Neoplastic lesions of the skin

381 Pages·2014·45.944 MB·English

by  José A. Plaza, Victor G. Prieto

Demos Surgical
Series Editor: Saul Suster
Pathology Guides
Neoplastic
Lesions of
the Skin
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Demos Surgical Pathology Guides
Neoplastic Lesions of the Skin
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SERIES EDITOR
Saul Suster, MD
Professor and Chairman
Department of Pathology
Medical College of Wisconsin
Milwaukee, Wisconsin
TITLES
• Head and Neck Pathology
Paul E. Wakely
• Breast Pathology
Giovanni Falconieri, Janez Lamovec, and Abiy B. Ambaye
• Inflammatory Skin Disorders
Jose A. Plaza and Victor G. Prieto
• Lymph Nodes
Horatiu Olteanu, Alexandra M. Harrington, and Steven H. Kroft
• Neoplastic Lesions of the Skin
Jose A. Plaza and Victor G. Prieto
FORTHCOMING TITLES
• Pulmonary Pathology
R. Nagarjun Rao and Cesar A. Moran
• Soft Tissues
Eduardo V. Zambrano
• Prostate Pathology
Debra Zynger and Anil V. Parwani
• Liver Pathology
Shu-Yuan Xiao and Kiyoko Oshima
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Demos Surgical Pathology Guides
Neoplastic Lesions of the Skin
JOSE A. PLAZA, MD
Director of Dermatopathology
Medical College of Wisconsin
Milwaukee, Wisconsin
VICTOR G. PRIETO, MD, PhD
Director of Dermatopathology
University of Texas–MD Anderson Cancer Center
Houston, Texas
New York
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ISBN: 978-1-933864-86-0
e-book ISBN: 9781935281979
Acquisitions Editor: Rich Winters
Compositor: diacriTech
Visit our website at www.demosmedpub.com
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Library of Congress Cataloging-in-Publication Data
Plaza, Jose A.
Neoplastic lesions of the skin / Jose A. Plaza, MD Medical College of
Wisconsin, Milwaukee, Wisconsin, Victor G. Prieto, MD, PhD, MD Anderson
Cancer Center, Houston, Texas.
pages cm—(Demos surgical pathology guides)
Includes bibliographical references and index.
ISBN 978-1-933864-86-0
1. Skin—Cancer—Diagnosis. 2. Skin—Diseases—Diagnosis. I. Prieto,
Victor G. II. Title.
RC280.S5P57 2014
616.99’477—dc23
2013028151
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Printed in the United States of America by Bradford & Bigelow.
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Contents
Series Foreword xiii
Preface xv
1. Epithelial/Epidermal Lesions 1
Epidermal Nevi 2
Nevus Comedonicus 4
Seborrheic Keratosis 5
Warty Dyskeratoma 8
Epidermolytic Acanthoma 9
Acantholytic Acanthoma 10
Focal Acantholytic Dyskeratosis 11
Clear Cell Acanthoma 12
Actinic Keratosis 14
Squamous Cell Carcinoma 16
Invasive Squamous Cell Carcinoma 18
Verrucous Carcinoma 22
Lymphoepithelioma-Like Carcinoma 24
Keratoacanthoma 25
Bowenoid Papulosis 28
Merkel Cell Carcinoma (Neuroendocrine Carcinoma of
the Skin) 30
Mammary and Extramammary Paget Disease 34
2. Adnexal Neoplasms 39
Follicular Tumors 42
Trichoadenoma 42
Trichofolliculoma 43
Sebaceous Trichofolliculoma 44
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Trichoepithelioma 45
Desmoplastic Trichoepithelioma 48
Trichilemmoma 50
Desmoplastic Trichilemmoma 52
Trichilemmal Carcinoma 54
Trichoblastoma 56
Basal Cell Carcinoma 58
Nevoid Basal Cell Carcinoma Syndrome (Gorlin–Goltz) 61
Fibroepithelioma of Pinkus 62
Cutaneous Lymphadenoma 64
Tumor of the Follicular Infundibulum 66
Dilated Pore of Winer 67
Pilar Sheath Acanthoma 68
Perifollicular Fibroma 69
Fibrofolliculoma 70
Trichodiscoma 71
Pilomatricoma 72
Pilomatrical Carcinoma 74
Sebaceous Lesions 76
Ectopic Sebaceous Glands (Fordyce Spots and Montgomery Tubercles) 76
Sebaceous Hyperplasia 77
Folliculosebaceous Cystic Hamartoma 78
Nevus Sebaceus 79
Sebaceous Adenoma 80
Sebaceoma/Sebaceous Epithelioma 82
Sebaceous Carcinoma 84
Muir–Torre Syndrome 88
Sweat Gland (Eccrine and Apocrine) Neoplasms 92
Hidradenoma Papilliferum 92
Syringocystadenoma Papilliferum 94
Tubular Apocrine Adenoma 95
vi Contents
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Nipple Adenoma 96
Ceruminoma (Ceruminous Gland Tumor) 97
Myoepithelioma 98
Syringoma 99
Hidradenoma (Clear-Cell Hidradenoma) 101
Hidradenocarcinomas 104
Hidroacanthoma Simplex 106
Poroma 108
Dermal Duct Tumor 110
Porocarcinoma 112
Spiradenoma 114
Spiradenocarcinoma 116
Cylindroma 117
Malignant Cylindroma 118
Chondroid Syringoma (Mixed Tumor) 119
Malignant Chondroid Syringoma (Malignant Mixed Tumor) 120
Primary Mucinous Carcinoma 121
Eccrine Ductal Carcinoma 124
Microcystic Adnexal Carcinoma 126
Papillary Eccrine Adenoma 128
Aggressive Digital Papillary Adenocarcinoma 129
3. Cutaneous Cysts 131
Follicular Infundibular Cyst 132
Follicular Trichilemmal Cyst (Pilar Cyst) 134
Proliferating Trichilemmal Cyst 136
Pilonidal Cyst 138
Verrucous Cyst 140
Vellus Hair Cyst 142
Steatocystoma Multiplex 144
Dermoid Cyst 146
Hidrocystoma 147
Cutaneous Ciliated Cyst 148
Contents vii
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Thyroglossal Duct Cyst 150
Cervical Thymic Cyst 151
Branchial Cleft Cyst 152
Bronchogenic Cyst 153
Median Raphe Cyst 154
Pseudocyst of the Auricle 155
4. Connective Tissue Tumors 157
Adipocytic and Smooth Muscle Tumors 160
Lipoma 160
Angiolipoma 162
Spindle Cell Lipoma 163
Pleomorphic Lipoma 164
Nevus Lipomatosus Superficialis/Dermatolipoma 165
Pilar Leiomyoma 166
Angioleiomyoma 168
Smooth Muscle Hamartoma 169
Leiomyosarcoma 170
Fibrous and Myofibroblastic Tumors 172
Keloid 172
Nodular Fasciitis 174
Elastofibroma 176
Nuchal Fibroma 178
Gardner Fibroma 180
Fibroepithelial Polyp (Acrochordon) 181
Pleomorphic Fibroma 182
Sclerotic Fibroma (Storiform Collagenoma) 184
Superficial Acral Fibromyxoma 185
Superficial Angiomyxoma 187
Acquired Digital Fibrokeratoma 189
Fibrous Hamartoma of Infancy 191
Infantile Digital Fibromatosis 193
viii Contents
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Fibromatosis 195
Angiofibromas (Adenoma Sebaceum) 197
Fibrous Papule of the Nose 198
Pearly Penile Papules 199
Fibrohistiocytic Tumors 200
Multinucleated Cell Angiohistiocytoma 200
Dermatofibroma 202
Dermatofibrosarcoma Protuberans 206
Fibrohistiocytic Lesion With Atypical Features 210
Giant Cell Tumor of Tendon Sheath 212
Angiomatoid Fibrous Histiocytoma 214
Atypical Fibroxanthoma 216
Plexiform Fibrohistiocytic Tumor 218
Vascular Neoplasms 220
Infantile Hemangioma 220
Verrucous Hemangioma 221
Cherry Angioma 223
Pyogenic Granuloma/Lobular Capillary Hemangioma 224
Arteriovenous Hemangioma 225
Microvenular Hemangioma 226
Hobnail Hemangioma 227
Acquired Elastotic Hemangioma 229
Angiokeratoma 230
Spindle Cell Hemangioma (Hemangioendothelioma) 231
Cutaneous Epithelioid Angiomatous Nodule 232
Epithelioid Hemangioma (Angiolymphoid Hyperplasia With Eosinophilia) 232
Glomeruloid Hemangioma 234
Venous Lake 235
Intravascular Papillary Endothelial Hyperplasia (Masson Tumor) 236
Lymphangioma 238
Eccrine Angiomatous Hamartoma 240
Glomus Tumor 241
Contents ix
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