Table Of ContentNeuropsychiatry
Case Studies
Josef Priller
Hugh Rickards
Editors
123
Neuropsychiatry Case Studies
Josef Priller • Hugh Rickards
Editors
Neuropsychiatry Case
Studies
Editors
Josef Priller Hugh Rickards
Department of Neuropsychiatry Birmingham and Solihull MHFT
Charité – Universitätsmedizin Berlin Birmingham University
Berlin Edgbaston, Birmingham
Germany UK
ISBN 978-3-319-42188-9 ISBN 978-3-319-42190-2 (eBook)
DOI 10.1007/978-3-319-42190-2
Library of Congress Control Number: 2016960001
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Preface
In a narrow definition, neuropsychiatry deals with cognitive, emotional and behav-
ioural problems of neurological disorders. We have asked eminent neuropsychia-
trists from around the world to provide us with a case study that has taught them an
important lesson or has influenced their clinical care. The result is a collection of
cases that pay tribute to the diversity of neuropsychiatry.
The case observations are meant to inspire the reader. We hope that they stimu-
late curiosity and further exploration. The book contains excellent examples of neu-
ropsychiatric assessment and treatment approaches. However, we do not provide a
comprehensive overview of neuropsychiatry, nor does the book contain the latest
scientific discoveries.
Neuropsychiatry has a long tradition in Europe. The discipline has now been
established worldwide to provide the clinical skills that are required to link brain
structure and function. The authors of this book come from three continents and ten
different countries. They share an enthusiasm for neuropsychiatry, which we hope
you will enjoy.
Berlin, Germany Josef Priller
Edgbaston, Birmingham, UK Hugh Rickards
v
Contents
Part I Dementias
1 Unexplained Delirium, Atypical Dementia,
and Prodromal DLB . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Ian McKeith
2 Unable to Talk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Fernando Lázaro Perlado
3 A Mistaken Recurrent Depression . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Eike Jakob Spruth
4 An Atypical Variant of a Common Neurodegenerative Disorder. . . . . 17
Adith Mohan, Teresa Lee, and Perminder Sachdev
5 Posterior Cortical Atrophy (PCA) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Tillmann Supprian
6 Case Study: Little Red Riding Hood . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Marlies Baldee-Hordijk and Erik van Duijn
7 Not All Unusual Behavior Is Psychotic . . . . . . . . . . . . . . . . . . . . . . . . . . 37
Kevin Foy
8 Puzzling Case: Is the Answer in the Genes? . . . . . . . . . . . . . . . . . . . . . . 41
Emma Devenney and John Hodges
Part II Movement Disorders
9 Hallucinations in Parkinson’s Disease . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Roger A. Barker and Gemma Cummins
10 Parkinsons and Parasomnias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55
Hugh Selsick
vii
viii Contents
11 The Possible Talents of Tourette Syndrome . . . . . . . . . . . . . . . . . . . . . . 61
Andrea E. Cavanna
12 On the Nature of Separation Challenges and Attachment
Solutions in Severe, Refractory Gilles de la Tourette
Syndrome (GTS): Deep Brain Stimulation (DBS) Has Been
Helpful, But What About Rikki and Luci and Now Riley? . . . . . . . . . 67
James F. Leckman
13 Paroxysmal Disorders in Autism: Problems with Diagnosis
and Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Kanu Achinivu
14 Twitches and Fidgets Might Not Tell the Whole Story . . . . . . . . . . . . . 81
Mary May Robertson, Valsamma Eapen, and Renata Rizzo
15 Apathy in Huntington’s Disease: Medicating the Patient,
Spouse, Both, or None? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89
Harald Gelderblom
Part III Functional Disorders
16 Diagnostic Layers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95
Tiago Teodoro and Mark J. Edwards
17 A Case of a Familial “Dopamine-Responsive” Movement
Disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99
J.M. Gelauff and M.A.J. de Koning-Tijssen
18 Facial Spasm Can Look Like Facial Weakness in Patients
with Functional Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103
Jon Stone
19 Review of Notes Documenting Initial Treatment Is Crucial
in the Assessment of Acquired Brain Injury . . . . . . . . . . . . . . . . . . . . 109
Killian Welch
Part IV Epilepsy and Psychogenic Nonepileptic Seizures
20 Novel Seizure Semiology After Epilepsy Surgery . . . . . . . . . . . . . . . . 115
Martin Holtkamp
21 The Syndrome of Transient Epileptic Amnesia . . . . . . . . . . . . . . . . . . 121
Adam Zeman
22 Autobiographical Amnesia in Association with Subtle
Temporal Lobe Seizures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127
Christopher R. Butler
23 A Diagnostic Challenge of Troublesome Nocturnal Episodes . . . . . . . 131
Frank Besag
Contents ix
24 Past Investigations May Be Misleading . . . . . . . . . . . . . . . . . . . . . . . . . 137
Gregory S. Finucane
25 New Type of Paroxysmal Events in a Patient with Epilepsy
and Learning Difficulties . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
Maria (Meritxell) Oto
26 Is Less Really More? The Pitfalls of an Ambitiously
Healthy Diet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147
Marion Lautenschlager
Part V Metabolic Disorders and Autoimmune Encephalopathies
27 Neurometabolic Conditions May Coexist with Symptoms
of Autism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157
Susan Byrne and Tammy Hedderly
28 With the Help of a German Dermatologist . . . . . . . . . . . . . . . . . . . . . . 161
Josef Priller
29 A Musician Presents with Unusual Facial Movements,
Insomnia, and Depression . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167
Mark Groves
30 The Division Between Psychiatric and Neurological Practice
Does Not Help Patients with Disorders That Span the Two . . . . . . . . 171
Belinda Lennox
31 First-Episode Psychosis with Autoimmune Antibodies
Involving Clear Neuropsychological Impairment with
Common and Unusual Features . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175
Patrick Vesey, Paul Maddison, Eileen Ellen T. O’Regan,
and Eleanor Williams
32 Subacute Onset of Psychosis with Epileptic Seizures
and Dysautonomia: Think Autoimmunity! . . . . . . . . . . . . . . . . . . . . . 181
Til Menge, Diamandis Toutzaris, and Rüdiger J. Seitz
33 Case Study: Anti-GAD Encephalitis . . . . . . . . . . . . . . . . . . . . . . . . . . . 185
Helen Walker, Ashwani Jha, Paul Holmes, Thomasin Andrews,
Michael Kopelman, and Mervi Pitkanen
Part VI Organic Psychosis and Organic Personality Disorders
34 Animals in My Tummy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193
Fernando Lázaro Perlado
35 Personality Changes After Encephalitis: When “Organic
Personality Disorder” Is Not Enough . . . . . . . . . . . . . . . . . . . . . . . . . . 199
Maria del Mar Amador and Thomas Mauras
x Contents
36 Case Vignette. Brain Injury Can Make One Better! . . . . . . . . . . . . . . 207
Kanu Achinivu
Part VII Other Neuropsychiatric Disorders
37 Psychosis Following Traumatic Brain Injury . . . . . . . . . . . . . . . . . . . . 213
Tarek Zghoul and Kieran O’Driscoll
38 Bilateral Lesions of the Thalamus: A Neuropsychiatric
Challenge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217
Lars Wojtecki and Alfons Schnitzler
39 Listening to the Music and the Patient . . . . . . . . . . . . . . . . . . . . . . . . . 223
Jan Adriaan Coebergh
40 Autistic Disorder in Neurofibromatosis . . . . . . . . . . . . . . . . . . . . . . . . 227
Stefanie C. Linden
41 Case Vignette: When You Can’t Make Sense of the Story . . . . . . . . . 231
Hilary Lloyd
Contributors
Kanu Achinivu, MBBS, MSc, MRCPsych Department of Neuropsychiatry,
National Centre for Mental Health, The Barberry, Birmingham, UK
Thomasin Andrews, BSc, MD, FRCP Department of Neurology,
Guy’s and St Thomas’ NHS Foundation Trust, St Thomas’ Hospital,
London, UK
Marlies Baldee-Hordijk, MD Centre for Mental Health Care Delfland,
Delft, The Netherlands
Roger A. Barker, BA, MBBS, MRCP, PhD John van Geest Centre
for Brain Repair, Addenbrooke’s Hospital, Cambridge, UK
Frank Besag, BSc, MSc, PhD, MBChB East London NHS Foundation Trust,
Mid Bedfordshire Clinic, Bedford, UK
Christopher R. Butler, MA, MRCP, PhD Department of Clinical Neurosciences,
John Radcliffe Hospital, Oxford, UK
Susan Byrne, MB, BAO, BCh, PhD, MRCPI, MRCPCH Paediatric Neurology,
Evelina Children’s Hospital, St. Thomas’ Hospital, London, UK
Andrea E. Cavanna, MD, PhD Department of Neuropsychiatry,
The Barberry National Centre for Mental Health, Birmingham, UK
Jan Adriaan Coebergh, MBBS, FRCP Department of Neurology,
Ashford St Peter’s Foundation NHS Trust, Chertsey, UK
Gemma Cummins, MB, MRCPI John van Geest Centre for Brain Repair,
Addenbrooke’s Hospital, Cambridge, UK
M. A. J. de Koning-Tijssen, MD, PhD Department of Neurology,
University Medical Center Groningen, Groningen, The Netherlands
Maria del Mar Amador, MD Département de Neurologie,
Groupe Hospitalier Pitié-Salpétriêre, Paris, France
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