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Mitochondrial Genetics and Cancer PDF

363 Pages·2010·2.231 MB·English
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by Gabriel D. Dakubo (auth.)| 2010| 363 pages| 2.231| English

About Mitochondrial Genetics and Cancer

The pivotal role of mitochondrial functions in carcinogenesis is quite well established. However, the critical role of mitochondrial genome alterations to cancer development is muted in traditional textbooks. Recent scientific efforts have provided unequivocal evidence for mitochondrial genome mutations and content changes in cancer development, progression, and therapy. This pioneering book is a unique compilation of mitochondrial genome alterations in cancer. While primarily focused on the emerging role of mitochondrial genome changes, bioenergetics and signaling pathways, attention is also given to the metabolic transformations of the cancer cell, as well as the established altered cell death processes that underlie cancer evolution and treatment resistance.

Detailed Information

Author:Gabriel D. Dakubo (auth.)
Publication Year:2010
ISBN:9783642114151
Pages:363
Language:English
File Size:2.231
Format:PDF
Price:FREE
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