Optimizing living donor nephrectomy

172 Pages·2013·2.08 MB·English

by  Nienke Dols

Optimizing living donor nephrectomy
Eligibility and surgical techniques
Nienke Dols
The studies described in this thesis were performed at the Department of Surgery,
Erasmus MC, Rotterdam, the Netherlands.
This research was fnancially supported by Nuts-Ohra and Erasmus MC Cost-Efectiveness
Research (Doelmatigheidsonderzoek).
Financial support for the printing of this thesis was obtained from:
Applied Medical
Astellas Pharma
Chipsoft
Erasmus MC – afdeling Heelkunde
Johnson & Johnson Medical
Nederlandse Transplantatie Vereniging
Roche Nederland
Sint Franciscus Gasthuis
Takeda Nederland
Vrest Medical
ISBN: 978-94-6169-428-7
Layout and printing: Optima Grafsche Communicatie, Rotterdam, The Netherlands
Optimizing living donor nephrectomy:
Eligibility and surgical techniques
Nierdonatie bij leven:
optimaliseren van donor selectie en chirurgische technieken
Proefschrift
ter verkrijging van de graad van doctor aan de
Erasmus Universiteit Rotterdam
op gezag van de rector magnifcus
Prof.dr. H.G. Schmidt
en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
vrijdag 1 november 2013 om 11:30
door
Leonienke Francisca Cornelia Dols
geboren te Rotterdam
PrOmOtiECOmmissiE
Promotor: Prof.dr. J.N.M. IJzermans
Overige leden: Prof.dr. W. Weimar
Prof.dr. H.W. Tilanus
Prof.dr. D.A. Legemate
Copromotor: Dr. N.F.M. Kok
COntEnts
Chapter 1 introduction 9
Adapted from ‘Live donor nephrectomy: a review of evidence for
surgical techniques’, Transplant International 2009, ‘Laparoscopic
living kidney donation’, book chapter in ‘Laparoscopy, an
interdisciplinary approach’ and ‘Surgical aspects of live kidney
donation’, Frontiers in bioscience 2009
Chapter 2 Living kidney donors: impact of age on long-term safety. 21
American Journal of Transplantation 2011
Chapter 3 Complex vascular anatomy in live kidney donation: imaging 35
and consequences for clinical outcome.
Transplantation 2008
Chapter 4 Laparoscopic donor nephrectomy: a plea for the right-sided 49
approach.
Transplantation 2009
Chapter 5 Attitudes among surgeons towards live-donor nephrectomy: 63
a European update.
Transplantation 2012
Chapter 6 Long-term follow-up of a randomized trial comparing 79
laparoscopic and mini-incision open live donor nephrectomy.
American Journal of Transplantation 2010
Chapter 7 Optimizing live kidney donation: Hand-assisted 93
retroperitoneoscopic as alternative to standard laparoscopic
donor nephrectomy.
Transplant International 2010
Chapter 8 Hand-assisted retroperitoneoscopic versus standard 105
laparoscopic donor nephrectomy: HArP-trial.
BMC Surgery 2010
Chapter 9 randomised controlled trial on live donors’ comfort and 117
safety during and after hand-assisted retroperitoneoscopic
versus standard laparoscopic donor nephrectomy.
Transplantation, In press
Chapter 10 Ergonomics during live kidney donation: comparing the 135
hand-assisted retroperitoneal and laparoscopic approach.
Submitted
Chapter 11 summary in English and Dutch 149
Chapter 12 General discussion, recommendations and future 165
perspectives
Appendices Contributing authors 175
Dankwoord 177
List of publications 181
PhD portfolio 185
Curriculum Vitae 187
Chapter 1
Introduction
L.F.C. Dols1, N.F.M. Kok1 and J.N.M. IJzermans1
1Department of Surgery, Erasmus MC, Rotterdam, The Netherlands
Adapted from:
‘Live donor nephrectomy: a review of evidence for surgical techniques’,
Transplant International 2009, ‘Laparoscopic living kidney donation’,
book chapter in ‘Laparoscopy, an interdisciplinary approach’ and ‘Surgical
aspects of live kidney donation’, Frontiers in bioscience 2009