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About Paper 1333
Assessment the biochemical and genetic changes of congenital and cataractous lenses of patients. In this study, 15 congenital and 56 senile cataractous lenses obtained from patients admitted to Ophthalmic Center, Mansoura University Hospital, Mansoura, Egypt were investigated. Non-opaque lenses were extracted from infants (n=5) and adult 20-30 years (n=6) after death of 1-4 hours. The study was approved by the Department of Evaluation and Quality Assurance of the Mansoura University of Human Research Ethics committee, Egypt. A written informed consent had been taken beforehand from all patients to use their extracted lens experimentally after operation. Isoenzyme electrophoresis was carried out for both control and experimental groups. isoenzyme electrophoresis of carbonic anhydrase, lactic dehydrogenase, esterase and superoxide dismutase was carried out for both control and experimental groups. The present findings revealed marked alterations of the assayed isoenzymes expression. Different factors are involved in cataractous formation and all contributed to the oxidative stress which altered the isoenzyme fractions contributed to the metabolism lens components. Keywords: Congenital & senile cataractous lenses, isoenzyme electrophoresis.
Detailed Information
| Author: | ['IJARBS JOURNAL'] |
|---|---|
| Publication Year: | 2015 |
| Pages: | 6 |
| Language: | English |
| Format: | |
| Price: | FREE |
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