Table Of ContentMotivational Factors
in the Etiology
of Drug Abuse -
Volume 50 of the
Nebraska
Symposium on
Motivation
Richard A. Dienstbier Series Editor
Rick A. Bevins and
Michael T. Bardo Editors
University of Nebraska Press
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Volume50of
theNebraskaSymposium
onMotivation
UniversityofNebraskaPress
LincolnandLondon
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Volume 50 of the
Nebraska Motivational
Symposium on Factors
Motivation in the Etiology
of Drug Abuse
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RichardA.Dienstbier SeriesEditor
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Presenters Normal Page
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GeorgeF.Koob TheScrippsResearchInstitute
HarrietdeWit TheUniversityofChicago
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R.D.Spealman NewEnglandPrimateResearch
Center,HarvardMedicalSchool
JaakPanksepp BowlingGreenStateUniversity
MichaelT.Bardo UniversityofKentucky
RoyA.Wise NationalInstituteonDrugAbuse,
NIH
JaneStewart ConcordiaUniversity,Montreal,
Quebec,Canada
M.Vogel-Sprott UniversityofWaterloo
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MotivationalFactorsintheEtiologyofDrugAbuseisVolume50intheseries
CURRENTTHEORYANDRESEARCH
INMOTIVATION
©2004bytheUniversityofNebraskaPress
Allrightsreserved
ManufacturedintheUnitedStatesofAmerica
InternationalStandardBookNumber
0-8032-1340-9(Clothbound)
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Preface
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Thevolumeeditorsforthis50theditionoftheNebraskaSymposium ———
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are RickA. Bevins and Michael T. Bardo. Rick is anAssociate Pro-
fessorofPsychologyattheUniversityofNebraska.However,forthe PgEnds: TEX
firsttimethevolumeincludesaneditorfromoutsidetheUniversity
ofNebraskasystem.MikeisaProfessorofPsychologyattheUniver-
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sityofKentucky.RickandMikecoordinatedthesymposiumthatled
to this volume with enthusiasm and dedication, and they worked
with the SymposiumAdvisory Committee in developing plans for
celebrating this half-century of our Symposium. Coordinating the
volume means that Rick and Mike did most of the “heavy lifting,”
fromplanningthevolume,toselectingandinvitingthecontributors,
and to coordinating all aspects of the editing. My thanks to them
and the contributors for the very timely production of their chap-
ters.
As with Symposium sessions of the last several years, to allow
other scholars to travel to the Symposium as participants, we in-
vited posters relevant to the main theme of addiction. This poster
session included 35 submissions from researchers in places such as
BostonUniversity,unc–ChapelHill,DenisonUniversity,University
ofGiessen,UniversityofSouthDakota,andUniversityofMinnesota.
Sincethisisatraditionwewillcontinue,weurgeyou,ourreaders,
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MotivationalFactorsintheEtiologyofDrugAbuse/RickA.Bevins
vi
motivational factors in the etiology of drug abuse
to consider such poster submissions when you receive future Sym-
posiumannouncements.
This Symposium series is supported largely by funds donated
inthememoryofProfessorHarryK.WolfetotheUniversityofNe-
braskaFoundationbythelateProfessorCoraL.Friedline.ThisSym-
posium volume, like those of the recent past, is dedicated to the
memory of Professor Wolfe, who brought psychology to the Uni-
versityofNebraska.AfterstudyingwithProfessorWilhelmWundt,
ProfessorWolfereturnedtothis,hisnativestate,toestablishthefirst
undergraduatelaboratoryofpsychologyinthenation.Asastudent
atNebraska,ProfessorFriedlinestudiedpsychologyunderProfessor
Wolfe.
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We are grateful to the late Professor Friedline for this bequest,
andtotheUniversityofNebraskaFoundationforcontinuedfinancial
supportfortheseries.Forthis50thanniversaryyear,andforsubse-
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quentyears,theamountoffundinggrantedbytheFoundationhas
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beenincreased.WeareparticularlygratefultoSeniorViceChancellor
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forAcademicAffairsRichardEdwardsforassistanceinsecuringthat
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increase.
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It is time to give a special thanks to Claudia Price-Decker, who
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regularly helps with the coordination of the sessions themselves,
overseeing the many details that must be considered for the Sym-
posiumtorunsmoothly.Claudiaisgreat,sheisappreciated,andwe [-6], (2)
havecometotakesmoothrunningforgranted.Otherswhohelpand
deservethanksincludeBeckiBarnes,whohasbeenhelpingforyears,
andJoyMenkewhohasjoinedthiseffortmorerecently.
RichardA.Dienstbier
SeriesEditor
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Contents
ix RickA.Bevinsand Introduction:Motivation,Drug
MichaelT.Bardo Abuse,and50YearsofTheoretical
andEmpiricalInquiry
1 GeorgeF.Koob Allostatic View of Motivation:
ImplicationsforPsychopathology
19 HarrietdeWitand DualDeterminantsofDrugUsein
JerryB.Richards Humans:RewardandImpulsivity
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57 R.D.Spealman,B.Lee, TriggersofRelapse:Nonhuman
S.Tiefenbacher,D.M.Platt, Primate Models of Reinstated
J.K.Rowlett,and CocaineSeeking Lines: 23 to 56
T.V.Khroyan
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85 JaakPanksepp,Christine The Role of Emotional Systems * 24.3896pt PgVar
Nocjar,JeffBurgdorf,Jules inAddiction:ANeuroethological ———
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B.Panksepp,andRobert Perspective
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127 Michael T. Bardo and Biological Connection between
LindaP.Dwoskin Novelty- and Drug-seeking [-7], (3)
MotivationalSystems
159 RoyA.Wise Drive, Incentive, and
Reinforcement:TheAntecedents
andConsequencesofMotivation
197 JaneStewart Pathways to Relapse: Factors
Controlling the Reinitiation of
DrugSeekingafterAbstinence
235 M.Vogel-Sprott Drugs, Behavior, and
Environmental Sources of
Motivation:BridgingaGap
261 SubjectIndex
271 AuthorIndex
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Introduction:
Motivation, DrugAbuse,
and 50 Years of
Theoretical and
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Inreviewingthe25-yearhistoryoftheNebraskaSymposiumonMo-
tivation,BenjaminandJones(1979)notedthattheSymposiumwas
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“thelongest-livedtopicalseriesinAmericanpsychology,withana-
tional and international reputation” (p. ix). On March 28 and 29 of
2002,withapackedauditoriumonthecampusoftheUniversityof
Nebraska–Lincoln,thisrecordwasdoubledinlife.Asthereaderwill
quicklyseefromthelistofcontributors,thereputationoftheSympo-
siumwasalsomaintainedonits50thAnniversary.Beforecontinuing,
wewouldliketoreiteratethethanksinthePrefaceforallthosewho
supported the Symposium with their hard work, thoughtful effort,
andgeneroussupport.Wearealsogratefultotheselectioncommit-
teeforchoosingourproposalforthe50thNebraskaSymposiumon
Motivation.Webelieveitisfittingthatdrugabusebethetopicforthis
Symposium.Drugabuseanditsassociatedpersonalandfiscalcosts
reflectthelargesthealthproblemintheUnitedStates(RobertWood
JohnsonFoundation,2001).Psychology,asabroadintegratedfieldof
inquiry,hasmuchtocontributetounderstandingandsolvingthisse-
riousproblem.Thecontentsofthisvolumeclearlysupportthisclaim.
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Description:This volume marks the fiftieth anniversary of the Nebraska Symposium on Motivation, the longest continuously running symposium in the field of psychology. The motivational processes involved in drug abuse, the largest health problem in the United States, are the subject of eight thought-provoking es