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About MIT Anfinsen Lec 2
The document discusses the protein folding problem and key early experiments by Christian Anfinsen exploring how the amino acid sequence of a protein determines its 3D structure. It describes how protein denaturation led to questions about folding. It then details Anfinsen's experiments on refolding ribonuclease A in vitro which provided evidence that the amino acid sequence alone carries the information to determine the native structure.
Detailed Information
Author: | ['Satyaki Majumdar'] |
---|---|
Publication Year: | 2019 |
Pages: | 9 |
Language: | English |
Format: | |
Price: | FREE |
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