes, II)
Edited yb LESTER REKCAP
EMULOV 89. Carbohydrate Metabolism (Part D)
Edited yb WILLIS A. DOOW
EMULOV 90. Carbohydrate Metabolism (Part E)
Edited yb WILLIS A. DOOW
EMULOV 91. Enzyme Structure (Part I)
Edited yb C. H. W. HIRS DNA EGRES N. FFEHSAMIT
XX SDOHTEM NI YGOLOMYZNE
EMULOV 92. Immunochemical Techniques (Part E: Monoclonal Antibodies and
General Immunoassay Methods)
Edited by JOHN J. LANGONE DNA HELEN VAN VUNAKIS
EMULOV 93. Immunochemical Techniques (Part F: Conventional Antibodies,
Fc Receptors, and Cytotoxicity)
Edited by JOHN J. LANGONE DNA HELEN VAN VUNAKIS
EMULOV 94. Polyamines
Edited yb HERBERT TABOR DNA CELIA WHITE TABOR
EMULOV 95. Cumulative Subject Index Volumes 61-74, 76-80
Edited by EDWARD A. DENNIS DNA MARTHA G. DENNIS
EMULOV 96. Biomembranes Part J: Membrane Biogenesis: Assembly and
Targeting (General Methods; Eukaryotes)
Edited by SIDNEY FLEISCHER DNA BECCA FLEISCHER
EMULOV 97. Biomembranes Part K: Membrane Biogenesis: Assembly and
Targeting (Prokaryotes, Mitochondria, and Chloroplasts)
Edited by SIDNEY FLEISCHER DNA BECCA FLEISCHER
EMULOV 98. Biomembranes (Part L: Membrane Biogenesis: Processing and
Recycling)
Edited by SIDNEY FLEISCHER DNA BECCA FLEISCHER
EMULOV 99. Hormone Action (Part F: Protein Kinases)
Edited yb JACKIE D. CORBIN DNA JOEL G. HARDMAN
EMULOV 100. Recombinant DNA (Part B)
Edited yb RAY WU, LAWRENCE GROSSMAN, DNA KIVIE MOLDAVE
EMULOV 101. Recombinant DNA (Part C)
Edited by RAY Wu, LAWRENCE GROSSMAN, DNA KIVIE MOLDAVE
EMULOV 102. Hormone Action (Part G: Calmodulin and Calcium-Binding Pro-
teins)
Edited by ANTHONY R. MEANS DNA BERT W. O'MALLEY
EMULOV 103. Hormone Action (Part H: Neuroendocrine Peptides)
Edited by P. LEAHCIM NNOC
EMULOV 104. Enzyme Purification and Related Techniques (Part C)
Edited by WILLIAM B. YBOKAJ
EMULOV 105. Oxygen Radicals in Biological Systems
Edited by RETSUL REKCAP
EMULOV 106. Posttranslational Modifications (Part A)
Edited by FINN WOLD DNA KIVlE MOLDAVE
EMULOV 107. Posttranslational Modifications (Part B)
Edited by FINN WOLD DNA KIVIE MOLDAVE
EMULOV 108. Immunochemical Techniques (Part G: Separation and Character-
ization of Lymphoid Cells)
Edited by INNAVOIG DI SABATO, JOHN J. LANGONE, DNA
HELEN VAN VUNAKIS