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About Molecular Minimal Residual Disease Detection in Acute Myeloid Leukemia
The document summarizes a presentation given at the 32nd General Annual Meeting of the Belgian Hematology Society on molecular minimal residual disease (MRD) detection in acute myeloid leukemia (AML). It discusses how MRD monitoring based on single molecular targets like mutant NPM1 provides prognostic information. It also explores whether next generation sequencing (NGS) could further improve risk stratification in AML by enabling MRD detection using multiple molecular markers. Data is presented showing mutant NPM1 MRD status combined with FLT3-ITD defines relapse risk and that NGS allows monitoring of over 50 recurrently mutated genes in AML.
Detailed Information
| Author: | ['A'] |
|---|---|
| Publication Year: | 2020 |
| Pages: | 42 |
| Language: | English |
| Format: | |
| Price: | FREE |
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