Molecular, Cellular, and Tissue Engineering

1830 Pages·2016·20.07 MB·English

by  Bronzino J.D.

THE BIOMEDICAL ENGINEERING HANDBOOK
F O U R T H EDI T ION
Molecular,
Cellular, and
Tissue Engineering
Edited by
Joseph D. Bronzino
Donald R. Peterson
About the pagination of this eBook
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THE BIOMEDICAL ENGINEERING HANDBOOK
FOURTH EDITION
Molecular,
Cellular, and
Tissue Engineering

THE BIOMEDICAL ENGINEERING HANDBOOK
FOURTH EDITION
Molecular,
Cellular, and
Tissue Engineering
Edited by
Joseph D. Bronzino
Founder and President
Biomedical Engineering Alliance and Consortium (BEACON)
Hartford, Connecticut, U.S.A.
Donald R. Peterson
Professor of Engineering
Dean of the College of Science, Technology, Engineering, Mathematics, and Nursing
Texas A&M University – Texarkana
Texarkana, Texas, U.S.A.
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does not constitute endorsement or sponsorship by The MathWorks of a particular pedagogical approach or particular
use of the MATLAB® software.
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Contents
Preface.................................................................................................................... xiii
Editors .....................................................................................................................xix
Contributors ...........................................................................................................xxi
SECTION I Molecular Biology
Michael M. Domach
1
Historical Perspective and Basics of Molecular Biology ...............................1-1
Nathan R. Domagalski and Michael M. Domach
2
Biomolecular Interactions ..............................................................................2-1
Gordon Rule
3
Recent Advances in DNA Separations: Plasmid Purification, Rapid
Electrophoresis, and Affinity-Based Recovery..............................................3-1
James W. Schneider and Jeffrey M. Savard
4
Systems and Technology Involving Bacteria .................................................4-1
Nicole Bleckwenn and William Bentley
5
Expression in Mammalian Cells ....................................................................5-1
Tina Sauerwald and Michael Betenbaugh
6
DNA Vaccines Production and Engineering .................................................6-1
Michael M. Domach, Jonathan W. Meade, and Mohammad A. Ataai
SECTION II Transport Phenomena and Biomimetic Systems
Robert J. Fisher and Robert A. Peattie
7
Biomimetic Systems: Concepts, Design, and Emulation ..............................7-1
Robert J. Fisher
8
Transport/Reaction Processes in Biology and Medicine ..............................8-1
E.N. Lightfoot
9
Microvascular Heat Transfer .........................................................................9-1
James W. Baish
v
vi Contents
10
Fluid Dynamics for Bio Systems: Fundamentals and Model Analysis .......10-1
Robert A. Peattie and Robert J. Fisher
11
Animal Surrogate Systems ...........................................................................11-1
Michael L. Shuler, Sarina G. Harris, Xinran Li, and Mandy B. Esch
12
Arterial Wall Mass Transport: The Possible Role of Blood Phase
Resistance in the Localization of Arterial Disease .....................................12-1
John M. Tarbell and Yuchen Qiu
13
Transport Phenomena and the Microenvironment ....................................13-1
Robert J. Fisher and Robert A. Peattie
14
Transport and Drug Delivery through the Blood–Brain Barrier
and Cerebrospinal Fluid ..............................................................................14-1
Bingmei M. Fu
15
Interstitial Transport in the Brain: Principles for Local Drug Delivery ....15-1
W. Mark Saltzman
16
Surfactant Transport and Fluid–Structure Interactions during
Pulmonary Airway Reopening ....................................................................16-1
David Martin, Anne-Marie Jacob, and Donald P. Gaver III
SECTION III Physiological Modeling, Simulation, and Control
Joseph L. Palladino
17
Modeling Strategies and Cardiovascular Dynamics ...................................17-1
Joseph L. Palladino, Gary M. Drzewiecki, and Abraham Noordergraaf
18
Compartmental Models of Physiological Systems ......................................18-1
Claudio Cobelli, Giovanni Sparacino, Maria Pia Saccomani, Gianna Maria Toffolo,
and Andrea Caumo
19
Cardiovascular Models and Control ...........................................................19-1
Madhusudan Natarajan, Fernando Casas, and W.D. Timmons
20
Respiratory Models and Control .................................................................20-1
Chi-Sang Poon
21
Biomimetic Approaches to Physiological Control ......................................21-1
James J. Abbas and Amit Abraham
22
Methods and Tools for Identification of Physiologic Systems ....................22-1
Vasilis Z. Marmarelis
23
Modeling Vascular Vibrations: Autoregulation and Vascular Sounds ......23-1
Gary M. Drzewiecki, John K-J. Li, and Abraham Noordergraaf
24
External Control of Movements ..................................................................24-1
Dejan B. Popovic´ and Mirjana B. Popovic´
Contents vii
25
The Fast Eye Movement Control System .....................................................25-1
John Denis Enderle
26
A Comparative Approach to Analysis and Modeling of
Cardiovascular Function .............................................................................26-1
John K-J. Li, Ying Zhu, and Abraham Noordergraaf
27
A Biomedical and Biophysical Approach to the Science in
Cardiopulmonary Resuscitation ..................................................................27-1
Gerrit J. Noordergraaf, Igor W.F. Paulussen, Alyssa Venema, Gert Jan Scheffer, and
Abraham Noordergraaf
28
Kinematic Modeling of Left Ventricular Diastolic Function .....................28-1
Leonid Shmuylovich, Charles S. Chung, and Sándor J. Kovács
SECTION IV Stem Cell Engineering: An Introduction
David V. Schaffer
29
Engineering the Pluripotent Stem Cell Niche for Directed Mesoderm
Differentiation ..............................................................................................29-1
Céline L. Bauwens, Kelly A. Purpura, and Peter W. Zandstra
30
Cell Mechanobiology in Regenerative Medicine: Lessons from Cancer ....30-1
Badriprasad Ananthanarayanan and Sanjay Kumar
31
Systems-Engineering Principles in Signal Transduction and Cell-Fate
Choice ...........................................................................................................31-1
Karin J. Jensen, Anjun K. Bose, and Kevin A. Janes
32
Biomaterial Scaffolds for Human Embryonic Stem Cell Culture and
Differentiation ..............................................................................................32-1
Stephanie Willerth and David V. Schaffer
33
Stem Cells and Regenerative Medicine in the Nervous System ..................33-1
Shelly Sakiyama-Elbert
34
Stem Cells and Regenerative Medicine for Treating Damaged
Myocardium .................................................................................................34-1
Rohini Gupta, Kunal Mehtani, Kimberly R. Kam, and Kevin E. Healy
35
Stem Cells and Hematopoiesis .....................................................................35-1
Krista M. Fridley and Krishnendu Roy
36
Synthetic Biomaterials and Stem Cells for Connective Tissue
Engineering ..................................................................................................36-1
Ameya Phadke and Shyni Varghese
37
Derivation and Expansion of Human Pluripotent Stem Cells ....................37-1
Sean P. Palecek
38
Bioreactors for Stem Cell Expansion and Differentiation ..........................38-1
Carlos A.V. Rodrigues, Tiago G. Fernandes, Maria Margarida Diogo, Cláudia Lobato
da Silva, and Joaquim M.S. Cabral