Table Of ContentOxford Case Histories in 
Respiratory Medicine
OXFORD CASE HISTORIES 
Series Editors
Peter Rothwell and Sarah Pendlebury 
 Published: 
 Neurological Case Histories  (Sarah Pendlebury and Peter Rothwell)
 Oxford Case Histories in Gastroenterology and Hepatology  (Alissa 
Walsh, Otto Buchel, Jane Collier, and Simon Travis)
O  xford Case Histories in Respiratory Medicine  (John Stradling, Andrew 
Stanton, Najib Rahman, Annabel Nickol, and Helen Davies)
 Forthcoming: 
 Oxford Case Histories in Cardiology  (Colin Forfar, Javed Ehtisham and 
Rajkumar Rajendram)
O  xford Case Histories in Nephrology  (Chris Pugh, Chris O’Callaghan, 
Aron Chakera, Richard Cornall and David Mole)
O  xford Case Histories in Rheumatology  (Joel David, Anne Miller, 
Anushka Soni and Lyn Williamson)
 Oxford Case Histories in Stroke and TIA  (Sarah Pendlebury and Peter 
Rothwell)
Oxford Case 
Histories in 
Respiratory
Medicine
John Stradling 
Professor of Respiratory Medicine, Oxford University, 
Consultant Physician, Oxford Centre for Respiratory 
Medicine, Churchill Hospital, Oxford 
Andrew Stanton 
Specialist Registrar in Respiratory Medicine 
Oxford Centre for Respiratory Medicine 
Churchill Hospital, Oxford 
Najib Rahman 
Specialist Registrar and MRC Training Fellow 
Oxford Centre for Respiratory Medicine 
Churchill Hospital, Oxford 
Annabel Nickol 
Clinical Lecturer in Respiratory Medicine 
Oxford Centre for Respiratory Medicine 
Churchill Hospital, Oxford 
Helen Davies 
Specialist Registrar in Respiratory Medicine 
Oxford Centre for Respiratory Medicine 
Churchill Hospital, Oxford 
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A note from the series editors 
Case histories have always had an important role in medical education, but 
most published material has been directed at undergraduates or residents. The 
Oxford Case Histories series aims to provide more complex case-based learn-
ing for clinicians in specialist training and consultants, with a view to aiding 
preparation for entry and exit-level specialty examinations or revalidation. 
Each case book follows the same format with approximately 50 cases, each 
comprising a brief clinical history and investigations, followed by questions on 
differential diagnosis and management, and detailed answers with discussion. 
All cases are peer-reviewed by Oxford consultants in the relevant specialty. At 
the end of each book, cases are listed by mode of presentation, aetiology and 
diagnosis.
We are grateful to our colleagues in the various medical specialties for their 
enthusiasm and hard work in making the series possible.
Sarah Pendlebury and Peter Rothwell
 Quotes on the first book in the series – “Neurological Case Histories” 
“I recommend this excellent volume highly ....... this book will enlighten and 
entertain consultants, and all readers will learn something.”
Lancet Neurology 2007; 6: 951
“This short and well-written text is …. designed to enhance the reader’s diag-
nostic ability and clinical understanding …. A well documented and practical 
book”
European Journal of Neurology 2007; 14: e19
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Introduction
 Postgraduate medical education has changed considerably over the last 
30 years. There is greater emphasis on structured learning, but apprenticeship 
time has decreased. Thus specialist registrars may reach the end of their t raining 
without having seen cases of either rare diseases, rare presentations of c ommon 
diseases or unusual problems in association with common diseases. Most phy-
sicians learn from cases they have seen. This collection of cases is a second-best 
alternative, providing vignettes that hopefully will come to mind when a 
 similar case is encountered in the future. 
 The cases are not meant to comprehensively cover the ‘syllabus’ of a specialist 
registrar in respiratory medicine, but are selected for their interest, or to eluci-
date points that the authors feel are important but may be under-appreciated. 
The style of presentation thus inevitably varies depending on the type of message 
and some of the problems discussed have no right answer, ours may well be 
disputed!
W  e hope the question-and-answer format will keep the reader on their toes 
and make reading through the cases more fun.
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Acknowledgements
M  any people have given their time to read through these cases and correct 
errors or improve clarity. We are very grateful for their input; in particular 
Rachel Benamore has provided considerable help with the radiology, and Rolf 
Smith read through all the cases to provide us with invaluable help. These are 
the individuals who reviewed one or more cases for us: Lesley Bennett, 
Malcolm Benson, Di Bilton, Steve Chapman, Sonya Craig, Ling-Pei Ho, Rob 
Davies, Colin Forfar, Maxine Hardinge, Robin Howard, Gary Lee, Raashid 
Luqmani, Lorna McWilliam, Grace Robinson, Rana Sayeed, Claire Shovlin, 
Catherine Swales, Catherine Thomas, Chris Winearls, and John Wrightson. 
Needless to say any errors remain our responsibility.