Table Of ContentNutritional Influences
on Bone Health
10th International Symposium
Connie M. Weaver
Heike Bischoff-Ferrari
Robin M. Daly
Man-Sau Wong
Editors
123
Nutritional Influences on Bone Health
Connie M. Weaver • Heike Bischoff-Ferrari
Robin M. Daly • Man-Sau Wong
Editors
Nutritional Influences
on Bone Health
10th International Symposium
Editors
Connie M. Weaver Heike Bischoff-Ferrari
Nutrition and Science Geriatrics and Aging Research
Purdue University University of Zurich
West Lafayette, IN Zurich
USA Switzerland
Robin M. Daly Man-Sau Wong
Institute for Physical Activity and Nutrition Department of Applied Biology
Deakin University and Chemical Technology
Melbourne The Hong Kong Polytechnic University
Victoria Hung Hom
Australia Hong Kong
ISBN 978-3-319-98463-6 ISBN 978-3-319-98464-3 (eBook)
https://doi.org/10.1007/978-3-319-98464-3
Library of Congress Control Number: 2018957853
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Preface
The 10th International Symposium on Nutritional Aspects of Osteoporosis in Hong
Kong continued the valued opportunity for scientists and students interested in the
role of nutrition to optimize bone and muscle health to spend time devoted to this
topic exclusively.
Hong Kong brought more participation from the Asian region. The prevalence of
fractures in Asia illustrates the urgency of prevention. And what an exciting venue
Hong Kong was for the delegates that attended this meeting. Being in such a
dynamic city added a great deal of enjoyment to the meeting. We are grateful to
Dawn Haan at Purdue University, the staff at the Hong Kong Polytechnic University,
and the staff at the Federation of Medical Societies of Hong Kong for their admin-
istrative support of this international meeting.
The Proceedings reflect a mixture of reviews, study designs of ongoing major
trials, and research presentations that characterized the meeting. The editors hope
that the Proceedings make a contribution to the field.
West Lafayette, IN, USA Connie M. Weaver
Melbourne, VIC, Australia Robin M. Daly
Hung Hom, Hong Kong Man-sau Wong
Zurich, Switzerland Heike Bischoff-Ferrari
v
Contents
Part I V itamin D
1 DO-HEALTH: Vitamin D3-Omega-3-Home Exercise-Healthy
Aging and Longevity Trial—Dietary Patterns in Five European
Countries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Patricia O. Chocano-Bedoya and Heike A. Bischoff-Ferrari
2 Vitamin D and Omega-3 Fatty Acid Trial 2017: Addressing
Effects on Muscle and Bone . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Meryl S. LeBoff, Catherine M. Donlon, Sharon H. Chou,
Nancy Cook, Julie Buring, and JoAnn E. Manson
3 Vitamin D Among Children in Asia . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Tsz Ping Lam, Benjamin Hon Kei Yip, Wayne Y. W. Lee,
Nelson Leung Sang Tang, Kwong Man Lee, Alec Lik Hang Hung,
Bobby Kin Wah Ng, and Jack Chun Yiu Cheng
Part II M icronutrients: Calcium, Sodium, and Potassium
4 Peak BMC Growth and Calcium Requirements for Children . . . . . . 37
Michael R. Lawlor, Connie M. Weaver, Bruce A. Craig,
Susan J. Whiting, Adam D. G. Baxter-Jones, Hassanali Vatanparast,
and George P. McCabe
5 Integrative Omic Study to Identify Potential Dietary
Supplement for Osteoporosis Treatment . . . . . . . . . . . . . . . . . . . . . . . 45
Ching-Lung Cheung
6 Dietary Mineral Intake Ratios and Bone Health in Adults . . . . . . . . . 53
Andrea J. Lobene, Linda D. McCabe, Michael S. Stone,
Joseph M. Kindler, Regan L. Bailey, Alanna J. Moshfegh,
Donna G. Rhodes, Joseph D. Goldman, George P. McCabe,
and Connie M. Weaver
vii
viii Contents
7 Dietary Calcium, Lifestyle Factors, and Bone Health
in Premenarche Chinese Girls . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69
Gordon C. L. Cheung and Yi-Xiang Su
Part III Exercise/Sedentary Behavior
8 Nutrition and Exercise Approaches to Enhance Muscle,
Mobility, and Cognition During Aging . . . . . . . . . . . . . . . . . . . . . . . . . 77
Robin M. Daly, Melissa B. Formica, Jamie L. Tait,
and Helen Macpherson
9 Sedentary Behaviors in Children and Adolescents:
What Is the Influence on Bone Strength? . . . . . . . . . . . . . . . . . . . . . . . 95
Simon Higgins, Staci L. Belcher, and Richard D. Lewis
10 Effects of Low Energy Availability on Bone Health
in Exercising Premenopausal Women . . . . . . . . . . . . . . . . . . . . . . . . . . 109
Nancy I. Williams and Mary Jane De Souza
11 Lifestyle Intervention to Improve Mobility in Apparently
Healthy Chinese Elders: A Hypothesis Generating Study . . . . . . . . . 127
Marie-Noelle Horcajada and Elizabeth A. Offord
Part IV Prebiotics
12 Diet, Microbiota, and Bone Health . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143
René Rizzoli
13 Therapeutic Targeting of Gut-Bone Signaling
to Treat Osteoporosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169
Laura R. McCabe and Narayanan Parameswaran
14 Meeting Calcium Needs in Asia and Prebiotic Study Protocol . . . . . . 183
Winnie Chee, Kanimolli Arasu, Chang Chung Yuan,
Soon Yee Wong, Ong Shu Hwa, Wai Yew Yang, Megan Chong,
Meenal Mavinkurve, and Jia Yuan Khoo
Part V B ioactives/Functional Foods
15 Effect of Dried Plum on Bone Biomarkers in Men . . . . . . . . . . . . . . . 193
Shirin Hooshmand
16 Bone-Protective Chinese Herbs: The Story
of Fructus Ligustri Lucidi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199
Sisi Cao, Xiao-Li Dong, Yan Zhang, and Man-Sau Wong
Contents ix
Part VI Diet Patterns/Micronutrients
17 The Relationship Between Dietary Fat and Sarcopenia,
Skeletal Muscle Loss, Osteoporosis and Risk
of Fractures in Aging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211
Ailsa A. Welch and Richard P. G. Hayhoe
18 Dairy Products, Vitamin D, and Bone Health . . . . . . . . . . . . . . . . . . . 227
Laura H. van Dongen and S. Sahni
19 Dietary Intake in Chinese Community- Dwelling Older
Adults with Sarcopenia: A Focus on Protein . . . . . . . . . . . . . . . . . . . . 237
Ruth Chan and Liu-Ying Zhu
Part VII Policy and Translation
20 No Relationship Between Serum 25(OH) Vitamin D
Concentrations and Perceptions of Vitamin D Dietary
Intake Adequacy in US and German Adults Not Using
Dietary Supplements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 247
Regan L. Bailey, Sowmyanarayanan V. Thuppal,
Katherine D. Sherif, Nigel Denby, Suzanne R. Steinbaum,
Bryan Haycock, Alexandra E. Cowan, Jared R. Nieters,
and Clemens von Schacky
21 Building and Translating Evidence- Based Nutrition
and Bone Research Into Policy and Public Health Messaging . . . . . . 257
Taylor C. Wallace
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269
Part I
Vitamin D
DO-HEALTH: Vitamin D3-Omega-3-Home 1
Exercise-Healthy Aging and Longevity
Trial—Dietary Patterns in Five European
Countries
Patricia O. Chocano-Bedoya and Heike A. Bischoff-Ferrari
Introduction
The increasing number of older adults worldwide poses an important public health
challenge [1]. For instance, in the USA, seniors 65 and over grew from 35.0 million
in 2000 to 49.2 million in 2016, accounting for 12.4% and 15.2% of the total popu-
lation, respectively, and they are estimated to represent 20% of the total population
by 2040 [2]. The demographic change is even more pronounced in some European
countries, where the youngest segment of the population is not expected to grow.
For instance, in Switzerland the population segment of adults age 65 years and older
is expected to rise from 18.1% in 2015 to 26% in 2045 [3]. Relevant to health care
and health economics, the rapid increase in the proportion of older adults will
increase the burden of several age-related chronic diseases [4, 5].
Vitamin D may be a promising public health strategy to improve overall health
as suggested by prior mechanistic [6] and observational studies [7, 8], as well as by
P. O. Chocano-Bedoya (*)
Department of Geriatrics and Aging Research, University Hospital and University of Zurich,
Zurich, Switzerland
Centre on Aging and Mobility, University Hospital Zurich and Waid City Hospital,
Zurich, Switzerland
e-mail: [email protected]
H. A. Bischoff-Ferrari
Department of Geriatrics and Aging Research, University Hospital and University of Zurich,
Zurich, Switzerland
Centre on Aging and Mobility, University Hospital Zurich and Waid City Hospital,
Zurich, Switzerland
University Clinic for Acute Geriatric Care, City Hospital Waid, Zurich, Switzerland
e-mail: [email protected]
© Springer Nature Switzerland AG 2019 3
C. M. Weaver et al. (eds.), Nutritional Influences on Bone Health,
https://doi.org/10.1007/978-3-319-98464-3_1
