Phagocyte-pathogen interactions : macrophages and the host response to infection

586 Pages·2009·10.131 MB·English

by  David G Russell, Siamon Gordon

Phagocyte-Pathogen
Interactions
Macrophages and the Host Response
to Infection
This page intentionally left blank
Phagocyte-Pathogen
Interactions
Macrophages and the Host Response
to Infection
Edited by
David G. Russell
College of Veterinary Medicine, Cornell University, Ithaca, New York
Siamon Gordon
Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
Washington, D.C.
Cover:Leishmaniamexicanainmacrophages(courtesyDavidRussell)
Copyright(cid:2)2009ASMPress
AmericanSocietyforMicrobiology
1752NStreet,N.W.
Washington,DC20036-2904
LibraryofCongressCataloging-in-PublicationData
Phagocyte-pathogeninteractions:macrophagesandthehostresponsetoinfection / editedbyDavidG.
Russell,SiamonGordon.
p.;cm.
Includesbibliographicalreferencesandindex.
ISBN978-1-55581-401-4
1. Phagocytes. 2. Macrophages. 3. Host-parasiterelationships. I. Russell,DavidG.,1956–
II. Gordon,Siamon. III. AmericanSocietyforMicrobiology.
[DNLM:1.Phagocytes—pathology. 2. Host-PathogenInteractions—immunology. 3. Macrophages—
immunology. QW690P53172009]
QR185.8.P45P4732009
616.07’99—dc22
2009016479
AllRightsReserved
PrintedintheUnitedStatesofAmerica
10987654321
Addresseditorialcorrespondenceto:ASMPress,1752NSt.,N.W.,Washington,DC
20036-2904,U.S.A.
Sendordersto:ASMPress,P.O.Box605,Herndon,VA20172,U.S.A.
Phone:[phone]
Fax:[phone]
Email:[email protected]
Online:estore.asm.org
Contents
Contributors / vii 7 C-Type Lectins: Multifaceted Receptors in
Foreword: What Would Darwin Have Said? / xi Phagocyte Biology / 123
Samuel C. Silverstein ALESSANDRA CAMBI AND CARL G. FIGDOR
Preface / xiii
8 Integrins on Phagocytes / 137
WOUTER L. W. HAZENBOS AND ERIC J. BROWN
SECTION I
BIOLOGY OF THE PROFESSIONAL 9 Intracytosolic Sensing of Pathogens:
PHAGOCYTE / 1 Nucleic Acid Receptors, NLRs, and the
Associated Responses during Infections and
1 Neutrophils Forever... / 3 Autoinflammatory Diseases / 153
TACO W. KUIJPERS, TIMO K. VAN DEN BERG, AND THOMAS HENRY AND DENISE M. MONACK
DIRK ROOS
10 Phagocytes Are a Source of the Fluid-
2 Macrophages: Microbial Recognition and Phase Pattern Recognition Receptor PTX3:
Response / 27 Interplay between Cellular and Humoral
ANNETTE PLU¨DDEMANN AND SIAMON GORDON Innate Immunity / 171
ALBERTO MANTOVANI, BARBARA BOTTAZZI,
3 Dendritic Cells and Their Tissue ANDREA DONI, GIOVANNI SALVATORI,
PASCALE JEANNIN, AND CECILIA GARLANDA
Microenvironment during Exposure to
Pathogens / 51
11 Leukocyte Chemotaxis / 183
A. MORTELLARO, F. GRANUCCI, M. FOTI, AND
ANN P. WHEELER AND ANNE J. RIDLEY
P. RICCIARDI-CASTAGNOLI
SECTION III
SECTION II PHAGOCYTOSIS: SIGNALING,
MEMBRANE RECEPTORS: RECOGNITION, CYTOSKELETON, AND THE
ADHESION, PHAGOCYTOSIS, CHEMOTAXIS, PHAGOSOME / 193
AND MIGRATION / 69
12 Signaling for Phagocytosis / 195
JOEL A. SWANSON
4 Fc Receptors and Phagocytosis / 71
STEVEN GREENBERG AND BENJAMIN M. DALE
13 Membrane Trafficking during Phagosome
Formation and Maturation / 209
5 Chemokines and Phagocyte
GREGORY D. FAIRN, ELENA GERSHENZON, AND
Trafficking / 93
SERGIO GRINSTEIN
TIMOTHY J. WILLIAMS AND SARA M. RANKIN
14 Acidification of Endosomes and
6 Toll-Like Receptors / 107 Phagosomes / 225
RICARDO T. GAZZINELLI, KATE FITZGERALD, AND SUSHMITA MUKHERJEE AND
DOUGLAS T. GOLENBOCK FREDERICK R. MAXFIELD
v
vi ■ CONTENTS
15 Actin-Based Motility in Professional 25 The Role of Phagocytic Cells during
Phagocytes / 235 Shigella Invasion of the Colonic
FREDERICK S. SOUTHWICK Mucosa / 405
GUY TRAN VAN NHIEU AND
16 Functional Analysis of the PHILIPPE SANSONETTI
Intraphagosomal Environment of the
26 Autophagy: a Fundamental Cytoplasmic
Macrophage: Fluorogenic Reporters and the
Sanitation Process Operational in All Cell
Transcriptional Responses of Salmonella and
Types Including Macrophages / 419
Mycobacterium spp. / 249
VOJO DERETIC
ROBIN M. YATES, KYLE H. ROHDE,
ROBERT B. ABRAMOVITCH, AND
27 Brucella, a Perfect Trojan Horse in
DAVID G. RUSSELL
Phagocytes / 427
SUZANA P. SALCEDO AND JEAN-PIERRE GORVEL
SECTION IV 28 Interaction of Candida albicans with
BRIDGING THE GAP BETWEEN THE INNATE Phagocytes / 437
ˆ
AND ACQUIRED IMMUNE RESPONSE / 265 INES FARO-TRINDADE AND GORDON D. BROWN
17 Novel Anti-Inflammatory and 29 The Parasite Point of View: Insights and
Questions on the Cell Biology of Trypanosoma
Proresolution Lipid Mediators in Induction
and Leishmania Parasite-Phagocyte
and Modulation of Phagocyte Function / 267
Interactions / 453
CHARLES N. SERHAN AND JULIO ALIBERTI
KEITH GULL
18 Cytokines and Macrophages and
30 Phagocyte Interactions with the
Dendritic Cells: Key Modulators of Immune
Intracellular Protozoan Toxoplasma
Responses / 281
gondii / 463
FRANK KAISER AND ANNE O’GARRA
ERIC Y. DENKERS
19 Macrophage Classical Activation / 301
31 Macrophages in Helminth Infection:
DONALD C. VINH AND STEVEN M. HOLLAND
Effectors, Regulators, and Wound
Healers / 477
20 The Functional Heterogeneity of
JUDITH E. ALLEN AND THOMAS A. WYNN
Activated Macrophages / 325
XIA ZHANG AND DAVID M. MOSSER
SECTION VI
MODELS OF HOST-PATHOGEN
21 Recognition and Removal of Apoptotic
INTERACTIONS / 491
Cells / 341
PETER M. HENSON AND DONNA L. BRATTON
32 Dictyostelium discoideum: a Model
Phagocyte and a Model for Host-Pathogen
22 Regulation and Antimicrobial Function of
Interactions / 493
Inducible Nitric Oxide Synthase in
ZHIRU LI AND RALPH R. ISBERG
Phagocytes / 367
CHRISTIAN BOGDAN 33 Phagocytosis in Drosophila melanogaster
Immune Response / 513
VINCENT LECLERC, ISABELLE CALDELARI,
NATALIA VERESHCHAGHINA, AND
SECTION V
JEAN-MARC REICHHART
PATHOGENS OF THE PROFESSIONAL
PHAGOCYTE / 379
34 The Zebrafish as a Model of
Host-Pathogen Interactions / 523
23 The Multiple Interactions between
J. MUSE DAVIS AND LALITA RAMAKRISHNAN
Salmonella and Phagocytes / 381
JESSICA A. THOMPSON AND DAVID W. HOLDEN 35 Whole Genome Screens in
Macrophages / 537
24 Legionella pneumophila, a Pathogen of BABAK JAVID AND ERIC J. RUBIN
Amoebae and Macrophages / 393
MICHELE S. SWANSON AND ANDREW BRYAN Index / 545
Contributors
ROBERT B. ABRAMOVITCH BENJAMIN M. DALE
Microbiology and Immunology, College of Veterinary Division of Infectious Diseases, Department of Medicine,
Medicine, Cornell University, Ithaca, NY 14853 Immunology Institute, Mount Sinai School of Medicine,
New York, NY 10029
JULIO ALIBERTI
Divisions of Molecular Immunology and Pulmonary J. MUSE DAVIS
Medicine, Cincinnati Children’s Hospital Medical Center, Immunology and Molecular Pathogenesis Program, Emory
Cincinnati, OH 45229 University, 954 Gatewood Drive, Atlanta, GA 30322
JUDITH E. ALLEN ERIC Y. DENKERS
Institutes of Evolution, Immunology and Infection Research, Department of Microbiology and Immunology, College
University of Edinburgh, Edinburgh EH9 3JT, United of Veterinary Medicine, Cornell University, Ithaca,
Kingdom NY 14853-6401
CHRISTIAN BOGDAN VOJO DERETIC
Institute of Clinical Microbiology, Immunology and Hygiene, Department of Molecular Genetics and Microbiology,
University of New Mexico School of Medicine,
University Clinic of Erlangen, Erlangen, Germany
Albuquerque, NM 87131
BARBARA BOTTAZZI
ANDREA DONI
Istituto Clinico Humanitas, IRCCS, via Manzoni 56, 20089,
Istituto Clinico Humanitas, IRCCS, via Manzoni 56, 20089,
Rozzano, Milan, Italy
Rozzano, Milan, Italy
DONNA L. BRATTON
GREGORY D. FAIRN
Cell Biology and Allergy Divisions, Department of
Programme in Cell Biology, Hospital for Sick Children,
Pediatrics, National Jewish Health, 1400 Jackson Street,
University of Toronto, Toronto, Ontario, Canada
Denver, CO 80206
ˆ
INES FARO-TRINDADE
ERIC J. BROWN
Institute of Infectious Disease and Molecular Medicine,
Department of Microbial Pathogenesis, Genentech, Inc., 1
Division of Immunology, University of Cape Town,
DNA Way, M.S. 33, South San Francisco, CA 94080
Observatory, 7925, Cape Town, South Africa
GORDON D. BROWN
CARL G. FIGDOR
Institute of Infectious Disease and Molecular Medicine,
Department of Tumor Immunology, Nijmegen Centre for
Division of Immunology, University of Cape Town,
Molecular Life Sciences, Radboud University Nijmegen
Observatory, 7925, Cape Town, South Africa
Medical Centre, Nijmegen, The Netherlands
ANDREW BRYAN KATE FITZGERALD
Department of Microbiology and Immunology, University of Division of Infectious Diseases and Immunology, Dept. of
Michigan Medical School, Ann Arbor, MI 48109-5620 Medicine, University of Massachusetts Medical School,
Worcester, MA 01605
ISABELLE CALDELARI
UPR 9022 Institut de Biologie Mole´culaireet Cellulaire, MARIA FOTI
67084 Strasbourg, France Department of Biotechnology and Bioscience, University of
Milano-Bicocca, Milano, Italy
ALESSANDRA CAMBI
Department of Tumor Immunology, Nijmegen Centre for CECILIA GARLANDA
Molecular Life Sciences, Radboud University Nijmegen Istituto Clinico Humanitas, IRCCS, via Manzoni 56, 20089,
Medical Centre, Nijmegen, The Netherlands Rozzano, Milan, Italy
vii
viii ■ CONTRIBUTORS
RICARDO T. GAZZINELLI RALPH R. ISBERG
Div. of Infectious Diseases and Immunology, Dept. of Howard Hughes Medical Institute and Department of
Medicine, University of Massachusetts Medical School, Molecular Biology and Microbiology, Tufts University
Worcester, MA 01605; Rene Rachou Institute, Oswaldo School of Medicine, 150 Harrison Avenue, Boston,
Cruz Foundation, Institute of Biological Sciences, and MA 02111
Federal University of Minas Gerais, Belo Horizonte, MG,
BABAK JAVID
Brazil
Harvard School of Public Health, 200 Longwood Avenue,
ELENA GERSHENZON Boston, MA 02115
Programme in Cell Biology, Hospital for Sick Children and
Department of Biochemistry, University of Toronto, Toronto, PASCALE JEANNIN
Ontario, Canada INSERM, U564, Equipe Avenir, 4 rue Larrey, and
University Hospital of Angers, Service d’Immunologie,
DOUGLAS T. GOLENBOCK
Angers, F-49933 France
Div. of Infectious Diseases and Immunology, Dept. of
Medicine, University of Massachusetts Medical School, FRANK KAISER
Worcester, MA 01605; Rene Rachou Institute, Oswaldo National Institute for Medical Research, Division of
Cruz Foundation, and Institute of Biological Sciences, Belo Immunoregulation, The Ridgeway, Mill Hill, London NW7
Horizonte, MG, Brazil 1AA, United Kingdom
SIAMON GORDON TACO W. KUIJPERS
Sir William Dunn School of Pathology, University of Emma Children’s Hospital, Academic Medical Centre,
Oxford, South Parks Road, Oxford OX1 3RE, United University of Amsterdam, Amsterdam, The Netherlands
Kingdom, and National Cancer Institute, National Institutes
of Health, Frederick, MD 21702-1201 VINCENT LECLERC
UPR 9022, CNRS, Institut de Biologie Mole´culaire et
JEAN-PIERRE GORVEL
Cellulaire, 67084 Strasbourg, France
Centre d’Immunologie de Marseille-Luminy, Aix Marseille
Universite´, Faculte´ de Sciences de Luminy, Case 906, ZHIRU LI
Marseille, 13288 Cedex 9, France; INSERM, U631, Department of Molecular Biology and Microbiology, Tufts
Marseille, 13288, France; and CNRS, UMR6102, Marseille, University School of Medicine, 150 Harrison Avenue,
13288, France Boston, MA 02111
FRANCESCA GRANUCCI ALBERTO MANTOVANI
Department of Biotechnology and Bioscience, University of Istituto Clinico Humanitas, IRCCS, via Manzoni 56, 20089,
Milano-Bicocca, Milano, Italy Rozzano, Milan, Italy, and Department of Translational
STEVEN GREENBERG Medicine, University of Milan, Milan, 20100, Italy
Merck Research Labs, 126 East Lincoln Ave., RY34B-348, FREDERICK R. MAXFIELD
Rahway, NJ 07065-0900
Department of Biochemistry, Weill Medical College of
SERGIO GRINSTEIN Cornell University, New York, NY 10065
Programme in Cell Biology, Hospital for Sick Children and
DENISE M. MONACK
Department of Biochemistry, University of Toronto, Toronto,
Stanford University, School of Medicine, Department of
Ontario, Canada
Microbiology and Immunology, Fairchild Building, 299
KEITH GULL Campus Drive, Stanford, CA 94305-5124
Sir William Dunn School of Pathology, University of
ALESSANDRA MORTELLARO
Oxford, South Parks Road, Oxford OX1 3RE, United
Kingdom Singapore Immunology Network (SIgN), Agency for
Science, Technology and Research (A*STAR), Singapore,
WOUTER L. W. HAZENBOS and Department of Biotechnology and Bioscience,
Department of Microbial Pathogenesis, Genentech, Inc., 1 University of Milano-Bicocca, Milano, Italy
DNA Way, M.S. 33, South San Francisco, CA 94080
DAVID M. MOSSER
THOMAS HENRY
Department of Cell Biology and Molecular Genetics and the
Stanford University, School of Medicine, Department of
Maryland Pathogen Research Institute, University of
Microbiology and Immunology, Fairchild Building, 299
Maryland, College Park, MD 20742
Campus Drive, Stanford, CA 94305-5124
SUSHMITA MUKHERJEE
PETER M. HENSON
Department of Biochemistry, Weill Medical College of
Cell Biology Division, Department of Pediatrics, National
Cornell University, New York, NY 10065
Jewish Health, 1400 Jackson Street, Denver, CO 80206
ANNE O’GARRA
DAVID W. HOLDEN
Department of Microbiology, Imperial College London, National Institute for Medical Research, Division of
London, United Kingdom Immunoregulation, The Ridgeway, Mill Hill, London NW7
1AA, United Kingdom
STEVEN M. HOLLAND
Immunopathogenesis Section, Laboratory of Clinical ANNETTE PLU¨DDEMANN
Infectious Diseases, National Institute of Allergy and Sir William Dunn School of Pathology, University of
Infectious Diseases, National Institutes of Health, Bethesda, Oxford, South Parks Road, Oxford OX1 3RE, United
MD 20892-1684 Kingdom
CONTRIBUTORS ■ ix
LALITA RAMAKRISHNAN FREDERICK S. SOUTHWICK
Department of Microbiology, University of Washington, Gainesville, FL 32610-0275
1959 NE Pacific Street, Seattle, WA 98195
JOEL A. SWANSON
SARA M. RANKIN Department of Microbiology and Immunology, University of
Leukocyte Biology Section, NHLI Division, Faculty of Michigan Medical School, Ann Arbor, MI 48109-0620
Medicine, Imperial College London, South Kensington
Campus, Exhibition Road, London SW7 2AZ, United MICHELE S. SWANSON
Kingdom Department of Microbiology and Immunology, University of
Michigan Medical School, Ann Arbor, MI 48109-5620
JEAN-MARC REICHHART
UPR 9022 Institut de Biologie Mole´culaireet Cellulaire, JESSICA A. THOMPSON
67084 Strasbourg, France Department of Microbiology, Imperial College London,
PAOLA RICCIARDI-CASTAGNOLI London, United Kingdom
Singapore Immunology Network (SIgN), Agency for GUY TRAN VAN NHIEU
Science, Technology and Research (A*STAR), Singapore,
Unite´ de Communication Intercellulaire et Infections
and Department of Biotechnology and Bioscience,
Microbiennes, Inserm U971, Colle`gede France, 11, Place
University of Milano-Bicocca, Milano, Italy
Marcelin Berthelot, 75005 Paris, France
ANNE J. RIDLEY
TIMO K. VAN DEN BERG
King’s College London, Randall Division of Cell and
Molecular Biophysics, New Hunt’s House, Guy’s Campus, Sanquin Research at CLB, and Landsteiner Laboratory,
London SE1 1UL, United Kingdom Academic Medical Center, University of Amsterdam,
Amsterdam, The Netherlands
KYLE H. ROHDE
Microbiology and Immunology, College of Veterinary NATALIA VERESHCHAGHINA
Medicine, Cornell University, Ithaca, NY 14853 Neuroscience and Behavioral Disorders, Laboratory of Neural
Stem Cell, Duke-NUS (National University of Singapore)
DIRK ROOS
Graduate Medical School, 2 Julan Bukit Merah,
Sanquin Research at CLB, and Landsteiner Laboratory,
Singapore 169547
Academic Medical Center, University of Amsterdam,
Amsterdam, The Netherlands DONALD C. VINH
ERIC J. RUBIN Immunopathogenesis Section, Laboratory of Clinical
Harvard School of Public Health, 200 Longwood Avenue, Infectious Diseases, National Institute of Allergy and
Boston, MA 02115 Infectious Diseases, National Institutes of Health, Bethesda,
MD 20892-1684
DAVID G. RUSSELL
Microbiology and Immunology, College of Veterinary ANN P. WHEELER
Medicine, Cornell University, Ithaca, NY 14853 Queen Mary University of London, Institute of Cell and
Molecular Science, Barts, and The London School of
SUZANA P. SALCEDO
Medicine and Dentistry, Blizard Building, 4 Newark St.,
Centre d’Immunologie de Marseille-Luminy, Aix Marseille
Universite´, Faculte´ de Sciences de Luminy, Case 906, London E1 2AT, United Kingdom
Marseille, 13288 Cedex 9, France; INSERM, U631, TIMOTHY J. WILLIAMS
Marseille, 13288, France; and CNRS, UMR6102, Marseille,
Leukocyte Biology Section, NHLI Division, Faculty of
13288, France
Medicine, Imperial College London, South Kensington
GIOVANNI SALVATORI Campus, Exhibition Road, London SW7 2AZ, United
Sigma-Tau R&D, via Pontina Km 30.400, 00040, Pomezia, Kingdom
Rome, Italy
THOMAS A. WYNN
PHILIPPE SANSONETTI
Immunopathogenesis Section, National Institute of Allergy
Unite´ de Pathoge´nieMicrobienne Mole´culaire, Institut
and Infectious Diseases, National Institutes of Health,
Pasteur, 28, rue du Dr. Roux, 75724 Paris Cedex 15, France
Bethesda, MD 20892-8003
CHARLES N. SERHAN
ROBIN M. YATES
Center for Experimental Therapeutics and Reperfusion
Microbiology and Immunology, College of Veterinary
Injury, Department of Anesthesiology, Perioperative and
Medicine, Cornell University, Ithaca, NY 14853
Pain Medicine, Brigham and Women’s Hospital and Harvard
Medical School, Boston, MA 02115 XIA ZHANG
SAMUEL C. SILVERSTEIN Department of Cell Biology and Molecular Genetics and the
Department of Physiology and Cellular Biophysics, Columbia Maryland Pathogen Research Institute, University of
University, New York, NY 10032 Maryland, College Park, MD 20742