Preservation of human oocytes : from crybiology science to clinical applications

324 Pages·2009·4.645 MB·xxii, 299 p. : ill\324

by  Andrea Borini, Giovanni Coticchio

Reproductive Medicine Borini PreservAtion
•
Coticchio
About the book
of HumAn
Oocyte cryopreservation entails important potential advantages for human
IVF, offering a less ethically disputable alternative to embryo cryopreservation,
simplifying and making safer oocyte donation, and giving an opportunity for
fertility preservation to women at risk of premature ovarian failure as an effect
oocytes
of genetic factors or chemo- or radiotherapies. Oocyte cryopreservation could
also meet the expectations of women wishing to preserve their fertility for
social reasons. In the last few years, advances in cryopreservation
methodologies have dramatically improved the efficiency of oocyte
cryopreservation, leading to the birth of over a thousand babies and
o
challenging the supremacy of embryo cryopreservation as the preferred
from cryobiology science
form of fertility preservation. f

This text has been conceived with the aim of offering a comprehensive HP
view of the state of the art of oocyte cryopreservation. It covers fundamental ur to Clinical Applications
concepts of low temperature storage (controlled rate slow cooling and e
m
vitrification), aspects of oocyte physiology relevant to the process of s
cryopreservation, essential biological and clinical evidence, and ethical Ae
implications of oocyte cryopreservation, thereby providing a complete
r
overview of progress in this strategy in assisted reproduction. n
v

About the editors oA
t
o
ANDREA BORINI (MD) and GIOVANNI COTICCHIO (BSc, MMedSci, PhD) are, i
respectively, the Clinical and Scientific Director and Scientific Supervisor co
of the IVF Laboratory of Tecnobios Procreazione, Bologna, Italy. yn
t

e
The immunofluorescence image on the front cover originates from a collaborative work between
s
Tecnobios Procreazione and Professor David Albertini
Y004251
Edited by
Andrea Borini
Giovanni Coticchio
Preservation
of Human Oocytes
Reproductive Medicine and Assisted Reproductive Techniques Series
Series editors
David Gardner,
University of Melbourne,
Australia
Jan Gerris,
University Hospital Ghent,
Belgium
Zeev Shoham,
Kaplan Hospital,
Rehovot, Israel
Titles
1. Jan Gerris, Annick Delvigne, François Olivennes
Ovarian Hyperstimulation Syndrome, ISBN: 9781842143285
2. Alastair G Sutcliffe
Health and Welfare of ART Children, ISBN 9780415379304
3. Seang Lin Tan, Ri-Chen Chian, William Buckett
In-vitro Maturation of Human Oocytes, ISBN: 9781842143322
4. Christoph Keck, Clemens Tempfer, Jen-Noel Hugues
Conservative Infertility Management, ISBN: 9780415384513
5. Carlos Simon, Antonio Pellicer
Stem Cells in Human Reproduction, ISBN: 9780415397773
6. Kay Elder, Jacques Cohen
Human Preimplantation Embryo Selection, ISBN: 9780415399739
7. Michael Tucker, Juergen Liebermann
Vitrifi cation in Assisted Reproduction, ISBN: 9780415408820
8. John D Aplin, Asgerally T Fazleabas, Stanley R Glasser, Linda C Giudice
The Endometrium, Second Edition, ISBN: 9780415385831
9. Adam H Balen
Infertility in Practice, Third Edition, ISBN: 9780415450676
10. Nick Macklon, Ian Greer, Eric Steegers
Textbook of Periconceptional Medicine, ISBN: 9780415458924
11. Carlos Simon, Antonio Pellicer
Stem Cells in Human Reproduction, Second Edition, ISBN:
9780415471718
12. Andrea Borini, Giovanni Coticchio
Preservation of Human Oocytes, ISBN 9780415476799
Preservation
of Human Oocytes
Edited by
Andrea Borini and Giovanni Coticchio
Tecnobios Procreazione
Centre for Reproductive Health
Bologna, Italy
© 2009 Informa UK Ltd
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ISBN-10: 0 415 47679 8
ISBN-13: 978 0 415 47679 9
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Contents
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . x
Color Plates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi
PART 1: FUNDAMENTAL CRYOBIOLOGY
1. A Historical Overview of Embryo and Oocyte Preservation in the World
of Mammalian In Vitro Fertilization and Biotechnology . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Nucharin Songsasen and Pierre Comizzoli
2. Principles of Cryopreservation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
David E. Pegg
3. The Rational Basis for Controlled Rate Slow Cooling . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Barry Fuller and Sharon Paynter
4. Fundamentals and Current Practice of Vitrifi cation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
Lilia L. Kuleshova
5. Predictive Models for the Development of Improved Cryopreservation
Protocols for Human Oocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62
John McGrath
PART 2: BIOLOGICAL ASPECTS OF OOCYTE CRYOPRESERVATION
6. The Natural Life Cycle of the Mammalian Oocyte . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83
David F. Albertini and S. Darlene Limback
7. Essential features of the mature oocyte . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95
Ursula Eichenlaub-Ritter
8. Expression of Functional Aquaporins in Oocytes and Embryos
and the Impact on Cryopreservation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104
François Chauvigné and Joan Cerdà
9. Oocyte Storage at Different Developmental Stages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116
Mafalda Rato and Carlos E. Plancha
10. Oocyte Cryopreservation in the Mouse . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128
Maureen J. Wood
11. Oocyte Storage in Domestic Species . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142
Gábor Vajta, Jason Conceicao, and John Yovich
12. Control of the Solution Effect During Controlled-Rate Cooling:
Principles and Practical Application . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151
James J. Stachecki
13. Cryopreservation and the Cytoskeleton of the Human Oocyte . . . . . . . . . . . . . . . . . . . 162
Giovanni Coticchio and Maria Antonietta Bonu
CONTENTS vi
14. Non-invasive Assessment of Cryopreserved Oocytes Through
Polarized Light Microscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 174
Markus Montag, Maria Köster, Benjamin Rösing, Katrin van der Ven, Hans van der Ven
15. Impact of Cryopreservation on Oocyte Physiology,
Metabolism and the Proteome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184
Mark G. Larman and David K. Gardner
PART 3: LABORATORY, CLINICAL, AND ETHICAL ASPECTS
OF OOCYTE STORAGE
16. Quality Management of a Low Temperature Storage Program
in the Human IVF Laboratory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198
Lucia De Santis
17. The Contribution of Embryo Cryopreservation to the Clinical Effi cacy
of ART and to a Reduction of ART Multiple Pregnancies . . . . . . . . . . . . . . . . . . . . . . . 205
Karl G. Nygren
18. Factors Infl uencing the Clinical Effi ciency of Oocyte Cryopreservation . . . . . . . . . . . 209
Debra A. Gook and David H. Edgar
19. The Early and Recent History of Oocyte Cryopreservation in Human IVF . . . . . . . . . 221
Eleonora Porcu, Leonardo Notarangelo, Antonia Bazzocchi, Chiara Landolfo,
and Stefano Venturoli
20. Success Rates from Oocyte Cryopreservation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235
Andrea Borini and Maria Antonietta Bonu
21. Clinical Evidence of Oocyte Vitrifi cation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246
Ri-Cheng Chian and Yin-Xia Cao
22. Oocyte Storage for Fertility Preservation Before Radio- and Chemotherapy . . . . . . . 256
Michael von Wolff
23. The Impact of Oocyte Storage in Oocyte Donation Treatments . . . . . . . . . . . . . . . . . . . 268
Ana Cobo and José Remohí
24. The Health of Children from Cryopreserved Oocytes and Embryos . . . . . . . . . . . . . . 278
Audrey Soo and Alastair Sutcliffe
25. The Ethics of Fertility Preservation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290
Carlo Flamigni
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296
Contributors
David F. Albertini PhD Departments of Molecular and Integrative Physiology, Anatomy and
Cell Biology, Obstetrics and Gynecology, and Center for Reproductive Sciences, Kansas
University Medical Center, Kansas City, Kansas, U.S.A.
Antonia Bazzocchi MD Reproductive Medicine Unit, Infertility and IVF Center, University of
Bologna, Bologna, Italy
Maria Antonietta Bonu BSC Tecnobios Procreazione, Centre for Reproductive Health,
Bologna, Italy
Andrea Borini MD Tecnobios Procreazione, Centre for Reproductive Health, Bologna, Italy
Yun-Xia Cao MD Center for Reproductive Medicine, Department of Obstetrics and
Gynecology, The First Affi liated Hospital of Anhui Medical University, Hefei, P.R. China
Joan Cerdà PhD Laboratory of the Institut de Recerca i Tecnologia Agroalimentàries (IRTA)-
Institut de Ciències del Mar, Consejo Superior de Investigaciones Científi cas (CSIC),
Barcelona, Spain
François Chauvigné PhD Laboratory of the Institut de Recerca i Tecnologia Agroalimentàries
(IRTA)-Institut de Ciències del Mar, Consejo Superior de Investigaciones Científi cas (CSIC),
Barcelona, Spain
Ri-Cheng Chian PhD Department of Obstetrics and Gynecology, McGill University, Montreal,
Canada
Ana Cobo PhD Cryobiology Unit, IVI-Valencia, Valencia, Spain
Pierre Comizzoli PhD Department of Reproductive Sciences, Center for Species Survival,
Smithsonian’s National Zoological Park, Washington D.C., U.S.A.
Jason Conceicao PhD PIVET Medical Centre, Perth, Western Australia, Australia
Giovanni Coticchio PhD Tecnobios Procreazione, Centre for Reproductive Health,
Bologna, Italy
Lucia De Santis BSC IVF Unit, Department of Obstetrics and Gynaecology, University
Vita-Salute, H. S. Raffaele, Milan, Italy
David H. Edgar PhD Reproductive Services, Royal Women’s Hospital/Melbourne IVF and
Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Victoria,
Australia
Ursula Eichenlaub-Ritter PhD Department of Gene Technology and Microbiology, Faculty of
Biology, University of Bielefeld, Bielefeld, Germany
Carlo Flamigni MD National Council of Bioethics, Rome, Italy
Barry Fuller PhD Division of Surgery and Interventional Sciences, UCL Medical School, Royal
Free Hospital Campus, London, U.K.
David K. Gardner Dphil Department of Zoology, The University of Melbourne, Melbourne,
Victoria, Australia
CONTRIBUTORS viii
Debra A. Gook PhD Reproductive Services, Royal Women’s Hospital/Melbourne IVF and
Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Victoria,
Australia
Maria Köster DVM Department of Gynecological Endocrinology & Reproductive Medicine,
University of Bonn, Bonn, Germany
Lilia L. Kuleshova PhD Low Temperature Preservation Unit, National University Medical
Institutes, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Chiara Landolfo MD Reproductive Medicine Unit, Infertility and IVF Center, University of
Bologna, Bologna, Italy
Mark G. Larman PhD Department of Zoology, The University of Melbourne, Melbourne,
Victoria, Australia
S. Darlene Limback MSC Departments of Molecular and Integrative Physiology, Anatomy
and Cell Biology, Obstetrics and Gynecology, and Center for Reproductive Sciences,
Kansas University Medical Center, Kansas City, Kansas, U.S.A.
John McGrath PhD Department of Aerospace and Mechanical Engineering,
University of Arizona, Tucson, Arizona, U.S.A.
Markus Montag PhD Department of Gynecological Endocrinology & Reproductive Medicine,
University of Bonn, Bonn, Germany
Leonardo Notarangelo BSC Reproductive Medicine Unit, Infertility and IVF Center,
University of Bologna, Bologna, Italy
Karl G. Nygren MD PhD Queen Sophia Hospital, Stockholm, Sweden
Sharon Paynter PhD Department of Obstetrics and Gynaecology, Cardiff University,
Heath Park, Cardiff, U.K.
David E. Pegg PhD Department of Biology, University of York, York, U.K.
Carlos E. Plancha PhD Biology of Reproduction Unit, Institute of Histology and
Developmental Biology, Faculty of Medicine of Lisbon, Lisboa, Portugal and Centro Médico
de Assistência à Reprodução (CEMEARE), Lisboa, Portugal
Eleonora Porcu MD Reproductive Medicine Unit, Infertility and IVF Center,
University of Bologna, Bologna, Italy
Mafalda Rato MSC Centro Médico de Assistência à Reprodução (CEMEARE),
Lisboa, Portugal
José Remohí MD PhD Obstetrics and Gynaecology, Faculty of Medicine,
University of Valencia, IVI-Valencia, Valencia, Spain
Benjamin Rösing MD Department of Gynecological Endocrinology & Reproductive
Medicine, University of Bonn, Bonn, Germany
Nucharin Songsasen DVM, PhD Department of Reproductive Sciences, Center for Species
Survival, Smithsonian’s National Zoological Park, Front Royal, Virginia, U.S.A.
Audrey Soo BSC General and Adolescent Unit, Institute of Child Health, University College,
London, London, U.K.
James J. Stachecki PhD Tyho-Galileo Research Laboratories, Livingston, New Jersy, U.S.A.
Alastair Sutcliffe MD PhD General and Adolescent Unit, Institute of Child Health,
University College, London, U.K.
Gabor Vajta PhD PIVET Medical Centre, Perth, Western Australia, Australia and Cairns
Fertility Centre, Cairns, Queensland, Australia
ix CONTRIBUTORS
Hans van der Ven MD Department of Gynecological Endocrinology & Reproductive
Medicine, University of Bonn, Bonn, Germany
Katrin van der Ven MD Department of Gynecological Endocrinology & Reproductive
Medicine, University of Bonn, Bonn, Germany
Stefano Venturoli MD Reproductive Medicine Unit, Infertility and IVF Center,
University of Bologna, Bologna, Italy
Michael von Wolff MD Department of Gynecological Endocrinology and Reproductive
Medicine, Women’s Hospital, University of Bern, Bern, Switzerland
Maureen J. Wood MD Department of Obstetrics and Gynaecology, University of Aberdeen,
Maternity Hospital, Foresterhill, Aberdeen, U.K.
John Yovich MD PIVET Medical Centre, Perth, Western Australia, Australia and Cairns
Fertility Centre, Cairns, Queensland, Australia