Table Of ContentOveractive Bladder
Practical Management
Overactive Bladder
Practical Management
EditEd by
Jacques Corcos MD, FRCS(S)
Professor of Urology
department of Urology
McGill University
Montreal, QC, Canada
Scott MacDiarmid MD, FRCPSC
director
bladder Control and Pelvic Pain Center
Alliance Urology Specialists
Greensboro, NC, USA
John Heesakkers MD, PhD
Urologist
department of Urology
Radboud University Medical Center
Nijmegen, the Netherlands
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Library of Congress Cataloging‐in‐Publication Data
Overactive bladder (Corcos)
Overactive bladder : practical management / edited by Jacques Corcos, Scott Macdiarmid, John Heesakkers.
p. ; cm.
includes bibliographical references and index.
iSbN 978-1-118-64061-6 (cloth)
i. Corcos, Jacques, editor. ii. Macdiarmid, Scott A., editor. iii. Heesakkers, John, editor. iV. title.
[dNLM: 1. Urinary bladder, Overactive–therapy. WJ 500]
RC919
616.6′2–dc23
2015004410
A catalogue record for this book is available from the british Library.
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Set in 9.5/13pt Meridien by SPi Publisher Services, Pondicherry, india
1 2015
Contents
Contributors, vii Section 4: Second Line
Management
Forewords, ix
Preface, xiv 9 Oral medication for
overactive bladder, 85
Roger Dmochowski and Jill Danford
Section 1: Introduction
10 Patches and gels, 91
1 Overactive bladder: terminology L.N. Plowright and G.W. Davila
and problem spectrum, 3
11 Promising experimental drugs and
John Heesakkers
drug targets, 100
2 Pathophysiology, 7 Karl‐Erik Andersson
Mathieu Boudes and Dirk De Ridder
12 The role of co‐medication in
the treatment of OAB, 118
Section 2: Evaluation Nadir I. Osman and Christopher R.
Chapple
3 Timing for evaluation, 25
Jack C. Hou and Philippe E. Zimmern 13 Other non‐surgical approaches for the
treatment of overactive bladder, 129
4 Clinical evaluation, 29
Geneviève Nadeau and Sender Herschorn
Anand Singh and Vik Khullar
5 Urodynamic evaluation of
the overactive bladder, 43 Section 5: Third Line
Barry G. Hallner, Ryan M. Krlin Management
and J. Christian Winters 14 Maximizing the treatment of
6 Other testing, 53 overactive bladder with sacral
Hessel Wijkstra and Lara C. nerve stimulation, 141
Gerbrandy‐Schreuders Scott MacDiarmid
15 Posterior tibial nerve stimulation, 154
John Heesakkers
Section 3: First Line Management
16 Botulinum toxin for the overactive
7 Changes in lifestyle, 65
bladder, 164
Diane K. Newman
Apostolos Apostolidis
8 Physical therapy, 76
Kari Bø
v
vi Contents
Section 6: Surgery 19 Bladder outlet obstruction
and the overactive bladder, 222
17 Surgical treatment for overactive
Nadir I. Osman and Christopher
bladder, 191
R. Chapple
Jerzy B. Gajewski and Fadi Sawaqed
20 Synthesis of practical approaches to
overactive bladder, 233
Section 7: Special Populations and
Jacques Corcos
Synthesis
18 Overactive bladder in older people, 205
Index, 238
Adrian Wagg
Contributors
Karl‐Erik Andersson, MD, PhD Jill Danford, MD
Faculty of Health, Institute for Clinical Medicine Vanderbilt University
University of Arhus Medical Center, Nashville, USA
Arhus, Denmark
G.W. Davila, MD
Apostolos Apostolidis, MD, PhD, FEBU Cleveland Clinic Florida
Assistant Professor of Urology‐Neurourology Weston/Fort Lauderdale, FL, USA
Second Department of Urology,
Papageorgiou General Hospital, Aristotle
Dirk De Ridder, MD, PhD, FEBU
University of Thessaloniki
Laboratory of Experimental Urology
Thessaloniki, Greece
Department of Development
and Regeneration
Kari Bø, PhD KU Leuven
Professor of Exercise Science
Leuven, Belgium
Norwegian School of Sport Sciences,
Department of Sports Medicine
Roger Dmochowski, MD, FACS
Oslo, Norway
Professor of Urology / Gynecology
Vanderbilt University Medical Center
Mathieu Boudes, PhD
Nashville, TN, USA
Laboratory of Experimental Urology
Department of Development and Regeneration
KU Leuven, Leuven, Belgium Jerzy B. Gajewski, MD, FRCSC
Professor of Urology & Pharmacology
Dalhousie University
Christopher R. Chapple, BSc, MD,
Halifax, NS, Canada
FRCS (Urol), FEBU
Consultant Urological Surgeon, Department
of Urology, Royal Hallamshire Hospital Lara C. Gerbrandy‐Schreuders, MD
Honorary Senior Lecturer of Urology, Department of Urology
University of Sheffield AMC University Hospital
Visiting Professor of Urology Amsterdam, The Netherlands
Sheffield Hallam University
Sheffield, UK Barry G. Hallner Jr, MD
Female Pelvic Medicine and
Jacques Corcos, MD, FRCS(S) Reconstructive Surgery
Professor of Urology Department of Obstetrics & Gynecology
Department of Urology Louisiana State University Health
McGill University Sciences Center
Montreal, QC, Canada New Orleans, LA, USA
vii
viii Contributors
John Heesakkers, MD, PhD Nadir I. Osman, MBChB (hons), MRCS
Department of Urology Department of Urology
Radboud University Medical Center Royal Hallamshire Hospital
Nijmegen, The Netherlands Sheffield, UK
Sender Herschorn, BSc, MD, FRCSC L.N. Plowright, MD
Sunnybrook Health Sciences Centre Cleveland Clinic Florida
University of Toronto Weston/Fort Lauderdale, FL, USA
Toronto, ON, Canada.
Fadi Sawaqed, MD
Jack C. Hou, MD Dalhousie University
UT Southwestern Medical Center Halifax, Canada
Dallas, TX, USA
Anand Singh, MBBS, BSc
Vik Khullar, BSc, FRCOG, MD, AKC Specialist Trainee in Obstetrics and
Consultant Urogynaecologist Gynaecology
St. Mary’s Hospital, NHS Trust Clinical Research Fellow in Urogynaecology
Imperial College London St. Mary’s Hospital, NHS Trust
London, UK Imperial College London
London, UK
Ryan M. Krlin, MD
Assistant Professor of Urology Adrian Wagg, MBBS, FRCP, FRCP (E), FHEA
Department of Urology Research Chair in Healthy Ageing
Louisiana State University School of Medicine Department of Medicine,
New Orleans, LA, USA University of Alberta
Edmonton, AB, Canada
Scott MacDiarmid, MD, FRCPSC
Director Hessel Wijkstra, MSc, PhD
Bladder Control and Pelvic Pain Center Department of Urology
Alliance Urology Specialists AMC University Hospital
Greensboro, NC, USA Amsterdam, The Netherlands
Geneviève Nadeau, MD, M.Sc, FRCSC J. Christian Winters, MD, FACS
Division of Urology Professor and Chairman, Department
Centre Hospitalier de l’Université de Québec of Urology
Québec, QC, Canada. Louisiana State University Health Sciences
Center
Diane K. Newman, DNP, ANP‐BC, FAAN New Orleans, LA, USA
Research Investigator Senior and Adjunct
Associate Professor of Urology in Surgery Philippe E. Zimmern, MD
Perelman School of Medicine, University UT Southwestern Medical Center
of Pennsylvania Dallas, TX, USA
Co-Director of the Penn Center for Continence
and Pelvic Health
Division of Urology, University of Pennsylvania
Medical Center, Philadelphia, PA, USA