Table Of Contentffirs.fm Page iii Monday, November 21, 2005 9:15 AM
Principles and Practice of
Clinical Bacteriology
Second Edition
Editors
Stephen H. Gillespie
Royal Free and University College Medical School, London, UK
and
Peter M. Hawkey
University of Birmingham, Birmingham, UK
ffirs.fm Page ii Monday, November 21, 2005 9:15 AM
ffirs.fm Page i Monday, November 21, 2005 9:15 AM
Principles and Practice of Clinical Bacteriology
Second Edition
ffirs.fm Page ii Monday, November 21, 2005 9:15 AM
ffirs.fm Page iii Monday, November 21, 2005 9:15 AM
Principles and Practice of
Clinical Bacteriology
Second Edition
Editors
Stephen H. Gillespie
Royal Free and University College Medical School, London, UK
and
Peter M. Hawkey
University of Birmingham, Birmingham, UK
ffirs.fm Page iv Monday, November 21, 2005 9:15 AM
Copyright © 2006 John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester,
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Library of Congress Cataloging in Publication Data
Principles and practice of clinical bacteriology/editors, Stephen H.
Gillespie and Peter M. Hawkey. — 2nd ed.
p. ; cm.
Includes bibliographical references and index.
ISBN-13: 978-0-470-84976-7 (cloth:alk. paper)
ISBN-10: 0-470-84976-2 (cloth:alk. paper)
1. Medical bacteriology.
[DNLM: 1. Bacteriological Techniques. QY 100 P957 2005] I. Gillespie, S. H.
II. Hawkey, P. M. (Peter M.)
QR46.P84 2005
616.9′041—dc22
2005013983
British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library
ISBN-13 978-0-470-84976-7 (cloth: alk. paper)
ISBN-10 0-470-84976-2 (cloth: alk. paper)
Typeset in 9/10pt Times by Integra Software Services Pvt. Ltd, Pondicherry, India
Printed and bound in Great Britain by Antony Rowe Ltd, Chippenham, Wiltshire
This book is printed on acid-free paper responsibly manufactured from sustainable forestry in which at least two trees are planted
for each one used for paper production.
ftoc.fm Page v Saturday, December 10, 2005 11:06 AM
Contents
List of Contributors vii 19 Brucella spp. 265
Preface ix Edward J. Young
20 Actinobacillus actinomycetemcomitans 273
Brian Henderson and Derren Ready
SECTION ONE GRAM-POSITIVE COCCI 1
21 Francisella tularensis 281
1 β-Haemolytic Streptococci 3
Petra C. F. Oyston
Androulla Efstratiou, Shiranee Sriskandan,
Theresa Lamagni and Adrian Whatmore 22 Rickettsia spp. 285
James G. Olson, Franca R. Jones
2 Oral and Other Non-β-Haemolytic Streptococci 21
and Patrick J. Blair
Roderick McNab and Theresa Lamagni
23 Bartonella spp. 295
3 Streptococcus pneumoniae 41
J. M. Rolain and D. Raoult
Indran Balakrishnan
24 Mycoplasma spp. 305
4 Enterococcus spp. 59
Christiane Bébéar, Sabine Pereyre and
Esteban C. Nannini and Barbara E. Murray
Cécile M. Bébéar
5 Staphylococcus aureus 73
25 Chlamydia spp. and Related Organisms 317
Sharon Peacock
S. J. Furrows and G. L. Ridgway
6 Coagulase-Negative Staphylococci 99
26 Tropheryma whipplei 329
Roger G. Finch
F. Fenollar and D. Raoult
SECTION TWO GRAM-POSITIVE BACILLI 113 27 Identification of Enterobacteriaceae 341
Peter M. Hawkey
7 Corynebacterium spp. 115
Aruni De Zoysa and Androulla Efstratiou 28 Escherichia coli and Shigella spp. 347
Christopher L. Baylis, Charles W. Penn,
8 Listeria and Erysipelothrix spp. 129
Nathan M. Thielman, Richard L. Guerrant,
Kevin G. Kerr
Claire Jenkins and Stephen H. Gillespie
9 Bacillus spp. and Related Genera 139
29 Salmonella spp. 367
Niall A. Logan and Marina Rodríguez-Díaz
Claire Jenkins and Stephen H. Gillespie
10 Mycobacterium tuberculosis 159
Stephen H. Gillespie 30 Klebsiella, Citrobacter,
Enterobacter and Serratia spp. 377
11 Non-Tuberculosis Mycobacteria 171 C. Anthony Hart
Stephen H. Gillespie
31 Donovanosis and Klebsiella spp. 387
12 Aerobic Actinomycetes 183 John Richens
Stephen H. Gillespie
32 Proteus, Providencia and Morganella spp. 391
SECTION THREE GRAM-NEGATIVE ORGANISMS 189 Peter M. Hawkey
13 Moraxella catarrhalis and Kingella kingae 191 33 Yersinia spp. 397
Alex van Belkum and Cees M. Verduin M. B. Prentice
14 Neisseria meningitidis 205 34 Vibrio spp. 407
Dlawer A. A. Ala’Aldeen and David P. J. Turner Tom Cheasty
15 Neisseria gonorrhoeae 221 35 Aeromonas and Plesiomonas spp. 419
Catherine A. Ison Alpana Bose
16 Acinetobacter spp. 231 36 Pseudomonas and Burkholderia spp. 427
Peter Hawkey and Eugenie Bergogne-Berezin Tyrone L. Pitt and Andrew J. H. Simpson
17 Haemophilus spp. 245 37 Legionella spp. 445
Derrick W. Crook and Derek W. Hood T. G. Harrison
18 Bordetella spp. 253 38 Coxiella burnetii 457
Qiushui He, Jussi Mertsola and James G. Olson, Franca R. Jones and
Matti K. Viljanen Patrick J. Blair
ftoc.fm Page vi Saturday, December 10, 2005 11:06 AM
vi CONTENTS
SECTION FOUR SPIRAL BACTERIA 461 SECTION FIVE OBLIGATE ANAEROBIC BACTERIA 527
39 Leptospira spp. 463 44 Anaerobic Cocci 529
P. N. Levett D. A. Murdoch
45 Non-Sporing Gram-Negative Anaerobes 541
40 Helicobacter spp. and Related
Sheila Patrick and Brian I. Duerden
Organisms 473
Peter J. Jenks 46 Clostridium difficile 557
Mark H. Wilcox
41 Campylobacter and Arcobacter spp. 485
Diane E. Taylor and Monika Keelan 47 Other Clostridium spp. 567
Ian R. Poxton
42 Treponemes 503
Andrew J. L. Turner 48 Anaerobic Actinomycetes and Related Organisms 575
Val Hall
43 Borrelia spp. 511
Sudha Pabbatireddy and
Benjamin J. Luft Index 587
fbetw.fm Page vii Monday, November 14, 2005 3:27 PM
List of Contributors
Dlawer A. A. Ala’Aldeen Molecular Bacteriology and Immunology Richard L. Guerrant Division of Infectious Diseases, University
Group, Division of Microbiology, University Hospital, Nottingham of Virginia School of Medicine, Charlottesville, VA 22908, USA
NG7 2UH, UK
Val Hall Anaerobe Reference Laboratory, National Public Health
Indran Balakrishnan Department of Medical Microbiology, Royal Service for Wales, Microbiology Cardiff, University Hospital of
Free Hospital, Pond Street, London NW3 2QG, UK Wales, Heath Park, Cardiff CF4 4XW, UK
Christopher L. Baylis Campden & Chorleywood Food Research T. G. Harrison Respiratory and Systemic Infection Laboratory,
Association (CCFRA), Chipping Campden, Gloucestershire GL55 Health Protection Agency, Centre for Infection, 61 Colindale
6LD, UK Avenue, London NW9 5HT, UK
Cécile M. Bébéar Laboratoire de Bactériologie, Université Victor C. Anthony Hart Medical Microbiology Department, Royal
Segalen Bordeaux 2, 146 rue Léo Saignat, 33076 Bordeaux, France Liverpool Hospital, Duncan Building, Daulby Street, Liverpool
L69 3GA, UK
Christiane Bébéar Laboratoire de Bactériologie, Université Victor
Segalen Bordeaux 2, 146 rue Léo Saignat, 33076 Bordeaux, France Peter M. Hawkey Division of Immunity and Infection, The
Medical School, Edgbaston, Birmingham B15 2TT, UK
Alex van Belkum Department of Medical Microbiology & Infectious
Diseases, Erasmus University Medical Center Rotterdam EMCR, Qiushui He Pertussis Reference Laboratory, National Public Health
Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands Institute, Kiinamyllynkatu 13, 20520 Turku, Finland
Eugenie Bergogne-Berezin University Paris 7, Faculty of Medicine Brian Henderson Division of Infection and Immunity, Eastman
Bichat, 100 bis rue du Cherche-Midi, Paris 75006, France Dental Institute, 256 Gray’s Inn Road, London WC1X 8LD, UK
Patrick J. Blair US Embassy Jakarta, US NAMRU 2, FPO AP Derek W. Hood Molecular Infectious Diseases, Department of
96520-8132 Paediatrics, Weatherall Institute of Molecular Medicine, John
Radcliffe Hospital, Headington, Oxford OX3 9DS, UK
Alpana Bose Centre for Medical Microbiology, Royal Free and
University College Medical School, Hampstead Campus, Rowland Catherine Ison Sexually Transmitted Bacteria Reference Laboratory,
Hill Street, London NW3 2PF, UK Centre for Infection, Health Protection Agency, 61 Colindale
Avenue, London NW9 5HT, UK
Tom Cheasty HPA Colindale, Laboratory of Enteric Pathogens,
Centre for Infection, 61 Colindale Avenue, London NW9 5HT, UK Claire Jenkins Department of Medical Microbiology, Royal
Free Hospital NHS Trust, Rowland Hill Street, London NW3
Derrick W. Crook Department of Clinical Microbiology, John
2PF, UK
Radcliffe Hospital, Level 7, Headington, Oxford OX3 9DU, UK
Peter J. Jenks Department of Microbiology, Plymouth Hospitals
Aruni De Zoysa Health Protection Agency, Centre for Infection,
NHS Trust, Derriford Hospital, Plymouth PL6 8DH, UK
Department of Respiratory and Systemic Infections, 61 Colindale
Avenue, London NW9 5HT, UK Franca R. Jones National Naval Medical Center, Microbiology
Laboratory, 8901 Wisconsin Avenue, Bethesda, MD 20889, USA
Brian I. Duerden Anaerobe Reference Laboratory, Department of
Medical Microbiology, University of Wales College of Medicine, Monika Keelan Department of Laboratory Medicine & Pathology,
Heath Park, Cardiff CF14 4XN, UK Division of Medical Laboratory Science, B-117 Clinical Sciences
Building, University of Alberta, Edmonton, Alberta, Canada
Androulla Efstratiou Respiratory and Systemic Infection Laboratory,
T6G 2G3
Health Protection Agency, Centre for Infection, 61 Colindale
Avenue, London NW9 5HT, UK Kevin G. Kerr Department of Microbiology, Harrogate District
Hospital, Lancaster Park Road, Harrogate HG2 7SX, UK
Florence Fenollar Unité des Rickettsies, CNRS UMR 6020A,
Faculté de Médecine, Université de la Méditerranée, 27 Bd Jean Theresa Lamagni Healthcare Associated Infection & Antimicrobial
Moulin, 13385 Marseille Cedex 05, France Resistance Department, Health Protection Agency, Centre for
Infection, 61 Colindale Avenue, London NW9 5EQ, UK
Roger G. Finch Department of Microbiology and Infectious
Diseases, The Nottingham City Hospital NHS Trust, The Clinical Paul N. Levett Provincial Laboratory, Saskatchewan Health, 3211
Sciences Building, Hucknall Road, Nottingham NG5 1PB, UK Albert Street, Regina, Saskatchewan, Canada S4S 5W6
Sarah J. Furrows Department of Clinical Parasitology, The Hospital Niall A. Logan Department of Biological and Biomedical Sciences,
of Tropical Diseases, Mortimer Market off Tottenham Court Road, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4
London WC1E 6AU, UK 0BA, UK
Stephen H. Gillespie Centre for Medical Microbiology, Royal Free Benjamin J. Luft Department of Medicine, Division of
and University College Medical School, Hampstead Campus, Infectious Diseases, SUNY at Stony Brook, New York, NY
Rowland Hill Street, London NW3 2PF, UK 11794-8160, USA
