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Oncogene-Directed Therapies (Cancer Drug Discovery and Development) PDF

501 Pages·2002·3.425 MB·English
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by Janusz W. Rak| 2002| 501 pages| 3.425| English

About Oncogene-Directed Therapies (Cancer Drug Discovery and Development)

Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.

Detailed Information

Author:Janusz W. Rak
Publication Year:2002
ISBN:9781592593132
Pages:501
Language:English
File Size:3.425
Format:PDF
Price:FREE
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