Table Of ContentJournal of Biomedicine and Biotechnology
Molecular Image-Guided Theranostic
and Personalized Medicine 2012
Guest Editors: Hong Zhang, Mei Tian, Enzhong Li,
Yasuhisa Fujibayashi, Lie-Hang Shen, and David J. Yang
Molecular Image-Guided Theranostic and
PersonalizedMedicine 2012
Journal of Biomedicine and Biotechnology
Molecular Image-Guided Theranostic and
PersonalizedMedicine 2012
Guest Editors: Hong Zhang, Mei Tian, Enzhong Li,
Yasuhisa Fujibayashi, Lie-Hang Shen, and David J. Yang
Copyright © 2012 Hindawi Publishing Corporation. All rights reserved.
This is a special issue published in “Journal of Biomedicine and Biotechnology.” All articles are open access articles distributed under
the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original work is properly cited.
Editorial Board
The editorial board of the journal is organized into sections that correspond to
the subject areas covered by the journal.
Agricultural Biotechnology
Ahmad Z. Abdullah, Malaysia Ian Godwin, Australia Rodomiro Ortiz, Sweden
Guihua H. Bai, USA Hari B. Krishnan, USA B. C. Saha, USA
Christopher P. Chanway, Canada Carol A. Mallory-Smith, USA Mariam B. Sticklen, USA
Ravindra N. Chibbar, Canada Dennis P. Murr, Canada Chiu-Chung Young, Taiwan
Animal Biotechnology
E. S. Chang, USA Tosso Leeb, Switzerland Lawrence B. Schook, USA
Bhanu P. Chowdhary, USA James D. Murray, USA Mari A. Smits, The Netherlands
Noelle E. Cockett, USA Anita M. Oberbauer, USA Leon Spicer, USA
Peter Dovc, Slovenia Jorge A. Piedrahita, USA J. Verstegen, USA
Scott C. Fahrenkrug, USA Daniel Pomp, USA Matthew B. Wheeler, USA
Dorian J. Garrick, USA Kent M. Reed, USA Kenneth L. White, USA
Thomas A. Hoagland, USA Lawrence Reynolds, USA
Biochemistry
Robert Blumenthal, USA Paul W. Doetsch, USA Wen-Hwa Lee, USA
David Ronald Brown, UK Hicham Fenniri, Canada Richard D. Ludescher, USA
Saulius Butenas, USA Nick V. Grishin, USA George Makhatadze, USA
Vittorio Calabrese, Italy J. Guy Guillemette, Canada Leonid Medved, USA
Miguel Castanho, Portugal Paul W. Huber, USA Susan A. Rotenberg, USA
Francis J. Castellino, USA Chen-Hsiung Hung, Taiwan Jason Shearer, USA
Roberta Chiaraluce, Italy Michael Kalafatis, USA Andrei Surguchov, USA
D. M. Clarke, Canada B. E. Kemp, Australia John B. Vincent, USA
Francesca Cutruzzola`, Italy Phillip E. Klebba, USA Y. George Zheng, USA
Bioinformatics
T. Akutsu, Japan Stavros J. Hamodrakas, Greece Florencio Pazos, Spain
Miguel A. Andrade, Germany Paul Harrison, USA Zhirong Sun, China
Mark Y. Borodovsky, USA George Karypis, USA Ying Xu, USA
Rita Casadio, Italy Jack A. Leunissen, The Netherlands Alexander Zelikovsky, USA
Artem Cherkasov, Canada Guohui Lin, Canada Albert Zomaya, Australia
David Corne, UK Satoru Miyano, Japan
Sorin Draghici, USA Zoran Obradovic, USA
Biophysics
Miguel Castanho, Portugal Ali A. Khraibi, Saudi Arabia S. B. Petersen, Denmark
P. Bryant Chase, USA Rumiana Koynova, USA Peter Schuck, USA
Kuo-Chen Chou, USA Serdar Kuyucak, Australia Claudio M. Soares, Portugal
Rizwan Khan, India Jianjie Ma, USA
Cell Biology
Omar Benzakour, France Xudong Huang, USA Michael Sheetz, USA
Sanford I. Bernstein, USA Anton M. Jetten, USA James L. Sherley, USA
Phillip I. Bird, Australia Seamus J. Martin, Ireland G. S. Stein, USA
Eric Bouhassira, USA Manuela Martins-Green, USA Richard Tucker, USA
Mohamed Boutjdir, USA Shoichiro Ono, USA Thomas van Groen, USA
Chung-Liang Chien, Taiwan George Perry, USA Andre Van Wijnen, USA
Richard Gomer, USA M. Piacentini, Italy Steve Winder, UK
Paul J. Higgins, USA George E. Plopper, USA Chuanyue Wu, USA
Pavel Hozak, Czech Republic Lawrence Rothblum, USA Bin-Xian Zhang, USA
Genetics
Adewale Adeyinka, USA J. Spencer Johnston, USA Raj S. Ramesar, South Africa
Claude Bagnis, France M. Ilyas Kamboh, USA Elliot D. Rosen, USA
J. Birchler, USA Feige Kaplan, Canada Dharambir K. Sanghera, USA
Susan Blanton, USA Manfred Kayser, The Netherlands Michael Schmid, Germany
Barry J. Byrne, USA Brynn Levy, USA Markus Schuelke, Germany
R. Chakraborty, USA Xiao Jiang Li, USA Wolfgang Arthur Schulz, Germany
Domenico Coviello, Italy Thomas Liehr, Germany Jorge Sequeiros, Portugal
Sarah H. Elsea, USA James M. Mason, USA Mouldy Sioud, Norway
Celina Janion, Poland Mohammed Rachidi, France Rongjia Zhou, China
Genomics
Vladimir Bajic, Saudi Arabia Vladimir Larionov, USA Yasushi Okazaki, Japan
Margit Burmeister, USA Thomas Lufkin, Singapore Gopi K. Podila, USA
Settara Chandrasekharappa, USA Joakim Lundeberg, Sweden Momiao Xiong, USA
Yataro Daigo, Japan John L. McGregor, France
J. Spencer Johnston, USA John V. Moran, USA
Immunology
Hassan Alizadeh, USA James D. Gorham, USA Kanury V. S. Rao, India
Peter Bretscher, Canada Silvia Gregori, Italy Yair Reisner, Israel
Robert E. Cone, USA Thomas Griffith, USA Harry W. Schroeder, USA
Terry L. Delovitch, Canada Young S. Hahn, USA Wilhelm Schwaeble, UK
Anthony L. DeVico, USA Dorothy E. Lewis, USA Nilabh Shastri, USA
Nick Di Girolamo, Australia Bradley W. McIntyre, USA Yufang Shi, China
Don Mark Estes, USA R. Lee Mosley, USA Piet Stinissen, Belgium
Soldano Ferrone, USA Marija Mostarica-Stojkovic´, Serbia Hannes Stockinger, Austria
Jeffrey A. Frelinger, USA Hans Konrad Muller, Australia J. W. Tervaert, The Netherlands
John Robert Gordon, Canada Ali Ouaissi, France Graham R. Wallace, UK
Microbial Biotechnology
Jozef Anne´, Belgium Luca Simone Cocolin, Italy Yanhe Ma, China
Yoav Bashan, Mexico Peter Coloe, Australia Bernd H. A. Rehm, New Zealand
Marco Bazzicalupo, Italy Daniele Daffonchio, Italy Angela Sessitsch, Austria
Nico Boon, Belgium Han de Winde, The Netherlands
Microbiology
D. Beighton, UK Gad Frankel, UK Didier A. Raoult, France
Steven R. Blanke, USA Roy Gross, Germany Isabel Sa´-Correia, Portugal
Stanley Brul, The Netherlands Hans-Peter Klenk, Germany P. L. C. Small, USA
Isaac K. O. Cann, USA Tanya Parish, UK Michael Thomm, Germany
Stephen K. Farrand, USA Gopi K. Podila, USA H. C. van der Mei, The Netherlands
Alain Filloux, UK Frederick D. Quinn, USA Schwan William, USA
Molecular Biology
Rudi Beyaert, Belgium Wuyuan Lu, USA William S. Trimble, Canada
Michael Bustin, USA Patrick Matthias, Switzerland Lisa Wiesmuller, Germany
Douglas Cyr, USA John L. McGregor, France Masamitsu Yamaguchi, Japan
K. Iatrou, Greece S. L. Mowbray, Sweden
Lokesh Joshi, Ireland Elena Orlova, UK
David W. Litchfield, Canada Yeon-Kyun Shin, USA
Oncology
Colin Cooper, UK Steve B. Jiang, USA Allal Ouhtit, Oman
F. M. J. Debruyne, The Netherlands Daehee Kang, Republic of Korea Frank Pajonk, USA
Nathan Ames Ellis, USA Abdul R. Khokhar, USA Waldemar Priebe, USA
Dominic Fan, USA Rakesh Kumar, USA F. C. Schmitt, Portugal
Gary E. Gallick, USA Macus Tien Kuo, USA Sonshin Takao, Japan
Daila S. Gridley, USA Eric W. Lam, UK Ana Maria Tari, USA
Xin-yuan Guan, Hong Kong Sue-Hwa Lin, USA Henk G. Van Der Poel, The Netherlands
Anne Hamburger, USA Kapil Mehta, USA Haodong Xu, USA
Manoor Prakash Hande, Singapore Orhan Nalcioglu, USA David J. Yang, USA
Beric Henderson, Australia P. J. Oefner, Germany
Pharmacology
Abdel A. Abdel-Rahman, USA Dobromir Dobrev, Germany Daniel T. Monaghan, USA
M. Badr, USA Ayman El-Kadi, Canada T. Narahashi, USA
Stelvio M. Bandiera, Canada Jeffrey Hughes, USA Kennerly S. Patrick, USA
Ronald E. Baynes, USA Kazim Husain, USA Vickram Ramkumar, USA
R. Keith Campbell, USA Farhad Kamali, UK Michael J. Spinella, USA
Hak-Kim Chan, Australia Michael Kassiou, Australia Quadiri Timour, France
Michael D. Coleman, UK Joseph J. McArdle, USA Todd W. Vanderah, USA
J. Descotes, France Mark J. McKeage, New Zealand Val J. Watts, USA
Plant Biotechnology
Prem L. Bhalla, Australia Liwen Jiang, Hong Kong Ralf Reski, Germany
J. R. Botella, Australia Pulugurtha Bharadwaja Kirti, India Sudhir Kumar Sopory, India
Elvira Gonzalez De Mejia, USA Yong Pyo Lim, Republic of Korea
H. M. Ha¨ggman, Finland Gopi K. Podila, USA
Toxicology
Michael Aschner, USA Youmin James Kang, USA Kenneth Turteltaub, USA
Michael L. Cunningham, USA M. Firoze Khan, USA Brad Upham, USA
Laurence D. Fechter, USA Pascal Kintz, France
Hartmut Jaeschke, USA R. S. Tjeerdema, USA
Virology
Nafees Ahmad, USA Fred Kibenge, Canada Ralf Wagner, Germany
Edouard Cantin, USA Fenyong Liu, USA Jianguo Wu, China
Ellen Collisson, USA E´ ric Rassart, Canada Decheng Yang, Canada
Kevin M. Coombs, Canada Gerald G. Schumann, Germany Jiing-Kuan Yee, USA
Norbert K. Herzog, USA Y.-C. Sung, Republic of Korea Xueping Zhou, China
Tom Hobman, Canada Gregory Tannock, Australia Wen-Quan Zou, USA
Shahid Jameel, India
Contents
Molecular Image-Guided Theranostic and PersonalizedMedicine 2012, Hong Zhang, Mei Tian,
Enzhong Li, Yasuhisa Fujibayashi, Lie-Hang Shen, and David J. Yang
Volume 2012, Article ID 747416, 2 pages
Detection of Canonical Hedgehog Signaling in Breast Cancer by 131-Iodine-Labeled Derivatives of the
Sonic Hedgehog Protein, Jennifer Sims-Mourtada, David Yang, Izabela Tworowska, Richard Larson,
Daniel Smith, Ning Tsao, Lynn Opdenaker, Firas Mourtada, and Wendy Woodward
Volume 2012, Article ID 639562, 8 pages
Effectiveness of Myocardial Contrast Echocardiography Quantitative Analysis during Adenosine Stress
versus Visual Analysis before Percutaneous Therapy in Acute Coronary Pain: A Coronary Artery TIMI
Grading Comparing Study, Lixia Yang, Yuming Mu, Luiz Augusto Quaglia, Qi Tang, Lina Guan,
Chunmei Wang, and Ming Chi Shih
Volume 2012, Article ID 806731, 7 pages
In Vivo Visualization of Heterogeneous Intratumoral Distribution of Hypoxia-Inducible Factor-1α
Activity by the Fusion of High-Resolution SPECT andMorphological Imaging Tests, Hirofumi Fujii,
Masayuki Yamaguchi, Kazumasa Inoue, Yasuko Mutou, Masashi Ueda, Hideo Saji, Shinae Kizaka-Kondoh,
Noriyuki Moriyama, and Izumi O. Umeda
Volume 2012, Article ID 262741, 6 pages
99m
Development of Tc-N4-NIM forMolecular Imaging of Tumor Hypoxia, Mohammad S. Ali,
Fan-Lin Kong, Alex Rollo, Richard Mendez, Saady Kohanim, Daniel Lee Smith, and David J. Yang
Volume 2012, Article ID 828139, 9 pages
Molecular Imaging of Mesothelioma with 99mTc-ECG and 68Ga-ECG, Yin-Han Zhang, Jerry Bryant,
Fan-Lin Kong, Dong-Fang Yu, Richard Mendez, E. Edmund Kim, and David J. Yang
Volume 2012, Article ID 232863, 9 pages
Effect of Low Tube Voltage on Image Quality, Radiation Dose, and Low-Contrast Detectability at
Abdominal Multidetector CT: Phantom Study, Kun Tang, Ling Wang, Rui Li, Jie Lin, Xiangwu Zheng,
and Guoquan Cao
Volume 2012, Article ID 130169, 6 pages
Usefulness of FDG, MET and FLT-PET Studies for the Management of Human Gliomas, Keisuke Miyake,
Aya Shinomiya, Masaki Okada, Tetsuhiro Hatakeyama, Nobuyuki Kawai, and Takashi Tamiya
Volume 2012, Article ID 205818, 11 pages
111In-Labeled Cystine-Knot Peptides Based on the Agouti-Related Protein for Targeting Tumor
Angiogenesis, Lei Jiang, Zheng Miao, Richard H. Kimura, Adam P. Silverman, Gang Ren, Hongguang Liu,
Hankui Lu, Jennifer R. Cochran, and Zhen Cheng
Volume 2012, Article ID 368075, 8 pages
Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders,
Lie-Hang Shen, Mei-Hsiu Liao, and Yu-Chin Tseng
Volume 2012, Article ID 259349, 14 pages