Table Of ContentPharmaceuticals
Nutraceuticals
to
A Shift in
Disease Prevention
Pharmaceuticals
Nutraceuticals
to
A Shift in
Disease Prevention
Dilip Ghosh
R. B. Smarta
CRC Press
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Library of Congress Cataloging‑in‑Publication Data
Names: Ghosh, Dilip K., author. | Smarta, R. B., 1944- author.
Title: Pharmaceuticals to nutraceuticals : a shift in disease prevention /
Dilip Ghosh and R. B. Smarta.
Description: Boca Raton : Taylor & Francis/CRC Press, 2017. | Includes
bibliographical references and index.
Identifiers: LCCN 2016015578 | ISBN 9781482260755 (hardback : alk. paper)
Subjects: | MESH: Dietary Supplements--standards | Functional Food--standards
| Pharmaceutical Preparations | Holistic Health
Classification: LCC RM301 | NLM QU 145.5 | DDC 615.1--dc23
LC record available at https://lccn.loc.gov/2016015578
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Contents
Authors ......................................................................................................................ix
Contributor ................................................................................................................xi
Introduction ............................................................................................................xiii
Section i introduction
Chapter 1 Redefining Nutraceutical and Functioning Foods as Part of a
Journey from Pharma to Nutra .............................................................3
R. B. Smarta
Chapter 2 Holistic Health through Nutrition, Diet, and Nutraceuticals for
Prevention and Treatment ...................................................................17
R. B. Smarta
Chapter 3 A Paradigm Shift from Cure to Prevention and Treatment ...............25
R. B. Smarta
Chapter 4 Traditional and Modern Medicine: Filling the Gap ...........................35
Dilip Ghosh
Section ii Quality–Safety–efficacy: three Mantras
Chapter 5 Drug–Nutrient Interactions: Their Role in Clinical Outcomes ..........51
Dilip Ghosh
Chapter 6 Existing and Innovative Models of Health and Disease:
Elaborating on Foods versus Drugs ...................................................61
R. B. Smarta
v
vi Contents
Section iii Marketing and Product Positioning
Chapter 7 Market Dynamics and Evolution in Nutraceuticals ...........................73
R. B. Smarta
Chapter 8 Business Perspective ..........................................................................87
R. B. Smarta
Chapter 9 Science to Business Viability .............................................................97
R. B. Smarta
Section iV Regulatory Perspective
Chapter 10 The Role of Nanoparticles in Both Nutraceutical and
Pharmaceutical Products ..................................................................109
Dilip Ghosh
Chapter 11 A Regulatory Perspective of Nutraceuticals and
Phytomedicines in India ...................................................................121
R. B. Smarta
Section V Underpinning Science
Chapter 12 Vitamin E in Health and Wellness: What Would Be the Ideal
Therapeutic Dosage? ........................................................................133
Dilip Ghosh and Rohit Ghosh
Chapter 13 Clinical Applications of Metabolites and Metabolomics .................161
Dilip Ghosh
Contents vii
Section Vi new Journeys through categorization
Chapter 14 Medical Foods: A New Domain in the Food–Drug Interphase .......173
Dilip Ghosh
Chapter 15 Probiotics: From Bench to Market ...................................................183
Dilip Ghosh
Chapter 16 The Combination of Foods and Drugs: Advantages and
Drawbacks ........................................................................................193
R. B. Smarta
Section Vii Future trends
Chapter 17 The Role of Food Bioactives in Disease Prevention ........................205
R. B. Smarta
Chapter 18 The Journey from Personalized Medicine to Personalized
Nutrition ...........................................................................................223
Dilip Ghosh
Chapter 19 Quality Controversies in Phytopharmaceuticals ..............................247
Dilip Ghosh
Index ......................................................................................................................259
Authors
Dilip Ghosh, PhD, is an international speaker, facilitator, and author. He is pro-
fessionally associated with Soho Flordis International (SFI) and Western Sydney
University, and is an Honorary Ambassador with the Global Harmonization Initiative
(GHI), all in Australia.
With more than 20 years of experience in both the pharmaceutical and food and
nutrition industries, he is one of the pioneer researchers to assess the health claim
opportunities of potential functional food ingredients and complementary medicines
through an evaluation of the current scientific evidence–based and related claims,
providing commentaries on the gaps in science, including potential requirements for
research, such as human studies.
Dr. Ghosh received a PhD in biomedical science from the University of Calcutta,
India, along with a BSc (Hons) and MSc in zoology/microbiology and an MPhil in
environmental sciences.
Dr. Ghosh has published more than 60 papers in peer-reviewed journals and
numerous articles in food and nutrition magazines and books. His recent books,
Biotechnology in Functional Foods and Nutraceuticals, Innovation of Healthy and
Functional Foods, and Clinical Aspects of Functional Foods and Nutraceuticals,
were all published by CRC Press/Taylor & Francis in 2010, 2012, and 2014, respec-
tively. He is the review editor of Frontiers in Nutrigenomics (2011–present), the
American Journal of Advanced Food Science and Technology (2012–present),
the Journal of Obesity and Metabolic Research (2013–present), and the Journal
of Bioethics (2013–present). He was an associate editor and member of Toxicology
Mechanisms and Methods, Taylor & Francis (2006–2007), and is a columnist for the
World of Nutraceuticals. Dr. Ghosh is also in executive member and advisor of the
Health Foods and Dietary Supplements Association (HADSA).
R. B. Smarta, PhD, has designed management agendas for profitable growth and
relevant expansion, launching new concepts, ideas, and projects for national and
global clients in pharmaceuticals, nutraceuticals, and wellness. Dr. Smarta has been
in the industry for more than four decades and in consulting for a little more than
three decades.
He is the founder and managing director of Interlink Marketing Consultancy Pvt.
Ltd. In addition to a postgraduate degree in organic chemistry, Dr. Smarta earned an
MMS in marketing from the University of Mumbai. He holds a doctorate (PhD) in
management from the University of East Georgia, is a Fellow of the Royal Society
of Arts and Commerce (FRSA), and is a Certified Management Consultant (CMC).
He has added value and created an impact on the performance of a wide variety of
clients at national and multinational corporations.
As an advocate of this nascent and essential industry of nutrition and nutraceuti-
cals, Dr. Smarta is assisting in shaping the industry and its agenda with the help of
industry leaders, members, and regulatory bodies through India’s Health Foods and
Dietary Supplements Association as an Honorary Secretary.
ix
x Authors
Dr. Smarta has penned eight books in the areas of pharma marketing and pharma-
ceutical business and nutraceuticals. Some of his titles have also been translated into
German. He regularly contributes articles to several dailies and industry periodicals.
He has produced video-based training packages called Interact for corporate train-
ers to enhance their skills on an ongoing basis. Dr. Smarta is a recipient of many
national awards.
