Operating Rooms

84 Pages·2016·4.8 MB·English

INDEX
PRESENTATION 4
INTRODUCTION 5
HEAlTHCARE ACTIvITIES 7
Quality at OPBG: experiences with Joint Commission International Accreditation 8
Description of Healthcare Activities 9
Safety 13
Activities of Healthcare Professions 14
Family-Centred Care: the “Therapy of Care” 15

ACTIvITIES Of THE DEPARTmENTS 19
Surgical Department 20
Department of Emergency Admissions and Anaesthesiology/Resuscitation/Operating Rooms 24
Imaging Department 25
Laboratories Department 26
Medical-Surgical Department of Paediatric Cardiology 27
Department of Paediatric Medicine 28
Department of Medical and Surgical Neonatology 30
Department of Neurosciences and Neurorehabilitation 31
Department of Nephrology and Urology 33
Department of Oncohaematology and Transfusion Medicine 34
University-Hospital Paediatric Department 35

SCIENTIfIC ACTIvITIES 37
Research activity 38
Scientific output 40
Research funding 41

RESEARCH AREAS 43
Genetic Diseases and Rare Diseases Research Area 44
Multifactorial Diseases and Complex Phenotypes Research Area 46
Immunology and Drug Therapy Research Area 47
Oncohaematology Research Area 48
Clinical-Technological Innovation Research Area 50
Clinical Care and Management Innovations Research Area 51

PUBlICATIONS 2015 55
AUTHOR INDEX 73
PRESENTATION
This is the second time I have the honour of presenting the annual report of the Ospedale Pediatrico
Bambino Gesù’s activities. The numbers are encouraging, and this is why I wish to thank the entire
hospital community which makes sure we achieve our real mission: to continue providing the best
and most diligent care to the children of Rome, of our Lazio Region and even of other Regions
and countries.
Our hospital is opening even more its doors to the world, not only in its willingness to provide care
for children from all continents, but also to give our doctors and researchers the best opportunities
for training and for clinical and scientific collaboration with colleagues and with the most prestigious
international institutions. Our hospital, for its highest standards in scientific research as well as for
the amount, the complexity and the quality of clinical care it provides, is one of the most important
paediatric hospitals in Europe and in the world.
Therefore, thanks to these results, we have decided this year to present this Report on the Hospital’s
Health care and scientific activities in an appropriate and prestigious venue, The Pontifical Academy
of Sciences, in the Casina Pio IV, inside Vatican City. It is a way for us to return the fruits of our work
to the Holy See and to share the challenges and the difficulties we have faced, but also our great
enthusiasm, our pride in the results we’ve achieved, our joy and the inestimable satisfaction of caring
for so many lives.
In these pages the Hospital’s community tells its story with the rigor and transparency that have always
characterized clinical and scientific reports, which are necessarily based on numbers, evidences and
publications. Behind each single result though there is the heart-felt work of many people constantly
striving for excellence and innovation, there are the many patients who have been cared for and families
that have been welcomed, heard and supported in their difficult and painful journeys. An extraordinary
work of intelligence and charity that deserves to be shared and told.
Mariella Enoc
President of Ospedale Pediatrico Bambino Gesù
INTRODUCTION
The 2015 yearbook for the Bambino Gesù Paediatric Hospital (Ospedale Pediatrico Bambino Gesù),
produced jointly by the Healthcare Department and the Scientific Department, provides details of the
most significant clinical, healthcare and research activities undertaken in the course of a year that has been
particularly important, not only in terms of the results achieved but also because of the new developments
taking place, and primarily the appointment of Dr Mariella Enoc as Chair of the Hospital Board. Dr Enoc
has made a huge contribution to optimising and promoting the Hospital’s mission, which is guided, in
terms of its component principles, by the universal values of Christian Charity. This mission drives and
promotes the continued progress of our Hospital, which, thanks to of the excellence of its medical services
and the significant degree of integration of those services with research activities, is intended to achieve the
most effective possible translational outcomes. This is a project that prioritises the central position of the
individual, giving full recognition and respect to the dignity of the child, the parents and the healthcare
professionals involved. The clinical activities undertaken over the year have been capped by the prestigious
recognition as an academic teaching hospital by the Joint Commission International (JCI), in cooperation
with the Chair of Paediatrics of the Università di Tor Vergata, and coincided with the confirmation, for the
fourth time, of JCI accreditation, underlining the quality of the care provided and of the organisation.
In strictly clinical terms, we should highlight the remarkable performance level achieved in terms of
diagnosis and treatment of patients suffering from rare diseases, in some cases through systematic
application of the case management method, which makes it possible for the family and the child to have
a single point of contact who is able to guide them in their relationships with the various specialists, in
managing the therapeutic pathway for the patient. Furthermore, the results for organ and tissue transplants
continue to be excellent (326, +4% compared to 2014), thus allowing the Hospital to maintain its leading
role both nationally and internationally in the complex sector of paediatric transplantology.
OPBG’s clinical activities have been given an extraordinary boost by the research programmes implemented
in the Clinical Trial Centre, a unit created to foster the development of innovative treatment models
through advanced pharmacological trials. In recent years, the Centre has contributed to promoting
the excellence of clinical trials in paediatrics and to providing professionals with the tools necessary
for performance of high-quality scientific research. Research activities have seen a consolidation and
reinforcement of the trend towards the growth of all parameters for measurement of scientific results,
including the total value of the Impact Factor (IF) indicator, which ranks OPBG as one of the leading
institutions in the network of Italian Institution for Healthcare and Research and top among facilities that
do not include a university. In particular: the absolute number of scientific publications indexed, which has
surpassed the figure of 560 publications; the IF value produced by the individual researchers; the percentage
of publications completed as part of cooperative international networks; and the resources attracted for
research. The translational nature of these activities has been manifested, among other things, by the
development of new treatment protocols, the identification of the biological basis for numerous diseases,
the development of new diagnostic tests and the isolation of disease genes. One important investment made
during the year involved the strengthening of the area of immunological research, which will take off in
2016 with the opening of new laboratories. Although the historical context has been uncertain and difficult,
the OPBG has continued to pursue its objective of continual improvement of its activities. The presence
of a single unit comprising all paediatric disciplines provides children and their family groups with highly
qualified experts who are able to design and implement the most appropriate clinical and care pathway,
using a holistic approach to the disease. In this sense, ours is a privileged Hospital because the synergy
between care and research creates added value for the benefit of our young patients.
Bruno Dallapiccola Scientific Director
Massimiliano Raponi Healthcare Director

HEAlTHCARE
ACTIvITIES
Quality at OPBG:
experiences with Joint Commission
International Accreditation
In 2015, the Ospedale Pediatrico Bambino Gesù was of the quality of care’ and the parameters to be achieved
accredited in terms of quality for the fourth time by refer to all aspects of the hospital organisation: procedures
Joint Commission International (JCI), the principal for care, education of patients and their families, safety of
international accreditation body in the medical sphere. infrastructure and treatment practices, qualification and
Following a rigorous review, the JCI inspectors certified training of personnel, control of healthcare-associated
the compliance of the OPBG according to international infections, and management of information. For hospi-
standards of excellence, confirming its commitment to
tals like the OPBG where medical training and clinical
guaranteeing that the littlest patients have access to care
research are also undertaken, there are additional require-
that is safe and effective. Cooperation with the Università
ments to be met in order to obtain recognition as an ‘Ac-
di Tor Vergata has made it possible for the Hospital to
ademic Medical Teaching Centre’.
achieve the additional objective of recognition as an aca-
demic teaching hospital in 2015.
Joint Commission International was founded in 1994
as an international branch of The Joint Commission,
The OPBG was first accredited by JCI in 2006, with this
the leading and largest body in the United States for ac-
recognition being confirmed subsequently in 2009 and
creditation and determination of medical and healthcare
2012, on a three-year basis. During the accreditation
visits, the international team evaluated the Hospital’s standards. It is a non-profit entity with a presence in more
compliance with medical standards that are developed than 90 countries working to improve patient safety and
and updated periodically through discussion with experts quality of healthcare, and it is considered the gold stand-
from around the world, the scientific literature and good ard in healthcare worldwide. In Italy, there are a total of
practices adopted internationally. The JCI method is in 24 medical organisations accredited by JCI. Of these, 14
fact based on the concept of ‘continuous improvement are accredited as hospitals and five as teaching hospitals.
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HEALTHCARE AND SCIENTIFIC ACTIVITIES - SUMMARY 2015